Skip to content

NiklasRz/disease-gene-network

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

3 Commits
 
 
 
 
 
 
 
 
 
 

Repository files navigation

disease-gene-network

About

This is a script to investigate the networks of genes, diseases and drugs as part of an assigment for the Complex Systems 2 exercise at the Medical University of Vienna.

The assignment is as follows:

1

  • What are the macroscopic properties of the gene-gene and the disease-disease networks?
  • Which two genes are involved in the largest number of disorders?

2

  • how does the disease-disease network as a projection of the disease-drug network look like?
  • how does the drug disease-disease network relate to or differ from the genetic disease-disease comorbidity network?

To run:

  • create a python virtual environment (optional but recommended)
  • install the requirements with "pip3 install -r requirements.txt"
  • run with "python3 code/run.py"
  • results are in ./results

Data source

wget -O data/diseases.tsv http://www.complex-systems.meduniwien.ac.at/lectures/DiseaseGeneNet.txt
wget -O data/drugs.tsv https://www.dgidb.org/data/monthly_tsvs/2022-Feb/interactions.tsv

About

No description, website, or topics provided.

Resources

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published

Languages