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Merge pull request #751 from vaccineontology/issue#740
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add 'IL-12-MOP (CTX-1796)' vaccine adjuvant
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zhengj2007 authored Sep 18, 2024
2 parents c10ab61 + f75d1fe commit 9adea3d
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36 changes: 36 additions & 0 deletions src/modules/vaccine_adjuvant.owl
Original file line number Diff line number Diff line change
Expand Up @@ -4915,6 +4915,42 @@ none</obo:IAO_0000116>



<!-- http://purl.obolibrary.org/obo/VO_0005509 -->

<owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005509">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0006109"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>Nucleic acid vaccine adjuvant that targets on cytokine receptor to induce a Th1-based response.</obo:IAO_0000115>
<obo:IAO_0000116>Chemical Nature: nucleic acid
Mechanism of Action: Cytokine Receptor
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Romain Micol, Combined Therapeutics

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=39047117

Ongoing clinical trials:
none</obo:IAO_0000116>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
<obo:IAO_0000117>Romain Micol</obo:IAO_0000117>
<obo:IAO_0000118>IL-12-MOP (CTX-1796)</obo:IAO_0000118>
<obo:IAO_0000119>Pubmed:39047117</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/740</obo:IAO_0000233>
<obo:VO_0005328>100</obo:VO_0005328>
<oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
<rdfs:label>IL-12-MOP (CTX-1796) vaccine adjuvant</rdfs:label>
</owl:Class>



<!-- http://purl.obolibrary.org/obo/VO_0006092 -->

<owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006092">
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14 changes: 13 additions & 1 deletion src/templates/vaccine_adjuvant.csv
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Expand Up @@ -1078,4 +1078,16 @@ Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=33735218

Ongoing clinical trials:
none",98,https://github.com/vaccineontology/VO/issues/731,,,Th1/Th2 mixed immune profile,,
none",98,https://github.com/vaccineontology/VO/issues/731,,,Th1/Th2 mixed immune profile,,
VO:0005509,IL-12-MOP (CTX-1796) vaccine adjuvant,vaccine adjuvant,nucleic acid vaccine adjuvant,IL-12-MOP (CTX-1796),Nucleic acid vaccine adjuvant that targets on cytokine receptor to induce a Th1-based response.,Pubmed:39047117,Nilufer kosar|Jie Zheng|Romain Micol,,"Chemical Nature: nucleic acid
Mechanism of Action: Cytokine Receptor
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Romain Micol, Combined Therapeutics

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=39047117

Ongoing clinical trials:
none",100,https://github.com/vaccineontology/VO/issues/740,,,Th1-biased immune profile,,
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