Breathing Together wheeze project

This repository contains the R code and documentation for the manuscript entitled "Children who have wheezed in early life exhibit bacterial, not fungal or viral, dysbiosis and a systemic monocyte immune signature". The analysis integrates multi-omics data to explore host-microbial interactions in the context of wheeze in early-life.

Contents

• project-breathingtogether-wheeze.Rmd: Main R Markdown document containing all data analyses leading to Figures 2-5 of the manuscript. This includes data preprocessing, detailed statistical analyses, and visualization.

• Functions.R: This script includes custom R functions utilized in the main R Markdown file. These functions facilitate data manipulation, perform statistical tests, and generate plots specific to the data.

Version

October 8, 2024

Data availability

All raw sequencing data are available at NCBI BioProject PRJNA1076275 alongside minimal metadata.