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Add VO-DrugBank predictions and curations #159

Merged
merged 8 commits into from
Oct 10, 2023
Merged

Add VO-DrugBank predictions and curations #159

merged 8 commits into from
Oct 10, 2023

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cthoyt
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@cthoyt cthoyt commented Sep 27, 2023

  • First pass with canned workflow
  • Create a more custom workflow for doing lexical matchings, since a lot of the time, there are many components mapped to the upper level vaccine in DrugBank

For example, vo:0000015 (Boostrix), a booster immunization against tetanus, diphtheria and pertussis, gets mapped to the following:

  • drugbank:DB10583 Clostridium
  • drugbank:DB10584 Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)
  • drugbank:DB10788 Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)
  • drugbank:DB10789

This doesn't really make sense in Biomappings since these are part-whole relationships. VO has these to some extent, so maybe they can be used to identify the more specific parts.

@cthoyt cthoyt marked this pull request as draft September 27, 2023 12:27
@cthoyt cthoyt marked this pull request as ready for review October 10, 2023 18:20
@cthoyt cthoyt merged commit 5bf9bb7 into master Oct 10, 2023
@cthoyt cthoyt deleted the vo-drugbank branch October 10, 2023 18:22
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