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coming soon docs
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ncherric committed Aug 29, 2023
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Expand Up @@ -115,3 +115,13 @@ You can delete the contents of ``./Iliad/workflow/cram_Snakefile`` and copy/past
Model organism genome processing
================================

Iliad has been developed, tested, applied with human genomic data.
However, the bioinformatic tools employed in these workflows can be translated to model organisms. Including other organisms (i.e., mice, flies, and bacteria) to the
functionality of this workflow toolkit is underway, but the code can be manually adapted to your liking in the meantime. Here is the suggested adaptations:

1. Follow the instructions above for variant discovery.
2. Change the ``CHROMS`` variable in ``./Iliad/workflow/common.smk`` on lines 26-27 to your appropriate organism.
3. Edit the ``./Iliad/config/config.yaml`` file variable ``AutoRetrieveReference: true`` to ``AutoRetrieveReference:`` AND ``IhaveReference:`` to ``IhaveReference: True``. Lines 65 and 70.
4. Add the file path to your reference genome on line 76. ``filePath: ./Iliad/resources/NEW-REFERENCE-GENOME-HERE.fa``

If you have already edited the ``config.yaml`` file previously with ``auto_config.py``, these line numbers provided above will be found in ``./Iliad/config/config-commented.yaml``.

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