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BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 20 sequences circulating in Benelux #1247

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FedeGueli opened this issue Oct 22, 2022 · 7 comments
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@FedeGueli
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FedeGueli commented Oct 22, 2022

Here i want to propose another combo S:444/460.

This time it appeared in BA.5.2.7 (S:444M) .

Defining mutations

A28330G > C1627T > C27513T > C27012T > G12310A > C16616A > C17958T > T2058C > A22893T > T22942G
S:N460K (T22942G)

EDITED
Gisaid query: NSP2_M418T,Spike_K444M,Spike_N460K
finds 13 sequences

Number of sequences from Usher: 11

Expand for EPI_ISLs EPI_ISL_15250146 EPI_ISL_15223056 EPI_ISL_15285602 EPI_ISL_15313211 EPI_ISL_15433780 EPI_ISL_15422617 EPI_ISL_15285895 EPI_ISL_15216299 EPI_ISL_15374736 EPI_ISL_15175819

Countries:
Schermata 2022-10-22 alle 14 03 15

CovSpectrum: BA.5.2.7* (Nextclade) + S:N460K finds 10
https://cov-spectrum.org/explore/World/AllSamples/Past6M/variants?aaMutations=S%3AN460K&nextcladePangoLineage=BA.5.2.7*&aaMutations1=S%3A153I%2CS%3A1258Q%2CN%3A151L&

Tree:
Schermata 2022-10-22 alle 13 56 06

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_237c9_3aaa70.json?c=pango_lineage_usher&label=nuc%20mutations:T22942G

@FedeGueli FedeGueli changed the title BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 10 sequences circulating in Central Europe Oct 22, 2022
@corneliusroemer corneliusroemer added recommended Recommended for designation by pango team member BA.5 labels Oct 23, 2022
@FedeGueli FedeGueli changed the title BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 10 sequences circulating in Central Europe BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 13 sequences circulating in Central Europe Oct 23, 2022
@FedeGueli
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New query posted above finds 13 seqs.

@corneliusroemer corneliusroemer changed the title BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 13 sequences circulating in Central Europe BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 13 sequences circulating in Benelux Oct 24, 2022
@FedeGueli
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15 seqs now with NSP2_M418T,Spike_K444M,Spike_N460K :
The new sequences are from: one from Chile, one from Germany

@FedeGueli FedeGueli changed the title BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 13 sequences circulating in Benelux BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 15 sequences circulating in Benelux Oct 28, 2022
@FedeGueli FedeGueli changed the title BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 15 sequences circulating in Benelux BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 15 sequences circulating in Benelux Oct 28, 2022
@FedeGueli FedeGueli changed the title BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 15 sequences circulating in Benelux BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 17 sequences circulating in Benelux Oct 29, 2022
@FedeGueli
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Two more sequences from netherlands

@FedeGueli FedeGueli changed the title BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 17 sequences circulating in Benelux BA.5.2.7(S:K444M) sublineage with S:N460K (T22942G) 20 sequences circulating in Benelux Oct 30, 2022
@FedeGueli
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FedeGueli commented Oct 30, 2022

three more sequences from Luxembourg this is going quite fast @corneliusroemer

@InfrPopGen InfrPopGen self-assigned this Nov 1, 2022
InfrPopGen added a commit that referenced this issue Nov 1, 2022
Added new lineage CY.1 from #1247 with 3 new sequence designations, and 0 updated designations
@InfrPopGen InfrPopGen added this to the CY.1 milestone Nov 1, 2022
@InfrPopGen InfrPopGen added designated and removed recommended Recommended for designation by pango team member labels Nov 1, 2022
@InfrPopGen
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Thanks for submitting. We've added lineage CY.1 with 3 newly designated sequences, and 0 updated designations. Defining mutation T22942G (S:N460K) (following A22893T (S:K444M)).

@FedeGueli
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Thx @InfrPopGen !

@Mydtlwn
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Mydtlwn commented Nov 1, 2022

Is it not good that CY.1 in the file lineage_notes.txt is placed under CW? After all, CY.1 is a child of Ba.5.2.7, and there is a big difference between them.

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