diff --git a/download-data.sh b/download-data.sh
index bdd3239..8f736b0 100644
--- a/download-data.sh
+++ b/download-data.sh
@@ -14,6 +14,8 @@ export QUIET=${QUIET-0}
 export VERBOSE=${VERBOSE-0}
 # Dry-run mode.
 export DRY_RUN=${DRY_RUN-0}
+# No-verify-ssl mode: do not verify SSL certificates.
+export NO_VERIFY_SSL=${NO_VERIFY_SSL-0}
 # Download options: reduced-dev (default), reduced-exomes, full.
 export DOWNLOAD=${DOWNLOAD-reduced-dev}
 # Directory for static data.
@@ -21,14 +23,27 @@ export STATIC_INFIX=${STATIC_INFIX-varfish-static}
 # Overall directory prefix.
 export DIR_PREFIX=${DIR_PREFIX-.dev}
 # Overall static data directory.
-export DATA_DIR=${DATA_DIR-$DIR_PREFIX/volumes/$STATIC_INFIX/data}
+export DATA_DIR=${DATA_DIR-$DIR_PREFIX/volumes/$STATIC_DIR/data}
 # S3 endpoing URL.
 export S3_ENDPOINT_URL=https://ceph-s3-public.cubi.bihealth.org
+# Grep regex expression for downloading data.
+export LIST_GREP=${LIST_GREP-}
+# Steps to execute
+export STEPS=${STEPS-s3_sync,other}
+
+# Set S5CMD_NO_VERIFY_SSL_ARG based on NO_VERIFY_SSL
+if [ "$NO_VERIFY_SSL" -eq 1 ]; then
+    S5CMD_NO_VERIFY_SSL_ARG="--no-verify-ssl"
+else
+    S5CMD_NO_VERIFY_SSL_ARG=""
+fi
 
 # -- Versions -----------------------------------------------------------------
 
 # annonars
 export V_ANNONARS=${V_ANNONARS-0.33.0}
+# annonars for annonars/genes
+export V_ANNONARS_ANNONARS_GENES=${V_ANNONARS_ANNONARS_GENES-0.34.0}
 # viguno
 export V_VIGUNO=${V_VIGUNO-0.2.0}
 # VarFish Worker
@@ -63,6 +78,8 @@ export V_HPO=${V_HPO-20230606}
 export V_ORPHAPACKETS=${V_ORPHAPACKETS-10.1}
 # VarFish DB Download Data
 export V_VARFISHDB=${V_VARFISHDB-20240105}
+# VarFish DB Download Data for annonars/genes
+export V_VARFISHDB_ANNONARS_GENES=${V_VARFISHDB_ANNONARS_GENES-20240119}
 # gnomAD exomes GRCh37
 export V_GNOMAD_EXOMES_GRCH37=${V_GNOMAD_EXOMES_GRCH37-2.1.1}
 # gnomAD exomes GRCh38
@@ -200,10 +217,11 @@ run()
 
 # -- Downloading --------------------------------------------------------------
 
-log_info "Download data ..."
+if [[ "${STEPS}" = *s3_sync* ]]; then
+    log_info "Download data ..."
 
-# First, write out folders that we want to download.
-cat <<EOF >/tmp/download-list.txt
+    # First, write out folders that we want to download.
+    cat <<EOF >/tmp/download-list.raw.txt
 annonars/cadd-grch37-$V_CADD+$V_ANNONARS
 annonars/cadd-grch38-$V_CADD+$V_ANNONARS
 annonars/cons-grch37-$V_UCSC_CONS_37+$V_ANNONARS
@@ -216,7 +234,7 @@ annonars/dbsnp-grch37-$V_DBSNP+$V_ANNONARS
 annonars/dbsnp-grch38-$V_DBSNP+$V_ANNONARS
 annonars/functional-grch37-$V_REFSEQ_GRCH37+$V_ANNONARS
 annonars/functional-grch38-$V_REFSEQ_GRCH38+$V_ANNONARS
-annonars/genes-$V_ACMG_SF+$V_GNOMAD_CONSTRAINTS+$V_DBNSFP_NO_SUFFIX+$V_HPO+$V_ORPHAPACKETS+$V_VARFISHDB+$V_ANNONARS
+annonars/genes-$V_ACMG_SF+$V_GNOMAD_CONSTRAINTS+$V_DBNSFP_NO_SUFFIX+$V_HPO_ANNONARS_GENES+$V_VARFISHDB_ANNONARS_GENES+$V_ANNONARS_ANNONARS_GENES
 annonars/gnomad-exomes-grch37-$V_GNOMAD_EXOMES_GRCH37+$V_ANNONARS
 annonars/gnomad-exomes-grch38-$V_GNOMAD_EXOMES_GRCH38+$V_ANNONARS
 annonars/gnomad-genomes-grch37-$V_GNOMAD_EXOMES_GRCH37+$V_ANNONARS
@@ -238,373 +256,378 @@ tracks
 worker
 viguno/hpo-$V_HPO+$V_VIGUNO
 EOF
-# Create download directory.
-mkdir -p $DATA_DIR/download
-# Download each entry from download list.  Note that we support commenting
-# out lines with a leading "#".
-grep -v ^# /tmp/download-list.txt >/tmp/download-list.nocomment.txt
-while read -r line; do
-    # Create the download directory.
-    run mkdir -p $DATA_DIR/download/$line
-    # Actually download the data.
-    log_info "s3://varfish-public/$(prefix_for $line)/$line/* -> $DATA_DIR/download/$line"
-    run s5cmd \
-        --endpoint-url=$S3_ENDPOINT_URL \
-        --no-sign-request \
-        --no-verify-ssl \
-        sync \
-        "s3://varfish-public/$(prefix_for $line)/$line/*" \
-        $DATA_DIR/download/$line \
-    &> >(tee /tmp/download.stderr >&2)
-    grep ^ERROR /tmp/download.stderr >/dev/null && exit 1
-done </tmp/download-list.nocomment.txt
-
-log_info "... done downloading data."
-
-log_info "Setup symlink structure ..."
-
-log_info "- annonars"
-mkdir -p $DATA_DIR/annonars/{grch37,grch38}
-
-rm -f $DATA_DIR/annonars/genes
-ln -sr \
-    $DATA_DIR/download/annonars/genes-$V_ACMG_SF+$V_GNOMAD_CONSTRAINTS+$V_DBNSFP_NO_SUFFIX+$V_HPO+$V_ORPHAPACKETS+$V_VARFISHDB+$V_ANNONARS \
-    $DATA_DIR/annonars/genes
-
-# cadd - GRCh37
-rm -f $DATA_DIR/annonars/grch37/cadd
-ln -sr \
-    $DATA_DIR/download/annonars/cadd-grch37-$V_CADD+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/cadd
-# cadd - GRCh38
-rm -f $DATA_DIR/annonars/grch38/cadd
-ln -sr \
-    $DATA_DIR/download/annonars/cadd-grch38-$V_CADD+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/cadd
-
-# dbsnp - GRCh37
-rm -f $DATA_DIR/annonars/grch37/dbsnp
-ln -sr \
-    $DATA_DIR/download/annonars/dbsnp-grch37-$V_DBSNP+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/dbsnp
-# dbsnp - GRCh38
-rm -f $DATA_DIR/annonars/grch38/dbsnp
-ln -sr \
-    $DATA_DIR/download/annonars/dbsnp-grch38-$V_DBSNP+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/dbsnp
-
-# dbnsfp - GRCh37
-rm -f $DATA_DIR/annonars/grch37/dbnsfp
-ln -sr \
-    $DATA_DIR/download/annonars/dbnsfp-grch37-$V_DBNSFP+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/dbnsfp
-# dbnsfp - GRCh38
-rm -f $DATA_DIR/annonars/grch38/dbnsfp
-ln -sr \
-    $DATA_DIR/download/annonars/dbnsfp-grch38-$V_DBNSFP+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/dbnsfp
-
-# dbscsnv - GRCh37
-rm -f $DATA_DIR/annonars/grch37/dbscsnv
-ln -sr \
-    $DATA_DIR/download/annonars/dbscsnv-grch37-$V_DBSCSNV+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/dbscsnv
-# dbscsnv - GRCh38
-rm -f $DATA_DIR/annonars/grch38/dbscsnv
-ln -sr \
-    $DATA_DIR/download/annonars/dbscsnv-grch38-$V_DBSCSNV+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/dbscsnv
-
-# gnomad-mtdna - GRCh37
-rm -f $DATA_DIR/annonars/grch37/gnomad-mtdna
-ln -sr \
-    $DATA_DIR/download/annonars/gnomad-mtdna-grch37-$V_GNOMAD_MT+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/gnomad-mtdna
-# gnomad-mtdna - GRCh38
-rm -f $DATA_DIR/annonars/grch38/gnomad-mtdna
-ln -sr \
-    $DATA_DIR/download/annonars/gnomad-mtdna-grch38-$V_GNOMAD_MT+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/gnomad-mtdna
-
-# helixmtdb - GRCh37
-rm -f $DATA_DIR/annonars/grch37/helixmtdb
-ln -sr \
-    $DATA_DIR/download/annonars/helixmtdb-grch37-$V_HELIXMTDB+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/helixmtdb
-# helixmtdb - GRCh38
-rm -f $DATA_DIR/annonars/grch38/helixmtdb
-ln -sr \
-    $DATA_DIR/download/annonars/helixmtdb-grch38-$V_HELIXMTDB+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/helixmtdb
-
-# gnomad-genomes - GRCh37
-rm -f $DATA_DIR/annonars/grch37/gnomad-genomes
-ln -sr \
-    $DATA_DIR/download/annonars/gnomad-genomes-grch37-$V_GNOMAD_GENOMES_GRCH37+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/gnomad-genomes
-# gnomad-genomes - GRCh38
-rm -f $DATA_DIR/annonars/grch38/gnomad-genomes
-ln -sr \
-    $DATA_DIR/download/annonars/gnomad-genomes-grch38-$V_GNOMAD_GENOMES_GRCH38+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/gnomad-genomes
-
-# gnomad-exomes - GRCh37
-rm -f $DATA_DIR/annonars/grch37/gnomad-exomes
-ln -sr \
-    $DATA_DIR/download/annonars/gnomad-exomes-grch37-$V_GNOMAD_EXOMES_GRCH37+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/gnomad-exomes
-# gnomad-exomes - GRCh38
-rm -f $DATA_DIR/annonars/grch38/gnomad-exomes
-ln -sr \
-    $DATA_DIR/download/annonars/gnomad-exomes-grch38-$V_GNOMAD_EXOMES_GRCH38+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/gnomad-exomes
-
-# cons - GRCh37
-rm -f $DATA_DIR/annonars/grch37/cons
-ln -sr \
-    $DATA_DIR/download/annonars/cons-grch37-$V_UCSC_CONS_37+$V_ANNONARS \
-    $DATA_DIR/annonars/grch37/cons
-# cons - GRCh38
-rm -f $DATA_DIR/annonars/grch38/cons
-ln -sr \
-    $DATA_DIR/download/annonars/cons-grch38-$V_UCSC_CONS_38+$V_ANNONARS \
-    $DATA_DIR/annonars/grch38/cons
-
-log_info "- mehari"
-mkdir -p $DATA_DIR/mehari/{grch37,grch38}
-
-# freqs - GRCh37
-rm -f $DATA_DIR/mehari/grch37/freqs
-ln -sr \
-    $DATA_DIR/download/mehari/freqs-grch37-$V_GNOMAD_EXOMES_GRCH37+$V_GNOMAD_GENOMES_GRCH37+$V_GNOMAD_MT+$V_HELIXMTDB+$V_ANNONARS \
-    $DATA_DIR/mehari/grch37/freqs
-# freqs - GRCh38
-rm -f $DATA_DIR/mehari/grch38/freqs
-ln -sr \
-    $DATA_DIR/download/mehari/freqs-grch38-$V_GNOMAD_EXOMES_GRCH38+$V_GNOMAD_GENOMES_GRCH38+$V_GNOMAD_MT+$V_HELIXMTDB+$V_ANNONARS \
-    $DATA_DIR/mehari/grch38/freqs
-
-log_info "- viguno"
-mkdir -p $DATA_DIR/viguno
-
-# xlink
-rm -f $DATA_DIR/hgnc_xlink.tsv
-ln -sr \
-    $DATA_DIR/download/mehari/genes-xlink-$V_VARFISHDB/genes-xlink.tsv \
-    $DATA_DIR/hgnc_xlink.tsv
-# hpo
-rm -f $DATA_DIR/hpo
-ln -sr \
-    $DATA_DIR/download/viguno/hpo-$V_HPO+$V_VIGUNO \
-    $DATA_DIR/hpo
-
-log_info "- worker"
-mkdir -p $DATA_DIR/worker/grch3{7,8}/strucvars/bgdbs
-
-log_info "  - strucvars/bgdbs"
-rm -f $DATA_DIR/worker/grch3{7,8}/strucvars/bgdbs/{exac,g1k,gnomad,dbvar,dgv,dgv-gs}.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-dbvar-grch37-*/bgdb-dbvar.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/bgdbs/dbvar.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-dbvar-grch38-*/bgdb-dbvar.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/strucvars/bgdbs/dbvar.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-grch37-*/bgdb-dgv.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/bgdbs/dgv.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-grch38-*/bgdb-dgv.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/strucvars/bgdbs/dgv.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-gs-grch37-*/bgdb-dgv-gs.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/bgdbs/dgv_gs.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-gs-grch38-*/bgdb-dgv-gs.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/strucvars/bgdbs/dgv_gs.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-g1k-grch37-$V_G1K+$V_WORKER/bgdb-g1k.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/bgdbs/g1k.bin
-# NB: no thousand genomes for GRCh38
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-exac-grch37-*/bgdb-exac.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/bgdbs/gnomad_exomes.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-gnomad-exomes-cnv-grch38-*/bgdb-gnomad-exomes-cnv-grch38.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/strucvars/bgdbs/gnomad_exomes.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-gnomad-grch37-*/bgdb-gnomad.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/bgdbs/gnomad_genomes.bin
-ln -sr $(echo $DATA_DIR/download/worker/bgdb-gnomad-genomes-sv-grch38-*/bgdb-gnomad-genomes-sv-grch38.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/strucvars/bgdbs/gnomad_genomes.bin
-
-log_info "  - strucvars/clinvar"
-rm -f $DATA_DIR/worker/grch3{7,8}/strucvars/clinvar.bin
-
-ln -sr $(ls $DATA_DIR/download/worker/clinvar-strucvars-grch37-*/clinvar-strucvars.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/clinvar.bin
-ln -sr $(ls $DATA_DIR/download/worker/clinvar-strucvars-grch38-*/clinvar-strucvars.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/strucvars/clinvar.bin
-
-log_info "  - strucvars/patho_mms"
-rm -f $DATA_DIR/worker/grch3?/strucvars/patho_mms.bed
-
-ln -sr $(ls $DATA_DIR/download/worker/patho-mms-grch37-*/patho-mms.bed | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/strucvars/patho_mms.bed
-ln -sr $(ls $DATA_DIR/download/worker/patho-mms-grch38-*/patho-mms.bed | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/strucvars/patho_mms.bed
-
-log_info "  - strucvars/tads"
-mkdir -p $DATA_DIR/worker/grch3{7,8}/tads
-rm -f $DATA_DIR/worker/grch3?/tads/hesc.bed
-
-ln -sr $(ls $DATA_DIR/download/worker/tads-grch37-dixon2015/hesc.bed | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/tads/hesc.bed
-ln -sr $(ls $DATA_DIR/download/worker/tads-grch38-dixon2015/hesc.bed | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/tads/hesc.bed
-
-log_info "  - noref/genes"
-mkdir -p $DATA_DIR/worker/noref/genes
-rm -f $DATA_DIR/worker/noref/genes/{xlink.bin,acmg.tsv,mim2gene.tsv}
-
-ln -sr $(ls $DATA_DIR/download/worker/genes-xlink-*/genes-xlink.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/noref/genes/xlink.bin
-ln -sr $(ls $DATA_DIR/download/worker/acmg-sf-*/acmg_sf.tsv | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/noref/genes/acmg.tsv
-ln -sr $(ls $DATA_DIR/download/worker/mim2gene-*/mim2gene.tsv | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/noref/genes/mim2gene.tsv
-
-log_info "  - grch3{7,8}/regions"
-mkdir -p $DATA_DIR/worker/grch3{7,8}/genes
-rm -f $DATA_DIR/worker/grch3?/genes/{ensembl_genes.bin,refseq_genes.bin}
-
-ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch37-*/ensembl_genes.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/genes/ensembl_genes.bin
-ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch38-*/ensembl_genes.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/genes/ensembl_genes.bin
-
-ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch37-*/refseq_genes.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/genes/refseq_genes.bin
-ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch38-*/refseq_genes.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/genes/refseq_genes.bin
-
-log_info "  - grch3{7,8}/features"
-mkdir -p $DATA_DIR/worker/grch3{7,8}/features
-rm -f $DATA_DIR/worker/grch3?/features/{masked_repeat.bin,masked_segdup.bin}
-
-ln -sr $(ls $DATA_DIR/download/worker/masked-repeat-grch37-*/masked-repeat.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/features/masked_repeat.bin
-ln -sr $(ls $DATA_DIR/download/worker/masked-segdup-grch37-*/masked-segdup.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch37/features/masked_segdup.bin
-
-ln -sr $(ls $DATA_DIR/download/worker/masked-repeat-grch38-*/masked-repeat.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/features/masked_repeat.bin
-ln -sr $(ls $DATA_DIR/download/worker/masked-segdup-grch38-*/masked-segdup.bin | tr ' ' '\n' | tail -n 1) \
-  $DATA_DIR/worker/grch38/features/masked_segdup.bin
-
-log_info "- tracks"
-
-mkdir -p $DATA_DIR/nginx/grch3{7,8}
-rm -f $DATA_DIR/nginx/grch3{7,8}/*
-
-for release in grch37 grch38; do
-  paths_release=$(find $DATA_DIR/download/tracks/ -type f -name '*.bed' -or -name '*.bed.gz' | sort | grep $release)
-  for path in $paths_release; do
-    if [[ -e ${path}.tbi ]]; then
-      rm -f $DATA_DIR/nginx/$release/$(basename $path)
-      rm -f $DATA_DIR/nginx/$release/$(basename $path).tbi
-      ln -sr $path ${path}.tbi $DATA_DIR/nginx/$release
+    # Possibly limit download list
+    if [[ -z "$LIST_GREP" ]]; then
+        cp /tmp/download-list.raw.txt /tmp/download-list.txt
     else
-      rm -f $DATA_DIR/nginx/$release/$(basename $path)
-      ln -sr $path $DATA_DIR/nginx/$release
+        grep "$LIST_GREP" /tmp/download-list.raw.txt \
+        > /tmp/download-list.txt
     fi
-  done
-done
-
-log_info "... done setting up symlink structure."
-
-log_info "- mehari transcripts"
-
-mkdir -p $DATA_DIR/download/mehari-data-txs-grch3{7,8}
-
-for ext in .zst .zst.sha256 .zst.report .zst.report.sha256; do
-  for release in grch37 grch38; do
-    wget -q -c -O $DATA_DIR/download/mehari-data-txs-$release/mehari-data-txs-$release-$V_MEHARI_TXS.bin$ext \
-      https://github.com/varfish-org/mehari-data-tx/releases/download/v$V_MEHARI_TXS/mehari-data-txs-$release-$V_MEHARI_TXS.bin$ext
-  done
-done
-
-for release in grch37 grch38; do
-  rm -f $DATA_DIR/mehari/$release/txs.bin.zst
-  ln -sr $DATA_DIR/download/mehari-data-txs-$release/mehari-data-txs-$release-$V_MEHARI_TXS.bin.zst \
-    $DATA_DIR/mehari/$release/txs.bin.zst
-done
-
-log_info "- clinvar"
-
-wget -q -c -O /tmp/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
-  https://github.com/varfish-org/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-wget -q -c -O /tmp/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
-  https://github.com/varfish-org/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-
-tar -C $DATA_DIR/download/annonars/ \
-  -xf /tmp/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-tar -C $DATA_DIR/download/annonars \
-  -xf /tmp/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-
-rm -f $DATA_DIR/annonars/grch37/clinvar
-ln -sr $DATA_DIR/download/annonars/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
-  $DATA_DIR/annonars/grch37/clinvar
-rm -f $DATA_DIR/annonars/grch38/clinvar
-ln -sr $DATA_DIR/download/annonars/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
-  $DATA_DIR/annonars/grch38/clinvar
-
-wget -q -c -O /tmp/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
-  https://github.com/varfish-org/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-tar -C $DATA_DIR/download/annonars \
-  -xf /tmp/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-
-rm -f $DATA_DIR/annonars/clinvar-genes
-ln -sr $DATA_DIR/download/annonars/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
-  $DATA_DIR/annonars/clinvar-genes
-
-wget -q -c -O /tmp/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
-  https://github.com/varfish-org/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-wget -q -c -O /tmp/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
-  https://github.com/varfish-org/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-tar -C $DATA_DIR/download/annonars/ \
-  -xf /tmp/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-tar -C $DATA_DIR/download/annonars/ \
-  -xf /tmp/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
-rm -f $DATA_DIR/annonars/grch3{7,8}/clinvar-sv
-ln -sr $DATA_DIR/download/annonars/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
-  $DATA_DIR/annonars/grch37/clinvar-sv
-ln -sr $DATA_DIR/download/annonars/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
-  $DATA_DIR/annonars/grch38/clinvar-sv
-
-log_info "- dotty"
-
-mkdir -p $DATA_DIR/download/dotty
-pushd $DATA_DIR/download/dotty >/dev/null
-wget -q -c \
-    https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.ensembl.grch37.json.gz \
-    https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.ensembl.grch38.json.gz \
-    https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.refseq.grch37.json.gz \
-    https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.refseq.grch38.json.gz
-wget -q -c \
-  https://github.com/varfish-org/dotty/releases/download/v$V_DOTTY_SEQREPO/seqrepo.tar.gz-00 \
-  https://github.com/varfish-org/dotty/releases/download/v$V_DOTTY_SEQREPO/seqrepo.tar.gz-01
-cat seqrepo.tar.gz-?? | tar -xzf -
-popd >/dev/null
-
-mkdir -p $DATA_DIR/dotty
-rm -f $DATA_DIR/dotty/{*.json.gz,seqrepo}
-ln -sr $DATA_DIR/download/dotty/{*.json.gz,seqrepo} \
-  $DATA_DIR/dotty
-
-log_info "- cada-prio"
-
-mkdir -p $DATA_DIR/download/cada
-pushd $DATA_DIR/download/cada >/dev/null
-wget -q -c \
-    https://github.com/varfish-org/cada-prio-data/releases/download/cada-prio-data-$V_CADA_PRIO_MODEL/cada-prio-model-$V_CADA_PRIO_MODEL+$V_CADA_PRIO_VERSION.tar.gz
-tar -xzf cada-prio-model-$V_CADA_PRIO_MODEL+$V_CADA_PRIO_VERSION.tar.gz
-popd >/dev/null
-
-mkdir -p $DATA_DIR/cada
-rm -f $DATA_DIR/cada/model
-
-source_dir="$DATA_DIR/download/cada/cada-prio-model-$V_CADA_PRIO_MODEL+$V_CADA_PRIO_VERSION/model"
-for file in "${source_dir}"/*; do
-  rm -f "$DATA_DIR/cada/$(basename "$file")"
-  ln -sr "$file" "$DATA_DIR/cada/"
-done
+    # Create download directory.
+    mkdir -p $DATA_DIR/download
+    # Download each entry from download list.  Note that we support commenting
+    # out lines with a leading "#".
+    grep -v ^# /tmp/download-list.txt >/tmp/download-list.nocomment.txt
+    while read -r line; do
+        # Create the download directory.
+        run mkdir -p $DATA_DIR/download/$line
+        # Actually download the data.
+        log_info "s3://varfish-public/$(prefix_for $line)/$line/* -> $DATA_DIR/download/$line"
+        run s5cmd \
+            --endpoint-url=$S3_ENDPOINT_URL \
+            --no-sign-request \
+            $S5CMD_NO_VERIFY_SSL_ARG \
+            sync \
+            "s3://varfish-public/$(prefix_for $line)/$line/*" \
+            $DATA_DIR/download/$line \
+        &> >(tee /tmp/download.stderr >&2)
+        grep ^ERROR /tmp/download.stderr >/dev/null && exit 1
+    done </tmp/download-list.nocomment.txt
+
+    log_info "... done downloading data."
+
+    log_info "Setup symlink structure ..."
+
+    log_info "- annonars"
+    mkdir -p $DATA_DIR/annonars/{grch37,grch38}
+
+    rm -f $DATA_DIR/annonars/genes
+    ln -sr \
+        $DATA_DIR/download/annonars/genes-$V_ACMG_SF+$V_GNOMAD_CONSTRAINTS+$V_DBNSFP_NO_SUFFIX+$V_HPO_ANNONARS_GENES+$V_VARFISHDB_ANNONARS_GENES+$V_ANNONARS_ANNONARS_GENES \
+        $DATA_DIR/annonars/genes
+
+    # cadd - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/cadd
+    ln -sr \
+        $DATA_DIR/download/annonars/cadd-grch37-$V_CADD+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/cadd
+    # cadd - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/cadd
+    ln -sr \
+        $DATA_DIR/download/annonars/cadd-grch38-$V_CADD+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/cadd
+
+    # dbsnp - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/dbsnp
+    ln -sr \
+        $DATA_DIR/download/annonars/dbsnp-grch37-$V_DBSNP+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/dbsnp
+    # dbsnp - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/dbsnp
+    ln -sr \
+        $DATA_DIR/download/annonars/dbsnp-grch38-$V_DBSNP+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/dbsnp
+
+    # dbnsfp - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/dbnsfp
+    ln -sr \
+        $DATA_DIR/download/annonars/dbnsfp-grch37-$V_DBNSFP+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/dbnsfp
+    # dbnsfp - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/dbnsfp
+    ln -sr \
+        $DATA_DIR/download/annonars/dbnsfp-grch38-$V_DBNSFP+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/dbnsfp
+
+    # dbscsnv - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/dbscsnv
+    ln -sr \
+        $DATA_DIR/download/annonars/dbscsnv-grch37-$V_DBSCSNV+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/dbscsnv
+    # dbscsnv - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/dbscsnv
+    ln -sr \
+        $DATA_DIR/download/annonars/dbscsnv-grch38-$V_DBSCSNV+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/dbscsnv
+
+    # gnomad-mtdna - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/gnomad-mtdna
+    ln -sr \
+        $DATA_DIR/download/annonars/gnomad-mtdna-grch37-$V_GNOMAD_MT+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/gnomad-mtdna
+    # gnomad-mtdna - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/gnomad-mtdna
+    ln -sr \
+        $DATA_DIR/download/annonars/gnomad-mtdna-grch38-$V_GNOMAD_MT+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/gnomad-mtdna
+
+    # helixmtdb - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/helixmtdb
+    ln -sr \
+        $DATA_DIR/download/annonars/helixmtdb-grch37-$V_HELIXMTDB+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/helixmtdb
+    # helixmtdb - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/helixmtdb
+    ln -sr \
+        $DATA_DIR/download/annonars/helixmtdb-grch38-$V_HELIXMTDB+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/helixmtdb
+
+    # gnomad-genomes - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/gnomad-genomes
+    ln -sr \
+        $DATA_DIR/download/annonars/gnomad-genomes-grch37-$V_GNOMAD_GENOMES_GRCH37+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/gnomad-genomes
+    # gnomad-genomes - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/gnomad-genomes
+    ln -sr \
+        $DATA_DIR/download/annonars/gnomad-genomes-grch38-$V_GNOMAD_GENOMES_GRCH38+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/gnomad-genomes
+
+    # gnomad-exomes - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/gnomad-exomes
+    ln -sr \
+        $DATA_DIR/download/annonars/gnomad-exomes-grch37-$V_GNOMAD_EXOMES_GRCH37+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/gnomad-exomes
+    # gnomad-exomes - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/gnomad-exomes
+    ln -sr \
+        $DATA_DIR/download/annonars/gnomad-exomes-grch38-$V_GNOMAD_EXOMES_GRCH38+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/gnomad-exomes
+
+    # cons - GRCh37
+    rm -f $DATA_DIR/annonars/grch37/cons
+    ln -sr \
+        $DATA_DIR/download/annonars/cons-grch37-$V_UCSC_CONS_37+$V_ANNONARS \
+        $DATA_DIR/annonars/grch37/cons
+    # cons - GRCh38
+    rm -f $DATA_DIR/annonars/grch38/cons
+    ln -sr \
+        $DATA_DIR/download/annonars/cons-grch38-$V_UCSC_CONS_38+$V_ANNONARS \
+        $DATA_DIR/annonars/grch38/cons
+
+    log_info "- mehari"
+    mkdir -p $DATA_DIR/mehari/{grch37,grch38}
+
+    # freqs - GRCh37
+    rm -f $DATA_DIR/mehari/grch37/freqs
+    ln -sr \
+        $DATA_DIR/download/mehari/freqs-grch37-$V_GNOMAD_EXOMES_GRCH37+$V_GNOMAD_GENOMES_GRCH37+$V_GNOMAD_MT+$V_HELIXMTDB+$V_ANNONARS \
+        $DATA_DIR/mehari/grch37/freqs
+    # freqs - GRCh38
+    rm -f $DATA_DIR/mehari/grch38/freqs
+    ln -sr \
+        $DATA_DIR/download/mehari/freqs-grch38-$V_GNOMAD_EXOMES_GRCH38+$V_GNOMAD_GENOMES_GRCH38+$V_GNOMAD_MT+$V_HELIXMTDB+$V_ANNONARS \
+        $DATA_DIR/mehari/grch38/freqs
+
+    log_info "- viguno"
+    mkdir -p $DATA_DIR/viguno
+
+    # xlink
+    rm -f $DATA_DIR/hgnc_xlink.tsv
+    ln -sr \
+        $DATA_DIR/download/mehari/genes-xlink-$V_VARFISHDB/genes-xlink.tsv \
+        $DATA_DIR/hgnc_xlink.tsv
+    # hpo
+    rm -f $DATA_DIR/hpo
+    ln -sr \
+        $DATA_DIR/download/viguno/hpo-$V_HPO+$V_VIGUNO \
+        $DATA_DIR/hpo
+
+    log_info "- worker"
+    mkdir -p $DATA_DIR/worker/grch3{7,8}/strucvars/bgdbs
+
+    log_info "  - strucvars/bgdbs"
+    rm -f $DATA_DIR/worker/grch3{7,8}/strucvars/bgdbs/{exac,g1k,gnomad,dbvar,dgv,dgv-gs}.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-exac-grch37-*/bgdb-exac.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/bgdbs/exac.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-g1k-grch37-$V_G1K+$V_WORKER/bgdb-g1k.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/bgdbs/g1k.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-gnomad-grch37-*/bgdb-gnomad.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/bgdbs/gnomad.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-dbvar-grch37-*/bgdb-dbvar.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/bgdbs/dbvar.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-dbvar-grch38-*/bgdb-dbvar.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/strucvars/bgdbs/dbvar.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-grch37-*/bgdb-dgv.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/bgdbs/dgv.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-grch38-*/bgdb-dgv.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/strucvars/bgdbs/dgv.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-gs-grch37-*/bgdb-dgv-gs.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/bgdbs/dgv-gs.bin
+    ln -sr $(echo $DATA_DIR/download/worker/bgdb-dgv-gs-grch38-*/bgdb-dgv-gs.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/strucvars/bgdbs/dgv-gs.bin
+
+    log_info "  - strucvars/clinvar"
+    rm -f $DATA_DIR/worker/grch3{7,8}/strucvars/clinvar.bin
+
+    ln -sr $(ls $DATA_DIR/download/worker/clinvar-strucvars-grch37-*/clinvar-strucvars.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/clinvar.bin
+    ln -sr $(ls $DATA_DIR/download/worker/clinvar-strucvars-grch38-*/clinvar-strucvars.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/strucvars/clinvar.bin
+
+    log_info "  - strucvars/patho-mms"
+    rm -f $DATA_DIR/worker/grch3?/strucvars/patho-mms.bed
+
+    ln -sr $(ls $DATA_DIR/download/worker/patho-mms-grch37-*/patho-mms.bed | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/strucvars/patho-mms.bed
+    ln -sr $(ls $DATA_DIR/download/worker/patho-mms-grch38-*/patho-mms.bed | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/strucvars/patho-mms.bed
+
+    log_info "  - strucvars/tads"
+    mkdir -p $DATA_DIR/worker/grch3{7,8}/tads
+    rm -f $DATA_DIR/worker/grch3?/tads/hesc.bed
+
+    ln -sr $(ls $DATA_DIR/download/worker/tads-grch37-dixon2015/hesc.bed | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/tads/hesc.bed
+    ln -sr $(ls $DATA_DIR/download/worker/tads-grch38-dixon2015/hesc.bed | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/tads/hesc.bed
+
+    log_info "  - noref/genes"
+    mkdir -p $DATA_DIR/worker/noref/genes
+    rm -f $DATA_DIR/worker/noref/genes/{xlink.bin,acmg.tsv,mime2gene.tsv}
+
+    ln -sr $(ls $DATA_DIR/download/worker/genes-xlink-*/genes-xlink.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/noref/genes/xlink.bin
+    ln -sr $(ls $DATA_DIR/download/worker/acmg-sf-*/acmg_sf.tsv | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/noref/genes/acmg.tsv
+    ln -sr $(ls $DATA_DIR/download/worker/mim2gene-*/mim2gene.tsv | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/noref/genes/mime2gene.tsv
+
+    log_info "  - grch3{7,8}/regions"
+    mkdir -p $DATA_DIR/worker/grch3{7,8}/genes
+    rm -f $DATA_DIR/worker/grch3?/genes/{ensembl_genes.bin,refseq_genes.bin}
+
+    ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch37-*/ensembl_genes.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/genes/ensembl_genes.bin
+    ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch38-*/ensembl_genes.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/genes/ensembl_genes.bin
+
+    ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch37-*/refseq_genes.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/genes/refseq_genes.bin
+    ln -sr $(ls $DATA_DIR/download/worker/genes-regions-grch38-*/refseq_genes.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/genes/refseq_genes.bin
+
+    log_info "  - grch3{7,8}/features"
+    mkdir -p $DATA_DIR/worker/grch3{7,8}/features
+    rm -f $DATA_DIR/worker/grch3?/features/{masked_repeat.bin,masked_seqdup.bin}
+
+    ln -sr $(ls $DATA_DIR/download/worker/masked-repeat-grch37-*/masked-repeat.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/features/masked_repeat.bin
+    ln -sr $(ls $DATA_DIR/download/worker/masked-segdup-grch37-*/masked-segdup.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch37/features/masked_seqdup.bin
+
+    ln -sr $(ls $DATA_DIR/download/worker/masked-repeat-grch38-*/masked-repeat.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/features/masked_repeat.bin
+    ln -sr $(ls $DATA_DIR/download/worker/masked-segdup-grch38-*/masked-segdup.bin | tr ' ' '\n' | tail -n 1) \
+      $DATA_DIR/worker/grch38/features/masked_seqdup.bin
+
+    log_info "- tracks"
+
+    mkdir -p $DATA_DIR/nginx/grch3{7,8}
+    rm -f $DATA_DIR/nginx/grch3{7,8}/*
+
+    for release in grch37 grch38; do
+      paths_release=$(find $DATA_DIR/download/tracks/ -type f -name '*.bed' -or -name '*.bed.gz' | sort | grep $release)
+      for path in $paths_release; do
+        if [[ -e ${path}.tbi ]]; then
+          rm -f $DATA_DIR/nginx/$release/$(basename $path)
+          rm -f $DATA_DIR/nginx/$release/$(basename $path).tbi
+          ln -sr $path ${path}.tbi $DATA_DIR/nginx/$release
+        else
+          rm -f $DATA_DIR/nginx/$release/$(basename $path)
+          ln -sr $path $DATA_DIR/nginx/$release
+        fi
+      done
+    done
+
+    log_info "... done setting up symlink structure."
+fi
+
+if [[ "$STEPS" = *other* ]]; then
+    log_info "- mehari transcripts"
+
+    mkdir -p $DATA_DIR/download/mehari-data-txs-grch3{7,8}
+
+    for ext in .zst .zst.sha256 .zst.report .zst.report.sha256; do
+      for release in grch37 grch38; do
+        wget -q -c -O $DATA_DIR/download/mehari-data-txs-$release/mehari-data-txs-$release-$V_MEHARI_TXS.bin$ext \
+          https://github.com/bihealth/mehari-data-tx/releases/download/v$V_MEHARI_TXS/mehari-data-txs-$release-$V_MEHARI_TXS.bin$ext
+      done
+    done
+
+    for release in grch37 grch38; do
+      rm -f $DATA_DIR/mehari/$release/txs.bin.zst
+      ln -sr $DATA_DIR/download/mehari-data-txs-$release/mehari-data-txs-$release-$V_MEHARI_TXS.bin.zst \
+        $DATA_DIR/mehari/$release/txs.bin.zst
+    done
+
+    log_info "- clinvar"
+
+    wget -q -c -O /tmp/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
+      https://github.com/bihealth/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+    wget -q -c -O /tmp/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
+      https://github.com/bihealth/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+
+    tar -C $DATA_DIR/download/annonars/ \
+      -xf /tmp/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+    tar -C $DATA_DIR/download/annonars \
+      -xf /tmp/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+
+    rm -f $DATA_DIR/annonars/grch37/clinvar
+    ln -sr $DATA_DIR/download/annonars/annonars-clinvar-minimal-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
+      $DATA_DIR/annonars/grch37/clinvar
+    rm -f $DATA_DIR/annonars/grch38/clinvar
+    ln -sr $DATA_DIR/download/annonars/annonars-clinvar-minimal-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
+      $DATA_DIR/annonars/grch38/clinvar
+
+    wget -q -c -O /tmp/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
+      https://github.com/bihealth/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+    tar -C $DATA_DIR/download/annonars \
+      -xf /tmp/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+
+    rm -f $DATA_DIR/annonars/clinvar-genes
+    ln -sr $DATA_DIR/download/annonars/annonars-clinvar-genes-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
+      $DATA_DIR/annonars/clinvar-genes
+
+    wget -q -c -O /tmp/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
+      https://github.com/bihealth/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+    wget -q -c -O /tmp/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz \
+      https://github.com/bihealth/annonars-data-clinvar/releases/download/annonars-data-clinvar-$V_ANNONARS_DATA_CLINVAR_CLINVAR/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+    tar -C $DATA_DIR/download/annonars/ \
+      -xf /tmp/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+    tar -C $DATA_DIR/download/annonars/ \
+      -xf /tmp/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS.tar.gz
+    rm -f $DATA_DIR/annonars/grch3{7,8}/clinvar-sv
+    ln -sr $DATA_DIR/download/annonars/annonars-clinvar-sv-grch37-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
+      $DATA_DIR/annonars/grch37/clinvar-sv
+    ln -sr $DATA_DIR/download/annonars/annonars-clinvar-sv-grch38-$V_ANNONARS_DATA_CLINVAR_CLINVAR+$V_ANNONARS_DATA_CLINVAR_ANNONARS \
+      $DATA_DIR/annonars/grch38/clinvar-sv
+
+    log_info "- dotty"
+
+    mkdir -p $DIR_PREFIX/volumes/$STATIC_DIR/data/download/dotty
+    pushd $DIR_PREFIX/volumes/$STATIC_DIR/data/download/dotty >/dev/null
+    wget -q -c \
+        https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.ensembl.grch37.json.gz \
+        https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.ensembl.grch38.json.gz \
+        https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.refseq.grch37.json.gz \
+        https://github.com/SACGF/cdot/releases/download/v$V_DOTTY_CDOT_VERSION/cdot-$V_DOTTY_CDOT_VERSION.refseq.grch38.json.gz
+    wget -q -c \
+      https://github.com/bihealth/dotty/releases/download/v$V_DOTTY_SEQREPO/seqrepo.tar.gz-00 \
+      https://github.com/bihealth/dotty/releases/download/v$V_DOTTY_SEQREPO/seqrepo.tar.gz-01
+    cat seqrepo.tar.gz-?? | tar -xzf -
+    popd >/dev/null
+
+    mkdir -p $DIR_PREFIX/volumes/$STATIC_DIR/data/dotty
+    rm -f $DIR_PREFIX/volumes/$STATIC_DIR/data/dotty/{*.json.gz,seqrepo}
+    ln -sr $DIR_PREFIX/volumes/$STATIC_DIR/data/download/dotty/{*.json.gz,seqrepo} \
+      $DIR_PREFIX/volumes/$STATIC_DIR/data/dotty
+
+    log_info "- cada-prio"
+
+    mkdir -p $DIR_PREFIX/volumes/$STATIC_DIR/data/download/cada
+    pushd $DIR_PREFIX/volumes/$STATIC_DIR/data/download/cada >/dev/null
+    wget -q -c \
+        https://github.com/bihealth/cada-prio-data/releases/download/cada-prio-data-$V_CADA_PRIO_MODEL/cada-prio-model-$V_CADA_PRIO_MODEL+$V_CADA_PRIO_VERSION.tar.gz
+    tar -xzf cada-prio-model-$V_CADA_PRIO_MODEL+$V_CADA_PRIO_VERSION.tar.gz
+    popd >/dev/null
+
+    mkdir -p $DIR_PREFIX/volumes/$STATIC_DIR/data/cada
+    rm -f $DIR_PREFIX/volumes/$STATIC_DIR/data/cada/model
+
+    source_dir="$DIR_PREFIX/volumes/$STATIC_DIR/data/download/cada/cada-prio-model-$V_CADA_PRIO_MODEL+$V_CADA_PRIO_VERSION/model"
+    for file in "${source_dir}"/*; do
+      rm -f "$DIR_PREFIX/volumes/$STATIC_DIR/data/cada/$(basename "$file")"
+      ln -sr "$file" "$DIR_PREFIX/volumes/$STATIC_DIR/data/cada/"
+    done
+fi