diff --git a/go/vt/sqlparser/ast.go b/go/vt/sqlparser/ast.go
index df3dfd75dd8..7881f24398a 100644
--- a/go/vt/sqlparser/ast.go
+++ b/go/vt/sqlparser/ast.go
@@ -2379,6 +2379,32 @@ func (node *ComparisonExpr) replace(from, to Expr) bool {
 	return replaceExprs(from, to, &node.Left, &node.Right, &node.Escape)
 }
 
+// IsImpossible returns true if the comparison in the expression can never evaluate to true.
+// Note that this is not currently exhaustive to ALL impossible comparisons.
+func (node *ComparisonExpr) IsImpossible() bool {
+	var left, right *SQLVal
+	var ok bool
+	if left, ok = node.Left.(*SQLVal); !ok {
+		return false
+	}
+	if right, ok = node.Right.(*SQLVal); !ok {
+		return false
+	}
+	if node.Operator == NotEqualStr && left.Type == right.Type {
+		if len(left.Val) != len(right.Val) {
+			return false
+		}
+
+		for i := range left.Val {
+			if left.Val[i] != right.Val[i] {
+				return false
+			}
+		}
+		return true
+	}
+	return false
+}
+
 // RangeCond represents a BETWEEN or a NOT BETWEEN expression.
 type RangeCond struct {
 	Operator string
diff --git a/go/vt/sqlparser/ast_test.go b/go/vt/sqlparser/ast_test.go
index 08bd05d96d8..cf66c254001 100644
--- a/go/vt/sqlparser/ast_test.go
+++ b/go/vt/sqlparser/ast_test.go
@@ -412,6 +412,35 @@ func TestIsAggregate(t *testing.T) {
 	}
 }
 
+func TestIsImpossible(t *testing.T) {
+	f := ComparisonExpr{
+		Operator: NotEqualStr,
+		Left:     newIntVal("1"),
+		Right:    newIntVal("1"),
+	}
+	if !f.IsImpossible() {
+		t.Error("IsImpossible: false, want true")
+	}
+
+	f = ComparisonExpr{
+		Operator: EqualStr,
+		Left:     newIntVal("1"),
+		Right:    newIntVal("1"),
+	}
+	if f.IsImpossible() {
+		t.Error("IsImpossible: true, want false")
+	}
+
+	f = ComparisonExpr{
+		Operator: NotEqualStr,
+		Left:     newIntVal("1"),
+		Right:    newIntVal("2"),
+	}
+	if f.IsImpossible() {
+		t.Error("IsImpossible: true, want false")
+	}
+}
+
 func TestReplaceExpr(t *testing.T) {
 	tcases := []struct {
 		in, out string
diff --git a/go/vt/vttablet/endtoend/queries_test.go b/go/vt/vttablet/endtoend/queries_test.go
index 56021b831da..f407e08b91f 100644
--- a/go/vt/vttablet/endtoend/queries_test.go
+++ b/go/vt/vttablet/endtoend/queries_test.go
@@ -1789,6 +1789,38 @@ func TestQueries(t *testing.T) {
 				},
 			},
 		},
+		&framework.MultiCase{
+			Name: "impossible queries",
+			Cases: []framework.Testable{
+				&framework.TestCase{
+					Name:  "specific column",
+					Query: "select eid from vitess_a where 1 != 1",
+					Rewritten: []string{
+						"select eid from vitess_a where 1 != 1",
+					},
+					RowsAffected: 0,
+				},
+				&framework.TestCase{
+					Name:  "all columns",
+					Query: "select * from vitess_a where 1 != 1",
+					Rewritten: []string{
+						"select * from vitess_a where 1 != 1",
+					},
+					RowsAffected: 0,
+				},
+				&framework.TestCase{
+					Name:  "bind vars",
+					Query: "select :bv from vitess_a where 1 != 1",
+					BindVars: map[string]*querypb.BindVariable{
+						"bv": sqltypes.Int64BindVariable(1),
+					},
+					Rewritten: []string{
+						"select 1 from vitess_a where 1 != 1 limit 10001",
+					},
+					RowsAffected: 0,
+				},
+			},
+		},
 	}
 	for _, tcase := range testCases {
 		if err := tcase.Test("", client); err != nil {
diff --git a/go/vt/vttablet/tabletserver/planbuilder/dml.go b/go/vt/vttablet/tabletserver/planbuilder/dml.go
index bdaed0ac5f8..c1cadcc4d73 100644
--- a/go/vt/vttablet/tabletserver/planbuilder/dml.go
+++ b/go/vt/vttablet/tabletserver/planbuilder/dml.go
@@ -202,6 +202,14 @@ func analyzeSelect(sel *sqlparser.Select, tables map[string]*schema.Table) (plan
 		return nil, err
 	}
 
+	if sel.Where != nil {
+		comp, ok := sel.Where.Expr.(*sqlparser.ComparisonExpr)
+		if ok && comp.IsImpossible() {
+			plan.PlanID = PlanSelectImpossible
+			return plan, nil
+		}
+	}
+
 	// Check if it's a NEXT VALUE statement.
 	if nextVal, ok := sel.SelectExprs[0].(sqlparser.Nextval); ok {
 		if table.Type != schema.Sequence {
diff --git a/go/vt/vttablet/tabletserver/planbuilder/plan.go b/go/vt/vttablet/tabletserver/planbuilder/plan.go
index bbeecd963ea..befeae05e40 100644
--- a/go/vt/vttablet/tabletserver/planbuilder/plan.go
+++ b/go/vt/vttablet/tabletserver/planbuilder/plan.go
@@ -83,6 +83,8 @@ const (
 	PlanOtherAdmin
 	// PlanMessageStream is used for streaming messages.
 	PlanMessageStream
+	// PlanSelectImpossible is used for where or having clauses that can never be true.
+	PlanSelectImpossible
 	// NumPlans stores the total number of plans
 	NumPlans
 )
@@ -105,6 +107,7 @@ var planName = [NumPlans]string{
 	"OTHER_READ",
 	"OTHER_ADMIN",
 	"MESSAGE_STREAM",
+	"SELECT_IMPOSSIBLE",
 }
 
 func (pt PlanType) String() string {
@@ -126,7 +129,7 @@ func PlanByName(s string) (pt PlanType, ok bool) {
 
 // IsSelect returns true if PlanType is about a select query.
 func (pt PlanType) IsSelect() bool {
-	return pt == PlanPassSelect || pt == PlanSelectLock
+	return pt == PlanPassSelect || pt == PlanSelectLock || pt == PlanSelectImpossible
 }
 
 // MarshalJSON returns a json string for PlanType.
@@ -140,22 +143,23 @@ func (pt PlanType) MinRole() tableacl.Role {
 }
 
 var tableACLRoles = map[PlanType]tableacl.Role{
-	PlanPassSelect:     tableacl.READER,
-	PlanSelectLock:     tableacl.READER,
-	PlanSet:            tableacl.READER,
-	PlanPassDML:        tableacl.WRITER,
-	PlanDMLPK:          tableacl.WRITER,
-	PlanDMLSubquery:    tableacl.WRITER,
-	PlanInsertPK:       tableacl.WRITER,
-	PlanInsertSubquery: tableacl.WRITER,
-	PlanInsertMessage:  tableacl.WRITER,
-	PlanDDL:            tableacl.ADMIN,
-	PlanSelectStream:   tableacl.READER,
-	PlanOtherRead:      tableacl.READER,
-	PlanOtherAdmin:     tableacl.ADMIN,
-	PlanUpsertPK:       tableacl.WRITER,
-	PlanNextval:        tableacl.WRITER,
-	PlanMessageStream:  tableacl.WRITER,
+	PlanPassSelect:       tableacl.READER,
+	PlanSelectLock:       tableacl.READER,
+	PlanSet:              tableacl.READER,
+	PlanPassDML:          tableacl.WRITER,
+	PlanDMLPK:            tableacl.WRITER,
+	PlanDMLSubquery:      tableacl.WRITER,
+	PlanInsertPK:         tableacl.WRITER,
+	PlanInsertSubquery:   tableacl.WRITER,
+	PlanInsertMessage:    tableacl.WRITER,
+	PlanDDL:              tableacl.ADMIN,
+	PlanSelectStream:     tableacl.READER,
+	PlanOtherRead:        tableacl.READER,
+	PlanOtherAdmin:       tableacl.ADMIN,
+	PlanUpsertPK:         tableacl.WRITER,
+	PlanNextval:          tableacl.WRITER,
+	PlanMessageStream:    tableacl.WRITER,
+	PlanSelectImpossible: tableacl.READER,
 }
 
 //_______________________________________________
diff --git a/go/vt/vttablet/tabletserver/query_executor.go b/go/vt/vttablet/tabletserver/query_executor.go
index 28b9c42eeec..6e8747e952c 100644
--- a/go/vt/vttablet/tabletserver/query_executor.go
+++ b/go/vt/vttablet/tabletserver/query_executor.go
@@ -106,6 +106,17 @@ func (qre *QueryExecutor) Execute() (reply *sqltypes.Result, err error) {
 		return qre.execDDL()
 	case planbuilder.PlanNextval:
 		return qre.execNextval()
+	case planbuilder.PlanSelectImpossible:
+		if qre.plan.Fields != nil {
+			return &sqltypes.Result{
+				Fields:       qre.plan.Fields,
+				RowsAffected: 0,
+				InsertID:     0,
+				Rows:         nil,
+				Extras:       nil,
+			}, nil
+		}
+		break
 	}
 
 	if qre.transactionID != 0 {
@@ -137,7 +148,7 @@ func (qre *QueryExecutor) Execute() (reply *sqltypes.Result, err error) {
 			return qre.execUpsertPK(conn)
 		case planbuilder.PlanSet:
 			return qre.txFetch(conn, qre.plan.FullQuery, qre.bindVars, nil, nil, true, true)
-		case planbuilder.PlanPassSelect, planbuilder.PlanSelectLock:
+		case planbuilder.PlanPassSelect, planbuilder.PlanSelectLock, planbuilder.PlanSelectImpossible:
 			return qre.execDirect(conn)
 		default:
 			// handled above:
@@ -151,7 +162,7 @@ func (qre *QueryExecutor) Execute() (reply *sqltypes.Result, err error) {
 		}
 	} else {
 		switch qre.plan.PlanID {
-		case planbuilder.PlanPassSelect:
+		case planbuilder.PlanPassSelect, planbuilder.PlanSelectImpossible:
 			return qre.execSelect()
 		case planbuilder.PlanSelectLock:
 			return nil, vterrors.Errorf(vtrpcpb.Code_FAILED_PRECONDITION, "%s disallowed outside transaction", qre.plan.PlanID.String())
diff --git a/go/vt/vttablet/tabletserver/query_executor_test.go b/go/vt/vttablet/tabletserver/query_executor_test.go
index 84ff6fd6016..334c026a28b 100644
--- a/go/vt/vttablet/tabletserver/query_executor_test.go
+++ b/go/vt/vttablet/tabletserver/query_executor_test.go
@@ -1242,6 +1242,31 @@ func TestQueryExecutorPlanPassSelect(t *testing.T) {
 	}
 }
 
+func TestQueryExecutorPlanSelectImpossible(t *testing.T) {
+	db := setUpQueryExecutorTest(t)
+	defer db.Close()
+	query := "select * from test_table where 1 != 1"
+	want := &sqltypes.Result{
+		Fields: getTestTableFields(),
+	}
+	db.AddQuery(query, want)
+	db.AddQuery("select * from test_table where 1 != 1", &sqltypes.Result{
+		Fields: getTestTableFields(),
+	})
+	ctx := context.Background()
+	tsv := newTestTabletServer(ctx, noFlags, db)
+	qre := newTestQueryExecutor(ctx, tsv, query, 0)
+	defer tsv.StopService()
+	checkPlanID(t, planbuilder.PlanSelectImpossible, qre.plan.PlanID)
+	got, err := qre.Execute()
+	if err != nil {
+		t.Fatalf("qre.Execute() = %v, want nil", err)
+	}
+	if !reflect.DeepEqual(got, want) {
+		t.Fatalf("got: %v, want: %v", got, want)
+	}
+}
+
 func TestQueryExecutorPlanPassSelectSqlSelectLimit(t *testing.T) {
 	db := setUpQueryExecutorTest(t)
 	defer db.Close()
@@ -1732,7 +1757,7 @@ func TestQueryExecutorTableAclDualTableExempt(t *testing.T) {
 	query := "select * from test_table where 1 != 1"
 	qre := newTestQueryExecutor(ctx, tsv, query, 0)
 	defer tsv.StopService()
-	checkPlanID(t, planbuilder.PlanPassSelect, qre.plan.PlanID)
+	checkPlanID(t, planbuilder.PlanSelectImpossible, qre.plan.PlanID)
 	// query should fail because nobody has read access to test_table
 	_, err := qre.Execute()
 	if code := vterrors.Code(err); code != vtrpcpb.Code_PERMISSION_DENIED {