Implementation of cross-calibration and precision analysis for HR-pQCT.
Mikolajewicz, N., Zimmermann, E. A., Rummler, M., Hosseinitabatabaei, S., Julien, C., Glorieux, F. H., ... & Willie, B. M. (2021). Multisite longitudinal calibration of HR-pQCT scanners and precision in osteogenesis imperfecta. Bone, 147, 115880.
https://pubmed.ncbi.nlm.nih.gov/33561589/
XcalRep (x-calibration & reproducibility) is an R implementation of methods used for cross-calibration and precision analysis of HR-pQCT It enables cross-calibration and precision analysis in R for single- and multi-centre studies, conducted at single or multiple timepoints. XcalRep was developed with intended use for HR-pQCT, however, it easily extends to other instruments which undergo routine calibration and reproducibility assessment.
The XcalRep package provides the following utilities:
- single and multi-site precision error calculation (CV and SD-based errors)
- reference site selection
- scanner cross-calibration
Additionally, the XcalRep package provides multiple visualization tools to evaluate scanner reproducibility.
Visit XcalRep package site for documentation and step-by-step tutorials/vignettes.
Firstly, please install or update the package devtools by running
install.packages("devtools")
Then the XcalRep can be installed via
library(devtools)
install_github(repo = "NMikolajewicz/XcalRep")
This project is licensed under the MIT License - see the LICENSE.md file for details
- Bettina Willie, Elizabeth Zimmermann