SIRS Criteria Calculator

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A modern web application for calculating Systemic Inflammatory Response Syndrome (SIRS) criteria, designed to assist healthcare professionals in rapid patient assessment and early sepsis detection.

I wrote this as a medical student at University of Massachusetts Medical School to lessen cognitive load and improve accuracy while seeing patients in the clinics.

What is SIRS?

Systemic Inflammatory Response Syndrome (SIRS) is a serious clinical condition that represents a body-wide inflammatory state. It is often a precursor to sepsis, a life-threatening condition that requires immediate medical attention. A patient is considered to have SIRS when they meet two or more of the following criteria:

• Temperature > 38.0°C (100.4°F) or < 36.0°C (96.8°F)
• Heart rate > 90 beats/minute
• Respiratory rate > 20 breaths/minute
• White blood cell count > 12,000/mm³ or < 4,000/mm³

Why is this Important?

Early detection of SIRS is crucial because:

• It can be an early warning sign of sepsis
• Quick intervention can significantly improve patient outcomes
• It helps standardize the assessment process
• It reduces the likelihood of missing critical cases
• It supports evidence-based medical decision making

Features

• Real-time SIRS Calculation: Instantly determine if SIRS criteria are met
• Detailed Criteria Breakdown: See which specific criteria were met
• Calculation History: Track and review previous calculations
• User-friendly Interface: Clean, intuitive design for rapid data entry
• Mobile Responsive: Use on any device at the bedside
• Data Persistence: Secure storage of calculations using Supabase
• Health Data Interoperability: Export results in FHIR and HL7 formats
  • FHIR: Export as FHIR Observation resources (JSON)
  • HL7: Export as HL7 v2.5.1 messages (Text)

Tech Stack

• Frontend: Javascript, HTML, CSS
• Backend: Node.js with Express
• Database: Supabase (PostgreSQL)
• Architecture: Clean Architecture with Domain-Driven Design
• Deployment: Vercel for serverless deployment
• Healthcare Standards: FHIR R4, HL7 v2.5.1

Healthcare Interoperability

The SIRS Calculator supports exporting assessment results in two widely-used healthcare interoperability standards:

FHIR (Fast Healthcare Interoperability Resources)

• Exports data as FHIR R4 Observation resources
• JSON format for modern API integration
• Includes standardized LOINC codes for SIRS assessment
• Structured data suitable for EHR integration

HL7 (Health Level 7)

• Exports data in HL7 v2.5.1 format
• Traditional text-based format widely used in healthcare
• Includes MSH, PID, OBR, and OBX segments
• Compatible with legacy healthcare systems

Contributing

We welcome contributions! Please feel free to submit a Pull Request.

License

This project is licensed under the MIT License - see the LICENSE file for details.