CHEX-seq Data Analysis Scripts

Overview

This repository contains code for CHEX-seq data analysis to promote transparent science. For CHEX-seq computational pipeline, see chex-pipeline.

Copyright

Copyright (c) 2017-2023, Youtao Lu, Kevin L. Bullaughey, Jean G. Rosario, C. Erik Nordgren, Stephen A. Fisher and Junhyong Kim, Department of Biology, University of Pennsylvania
Copyright (c) 2017-2023, Jaehee Lee, Jifen Li, Jinhui Wang, Hyun-Bum Kim and James Eberwine, Perelman School of Medicine, University of Pennsylvania

License

MPL-2

Reference

• Youtao Lu, Jaehee Lee, Jifen Li, Srinivasa Rao Allu, Jinhui Wang, Hyun-Bum Kim, Kevin L. Bullaughey, Stephen A. Fisher, C. Erik Nordgren, Jean G. Rosario, Stewart A. Anderson, Alexandra V. Ulyanova, Steven Brem, H. Isaac Chen, John A. Wolf, M. Sean Grady, Sergei A. Vinogradov, Junhyong Kim and James Eberwine. "CHEX-seq Detects Single-Cell Genomic Single-Strand DNA with Catalytical Potential." (Nature Communications 14, 7346 (2023))

Notes

• Due to GitHub space limit, most Data files (rds or big gz) and part of the Report files (per-sample coverage) are only available at Zenodo.