Approaches to Study Neural Circuits
The class is now finished. All 12 lectures are recorded and available to watch. All course materials, including assigned readings and lecture slides, are under the "code" tab, or in the "View code" folder if you're on a mobile device.
We have done our best to ensure all of the course material is accurate, but any necessary corrections will be in each lecture folder. If there are any questions or problems, or if you note any inaccuracies or important omissions, email [email protected]
Lecture 1: Signals and data acquisition hardware (note: Lecture 1 is a little rough, but the subsequent ones are more polished) https://www.youtube.com/watch?v=3mldM94od3g
Lecture 2: Sampling, filtering, convolution, digital data formats https://www.youtube.com/watch?v=9MAQtmK0b14
Lecture 3: Electrophysiology 1 (the basics) https://www.youtube.com/watch?v=Z-SOnQ9v6M8
Lecture 4: Electrophysiology 2 (data preprocessing and spike sorting) https://www.youtube.com/watch?v=0iukrKY34y4
Lecture 5: Fluorescent proteins; genetically encoded sensors and actuators (e.g. GCaMP, optogenetics, chemogenetics) https://www.youtube.com/watch?v=ebC5FL1kY1w
Lecture 6: In vivo imaging from photometry to miniscopes https://www.youtube.com/watch?v=YG6w5lV0Lwg
Lecture 7: In vivo imaging: from images to data https://www.youtube.com/watch?v=9juDmbkAUmY
Lecture 8: Anatomical tracing techniques https://www.youtube.com/watch?v=HXJGraPHS6g
Lecture 9: Lesions, pharmacology, and genetic manipulations https://www.youtube.com/watch?v=rqWcUTQFOR0
Lecture 10: Genetic manipulations part 2; sequencing and analyses of gene expression, scRNA-seq https://www.youtube.com/watch?v=yOQ3vf7iaaQ
Lecture 11: High throughput microscopy and brain clearing https://www.youtube.com/watch?v=37hkOQP2zZQ
Lecture 12: Experimental design (new lecture added in 2024) https://www.youtube.com/watch?v=0VhXJMyT4Ik