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Applied modelling in drug development: flexible Bayesian regression modelling in Stan via brms

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(Bayesian) Applied Modelling in Drug Development (BAMDD)

Flexible Bayesian regression modelling in Stan via brms

About

This website contains materials that were developed to accompany a series of workshops held in the Analytics department at Novartis over 2022-2024, illustrating the utility of the R package brms for solving drug- development problems. In order to highlight the versatility of that package, we have developed a collection of case studies covering a diverse set of clinical and statistical questions that were addressed via Bayesian modelling with the brms package.

Requirements

  • quarto
  • cmdstanr and cmdstan (cmdstanr::install_cmdstan())
  • other R package dependencies (see Imports under the dummy DESCRIPTION file, devtools::install_deps())

Quickstart

Rendering the book from Quarto source can be done using the provided Makefile:

make website QUARTO_PROFILE=public

License

Code

The code is licensed under GPL-2 (LICENSE)

Materials

The book itself is licensed under CC BY 4.0 (docs/public/LICENSE)