diff --git a/CVO/cvo.owl b/CVO/cvo.owl index 0f8e94f..0f96a4a 100644 --- a/CVO/cvo.owl +++ b/CVO/cvo.owl @@ -16,7 +16,7 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - + en Chris mungall Erica Marcos @@ -62,7 +62,7 @@ OWL-DL Vaccine Ontology Cancer Vaccine View - 2024-11-23 + 2024-12-29 @@ -6122,6 +6122,21 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population. + + quality + PATO:0000169 + + + viability + + + + @@ -6654,6 +6669,38 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + + + + + + + + + + + + + + + + + + A vaccine that uses RNA(s) derived from a pathogen organism. + Using RNA may eliminate the problem of having to tailor a vaccine for each individual patient with their specific immunity. The advantage of RNA is that it can be used for all immunity types and can be taken from a single cell. DNA vaccines need to produce RNA which then prompts the manufacture of proteins. However, RNA vaccine eliminates the step from DNA to RNA. + Oliver He + mRNA vaccine + https://en.wikipedia.org/wiki/RNA_vaccine + vaccine + RNA vaccine + + + + @@ -6696,6 +6743,19 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + an organismal quality of a whole organism vaccine where the whole organism is inactivated/killed and lacks the capability of replication. + Oliver He + vaccine organism killed + quality + vaccine organism inactivated + + + + @@ -6723,6 +6783,37 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + + + + + + + + + + + + + + + + + + A whole organism vaccine that uses an inativated pathogen organism as its component. + Oliver He + inactivated organism vaccine + killed vaccine + vaccine + inactivated vaccine + + + + @@ -7045,7 +7136,7 @@ https://sourceforge.net/p/obi/obi-terms/738/ - A process that results in an adaptive immune response to one or more antigens. + Process that results in an adaptive immune response to one or more antigens. Allen Xiang Anna Maria Masci Barry Smith @@ -7080,7 +7171,7 @@ https://sourceforge.net/p/obi/obi-terms/738/ - + @@ -7140,7 +7231,7 @@ https://sourceforge.net/p/obi/obi-terms/738/ - disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease. + Process that prevents a disorder that is the physical basis of a disease. Allen Xiang Oliver He process @@ -7153,7 +7244,7 @@ https://sourceforge.net/p/obi/obi-terms/738/ - disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease. + Process that leads to treat a disorder that is the physical basis of a disease. Allen Xiang Oliver He process @@ -7262,6 +7353,35 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + + + + + + + + + + + + + + + + + + A vaccine containing a toxoid, used to protect against toxins produced by certain bacteria. A toxoid (also called inactivated toxin) is a processed toxin that has been treated by chemical means, heat, or irradiation and is no longer capable of causing disease. + Oliver He + vaccine + toxoid vaccine + + + + @@ -7623,6 +7743,60 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + + + + + + + + + + + + + + + + + + + a viral vaccine that is inactivated + killed viral vaccine + vaccine + inactivated viral vaccine + + + + + + + + + A vaccine role that indicates the vaccine being a RNA vaccine. + Oliver He + role + RNA vaccine role + + + + + + + + + A vaccine role that indicates the vaccine being a toxoid vaccine. + Oliver He + role + toxoid vaccine role + + + + @@ -7777,6 +7951,49 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + vaccine viability is a viability of a vaccine organism. + Allen Xiang + Oliver He + quality + vaccine organism viability + + + + + + + + + + + + + + + + + + + + + + + + + + + a bacterial vaccine that uses inactivated bacterial organism. + Oliver He + vaccine + inactivated bacterial vaccine + + + + @@ -8173,6 +8390,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -8181,6 +8399,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -8208,6 +8432,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -8215,6 +8440,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -8241,6 +8472,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -8250,6 +8482,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -8295,6 +8533,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -8302,6 +8541,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -8363,12 +8608,19 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + @@ -10002,6 +10254,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -10010,6 +10263,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -10113,6 +10372,8 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + @@ -10120,6 +10381,18 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + + + + + + @@ -10427,10 +10700,57 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + A vaccine role that inheres in a vaccine using virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines. + Anthony Huffman + Oliver He + virus like particle vaccine role + https://pubmed.ncbi.nlm.nih.gov/20923267/ + role + virus-like particle vaccine role + + + + + + + + + + + + + + + + + + + + + + + + + + A vaccine that uses virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines. + Anthony Huffman + Oliver He + virus like particle vaccine + https://pubmed.ncbi.nlm.nih.gov/20923267/ + vaccine + virus-like particle vaccine + + + + - + @@ -10442,7 +10762,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have - + @@ -12377,6 +12697,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -12392,6 +12713,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -12425,6 +12752,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -12440,6 +12768,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -13856,19 +14190,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have - - - - - - - @@ -15965,6 +16292,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -15980,6 +16308,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -16021,6 +16355,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -16030,6 +16365,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -16540,6 +16881,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -16548,6 +16890,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -18330,7 +18678,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have - + @@ -18342,7 +18690,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have - + @@ -18383,6 +18731,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -18398,6 +18747,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -19023,6 +19378,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -19038,6 +19394,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -19332,6 +19694,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -19347,6 +19710,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -20599,6 +20968,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -20614,6 +20984,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -22874,6 +23250,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -22888,6 +23265,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -24187,6 +24570,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -24202,6 +24586,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -24558,6 +24948,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -24572,6 +24963,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -24604,6 +25001,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -24618,6 +25016,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -25381,6 +25785,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -25396,6 +25801,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -25523,6 +25934,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -25538,6 +25950,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -25832,6 +26250,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -25847,6 +26266,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -26383,12 +26808,19 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + @@ -26478,6 +26910,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -26486,6 +26919,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -26805,12 +27244,19 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + @@ -26892,6 +27338,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -26907,6 +27354,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -27957,6 +28410,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -27970,6 +28424,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -28050,6 +28510,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -28065,6 +28526,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -28239,6 +28706,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -28254,6 +28722,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -28287,6 +28761,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -28302,6 +28777,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -29881,6 +30362,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -29889,6 +30371,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -30128,6 +30616,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -30142,6 +30631,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -30258,6 +30753,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -30265,6 +30761,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -30335,6 +30837,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -30342,6 +30845,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -30939,6 +31448,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -30949,6 +31459,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -31257,6 +31773,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -31265,6 +31782,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -32002,12 +32525,19 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + @@ -32151,6 +32681,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have + @@ -32158,6 +32689,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -34146,6 +34683,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -34154,6 +34692,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -34857,6 +35401,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -34865,6 +35410,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -35595,6 +36146,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -35602,6 +36154,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -35900,6 +36458,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -35907,6 +36466,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -35940,6 +36505,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -35947,6 +36513,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -36171,6 +36743,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -36179,6 +36752,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -36204,6 +36783,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -36212,6 +36792,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -36578,6 +37164,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -36585,6 +37172,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -38177,6 +38770,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -38184,6 +38778,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -38520,6 +39120,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -38533,6 +39134,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + diff --git a/CVX-VO/cvx-vo.owl b/CVX-VO/cvx-vo.owl index 66dc933..657453b 100644 --- a/CVX-VO/cvx-vo.owl +++ b/CVX-VO/cvx-vo.owl @@ -17,7 +17,7 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - + en Jie Zheng Yongqun "Oliver" He (YH) @@ -26,7 +26,7 @@ OWL-DL Vaccine Ontology CVX code View - 2024-11-23 + 2024-12-29 @@ -7952,6 +7952,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -7988,6 +7989,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -8406,6 +8413,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -8436,6 +8444,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -8622,6 +8636,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -8664,6 +8679,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -8825,6 +8846,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -8845,6 +8867,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -8926,6 +8954,38 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + + + + + + + + + + + + + + + + + A vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing the whole of parts of genes encoding one or more vaccine antigen proteins. + Oliver He + genetic vaccine + naked DNA vaccine + nucleic acid vaccine + vaccine + DNA vaccine + + + + @@ -9803,6 +9863,7 @@ http://biotech.about.com/b/2008/09/03/gardasil-safety-of-genetically-engineered- + @@ -9845,6 +9906,12 @@ http://biotech.about.com/b/2008/09/03/gardasil-safety-of-genetically-engineered- + + + + + + @@ -10997,11 +11064,8 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou - - - @@ -11082,6 +11146,12 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou + + + + + + @@ -11976,6 +12046,7 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou + @@ -11984,6 +12055,12 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou + + + + + + @@ -12357,7 +12434,6 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou - @@ -12498,7 +12574,6 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou - @@ -13323,6 +13398,13 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a + + + + + + + a Varicella-zoster virus vaccine that is live attenuated. Oliver He vaccine @@ -13669,7 +13751,14 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a + + + + + + + @@ -13699,7 +13788,7 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a - A process that results in an adaptive immune response to one or more antigens. + Process that results in an adaptive immune response to one or more antigens. Allen Xiang Anna Maria Masci Barry Smith @@ -13734,7 +13823,7 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a - + @@ -13794,7 +13883,7 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a - disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease. + Process that prevents a disorder that is the physical basis of a disease. Allen Xiang Oliver He process @@ -13807,7 +13896,7 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a - disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease. + Process that leads to treat a disorder that is the physical basis of a disease. Allen Xiang Oliver He process @@ -13848,7 +13937,14 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a + + + + + + + a diphtheria vaccine that uses diphtheria toxoid Oliver He vaccine @@ -14342,6 +14438,18 @@ http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&a + + + + + A vaccine role that indicates the vaccine being a DNA vaccine. + Oliver He + role + DNA vaccine role + + + + @@ -17685,6 +17793,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + a subunit vaccine that uses polysaccharide as protective antigen Oliver He vaccine @@ -19807,7 +19921,14 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + @@ -19836,6 +19957,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -19859,13 +19986,26 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + + + + + + + @@ -19885,6 +20025,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + vaccine Bordetella pertussis filamentous hemagglutinin vaccine, inactivated @@ -19895,6 +20041,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -20636,6 +20788,12 @@ over. + + + + + + @@ -20671,7 +20829,14 @@ over. + + + + + + + vaccine Streptococcus pneumoniae capsular antigen diphtheria CRM197 protein conjugate vaccine @@ -21099,6 +21264,12 @@ over. + + + + + + @@ -21129,6 +21300,12 @@ over. + + + + + + @@ -21159,6 +21336,12 @@ over. + + + + + + @@ -21189,6 +21372,12 @@ over. + + + + + + @@ -21219,6 +21408,12 @@ over. + + + + + + @@ -21249,6 +21444,12 @@ over. + + + + + + @@ -21279,6 +21480,12 @@ over. + + + + + + @@ -21309,6 +21516,12 @@ over. + + + + + + @@ -21339,6 +21552,12 @@ over. + + + + + + @@ -21369,6 +21588,12 @@ over. + + + + + + @@ -21399,6 +21624,12 @@ over. + + + + + + @@ -21429,6 +21660,12 @@ over. + + + + + + @@ -21459,6 +21696,12 @@ over. + + + + + + @@ -21664,6 +21907,7 @@ over. + @@ -21671,6 +21915,12 @@ over. + + + + + + @@ -21690,14 +21940,27 @@ over. + + + + + + + + + + + + + @@ -21719,7 +21982,14 @@ over. + + + + + + + A clostridium tetani vaccine that consists of formaldehyde inactivated tetanospasmin (aka tetanus toxoid). Hector Guzman-Orozco Oliver He @@ -21733,6 +22003,7 @@ over. + @@ -21741,6 +22012,12 @@ over. + + + + + + @@ -21911,13 +22188,26 @@ over. + + + + + + + + + + + + + @@ -22321,6 +22611,13 @@ over. + + + + + + + @@ -22353,6 +22650,12 @@ over. + + + + + + @@ -22432,6 +22735,12 @@ over. + + + + + + @@ -23173,6 +23482,7 @@ over. + @@ -23198,12 +23508,24 @@ over. + + + + + + + + + + + + @@ -23967,6 +24289,7 @@ over. + @@ -23992,12 +24315,24 @@ over. + + + + + + + + + + + + @@ -26264,7 +26599,14 @@ over. + + + + + + + @@ -26292,6 +26634,12 @@ over. + + + + + + @@ -26324,6 +26672,12 @@ over. + + + + + + @@ -26356,6 +26710,12 @@ over. + + + + + + @@ -27290,7 +27650,14 @@ over. + + + + + + + @@ -27322,6 +27689,12 @@ over. + + + + + + @@ -27410,7 +27783,14 @@ over. + + + + + + + @@ -27546,7 +27926,14 @@ over. + + + + + + + @@ -27741,6 +28128,12 @@ over. + + + + + + @@ -27849,6 +28242,12 @@ over. + + + + + + @@ -27887,6 +28286,12 @@ over. + + + + + + @@ -29164,6 +29569,12 @@ over. + + + + + + Oliver He Philip Huang Rohit Goru @@ -29177,6 +29588,12 @@ over. + + + + + + Oliver He Philip Huang Rohit Goru @@ -29189,7 +29606,14 @@ over. + + + + + + + Oliver He Philip Huang Rohit Goru @@ -29220,7 +29644,14 @@ over. + + + + + + + Philip Huang vaccine COVID-19 DNA vaccine @@ -29231,7 +29662,14 @@ over. + + + + + + + Philip Huang vaccine COVID-19 live, attenuated vaccine @@ -29243,6 +29681,13 @@ over. + + + + + + + Philip Huang vaccine COVID-19 virus-like particle vaccine @@ -29330,6 +29775,12 @@ over. + + + + + + @@ -29360,6 +29811,12 @@ over. + + + + + + @@ -29390,6 +29847,12 @@ over. + + + + + + @@ -29419,6 +29882,12 @@ over. + + + + + + @@ -29450,6 +29919,12 @@ over. + + + + + + @@ -29480,6 +29955,12 @@ over. + + + + + + @@ -30045,6 +30526,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -30055,6 +30537,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -30120,6 +30608,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -30133,6 +30622,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -30153,6 +30648,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -30161,6 +30657,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -30327,6 +30829,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -30362,6 +30870,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -30372,6 +30881,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -30406,6 +30921,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -30421,6 +30937,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -30449,6 +30971,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -30464,6 +30987,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -30486,7 +31015,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -30528,24 +31064,46 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + + + + + + + + + @@ -30931,7 +31489,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -30964,7 +31529,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -30997,7 +31569,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -31162,6 +31741,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -31169,6 +31749,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -31738,7 +32324,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -31804,13 +32397,27 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + @@ -31837,7 +32444,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -31939,12 +32553,12 @@ administered prior to exposure or within two weeks after exposure. - + - + @@ -32013,7 +32627,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -32046,7 +32667,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -32079,7 +32707,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -32112,7 +32747,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -32333,7 +32975,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -32366,7 +33015,20 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + @@ -32399,7 +33061,20 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + @@ -32432,7 +33107,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -32465,6 +33147,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32497,6 +33185,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32529,6 +33223,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32561,6 +33261,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32593,6 +33299,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32625,6 +33337,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32657,6 +33375,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32689,6 +33413,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32721,6 +33451,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32753,6 +33489,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32785,6 +33527,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32817,6 +33565,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32881,7 +33635,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -32915,6 +33676,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -32981,6 +33748,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -33014,6 +33787,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -33047,6 +33826,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -33145,6 +33930,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -33152,6 +33938,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -33178,6 +33970,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -33185,6 +33978,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -33245,7 +34044,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33279,7 +34085,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33346,7 +34159,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33379,7 +34199,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33412,7 +34239,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33511,7 +34345,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33579,7 +34420,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33757,6 +34605,36 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + + + + + + + + + A cancer vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing the whole of parts of genes encoding one or more vaccine antigen proteins. + Jie Zheng + cancer vaccine + DNA cancer vaccine + + + + @@ -33799,14 +34677,28 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + @@ -33826,8 +34718,15 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33908,6 +34807,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -33939,7 +34844,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -33971,7 +34883,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34003,7 +34922,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34035,7 +34961,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34067,7 +35000,20 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + @@ -34099,13 +35045,34 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + + + + + + + + @@ -34126,7 +35093,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34353,6 +35327,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -34362,6 +35337,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -34382,6 +35363,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -34391,6 +35373,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -34411,6 +35399,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -34418,6 +35407,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -34439,12 +35434,24 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + @@ -34465,13 +35472,32 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + + + + + + @@ -34492,18 +35518,40 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + + + + + + + + + @@ -34524,18 +35572,40 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + + + + + + + + + @@ -34556,9 +35626,16 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34585,7 +35662,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34612,8 +35696,15 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34639,7 +35730,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -34749,6 +35847,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -34756,6 +35855,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -34857,7 +35962,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35081,7 +36193,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35108,6 +36227,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -35115,6 +36235,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -35169,6 +36295,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -35189,7 +36321,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35216,7 +36355,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35243,6 +36389,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -35250,6 +36397,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -35405,7 +36558,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35459,7 +36619,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35566,13 +36733,27 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + @@ -35593,13 +36774,27 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + @@ -35620,13 +36815,27 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + @@ -35647,6 +36856,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -35654,6 +36864,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -35674,6 +36890,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -35681,6 +36898,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -35783,7 +37006,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35810,7 +37040,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35972,7 +37209,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -35999,13 +37243,26 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + @@ -36061,6 +37318,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -36137,6 +37400,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -36145,6 +37409,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -36220,7 +37490,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -36247,7 +37524,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -39959,7 +41243,9 @@ administered prior to exposure or within two weeks after exposure. + + @@ -39979,6 +41265,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -39991,6 +41283,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -40931,7 +42229,6 @@ immunogen: ROT - @@ -41238,7 +42535,7 @@ immunogen: ROT - + @@ -41414,12 +42711,30 @@ immunogen: ROT + + + + + + + + + + + + + + + + + + @@ -41438,15 +42753,36 @@ immunogen: ROT + + + + + + + + + + + + + + + + + + + + + @@ -41469,7 +42805,14 @@ immunogen: ROT + + + + + + + @@ -41498,7 +42841,14 @@ immunogen: ROT + + + + + + + @@ -41774,7 +43124,6 @@ immunogen: ROT - @@ -42306,7 +43655,6 @@ immunogen: ROT - @@ -48267,7 +49615,6 @@ immunogen: ROT - @@ -48412,6 +49759,12 @@ immunogen: ROT + + + + + + @@ -48454,6 +49807,12 @@ immunogen: ROT + + + + + + diff --git a/robot_report.tsv b/robot_report.tsv index ff5cf6e..4b0c54c 100644 --- a/robot_report.tsv +++ b/robot_report.tsv @@ -160,6 +160,7 @@ WARN annotation_whitespace VO:0000794 IAO:0000115 A Brucella abortus gene that h WARN annotation_whitespace VO:0000799 IAO:0000115 "An object property that represents a mutational relation between a vaccine organism and another material (e.g., gene or protein). the mutated material initially exists in the original wildtype organism. " WARN annotation_whitespace VO:0000807 IAO:0000115 A vaccine role that indicates the vaccine being a toxoid vaccine. WARN annotation_whitespace VO:0000818 IAO:0000115 An object property that specifies a relation between a vaccine and a vaccine virmugen. +WARN annotation_whitespace VO:0000857 IAO:0000115 "Process profile that is measurable and the measured data indicates the degree of immunological protection in the vaccine recipient. More specifically, it is the process in some immune response component (such as gene, protein, etc.) which serves as an immune biomarker. " WARN annotation_whitespace VO:0000922 IAO:0000115 a vaccine stablizer that is based on monosodium glutamate. WARN annotation_whitespace VO:0000929 rdfs:comment "Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Reference: http://www.sciencelab.com/msds.php?msdsId=9926640 " WARN annotation_whitespace VO:0000931 IAO:0000115 a cell culture residual in vaccine that is residual protein from cell culture. @@ -503,6 +504,8 @@ WARN equivalent_class_axiom_no_genus OBI:0000673 OBI:0000417 OBI:0000675 WARN equivalent_class_axiom_no_genus OBI:0000838 OBI:0000417 OBI:0000806 WARN equivalent_class_axiom_no_genus OBI:0200000 OBI:0000417 OBI:0200166 WARN equivalent_class_axiom_no_genus OBI:1110034 RO:0000087 OBI:0000237 +WARN equivalent_class_axiom_no_genus OPMI:0000445 RO:0000087 OPMI:0000441 +WARN missing_definition BFO:0000133 IAO:0000115 WARN missing_definition BFO:0000141 IAO:0000115 WARN missing_definition CHEBI:30911 IAO:0000115 WARN missing_definition CHEBI:33130 IAO:0000115 @@ -1039,6 +1042,8 @@ WARN missing_definition OGG:3000888751 IAO:0000115 WARN missing_definition OGG:3000888772 IAO:0000115 WARN missing_definition OGG:3001197075 IAO:0000115 WARN missing_definition OGMS:0000060 IAO:0000115 +WARN missing_definition OPMI:0000441 IAO:0000115 +WARN missing_definition OPMI:0000446 IAO:0000115 WARN missing_definition RO:0002086 IAO:0000115 WARN missing_definition RO:0002091 IAO:0000115 WARN missing_definition RO:0002092 IAO:0000115 @@ -1231,7 +1236,6 @@ WARN missing_definition VO:0000304 IAO:0000115 WARN missing_definition VO:0000305 IAO:0000115 WARN missing_definition VO:0000306 IAO:0000115 WARN missing_definition VO:0000308 IAO:0000115 -WARN missing_definition VO:0000309 IAO:0000115 WARN missing_definition VO:0000311 IAO:0000115 WARN missing_definition VO:0000312 IAO:0000115 WARN missing_definition VO:0000313 IAO:0000115 @@ -1428,7 +1432,6 @@ WARN missing_definition VO:0000843 IAO:0000115 WARN missing_definition VO:0000844 IAO:0000115 WARN missing_definition VO:0000845 IAO:0000115 WARN missing_definition VO:0000852 IAO:0000115 -WARN missing_definition VO:0000857 IAO:0000115 WARN missing_definition VO:0000863 IAO:0000115 WARN missing_definition VO:0000866 IAO:0000115 WARN missing_definition VO:0000870 IAO:0000115 @@ -1493,7 +1496,6 @@ WARN missing_definition VO:0001016 IAO:0000115 WARN missing_definition VO:0001020 IAO:0000115 WARN missing_definition VO:0001026 IAO:0000115 WARN missing_definition VO:0001029 IAO:0000115 -WARN missing_definition VO:0001030 IAO:0000115 WARN missing_definition VO:0001033 IAO:0000115 WARN missing_definition VO:0001042 IAO:0000115 WARN missing_definition VO:0001049 IAO:0000115 @@ -2932,30 +2934,22 @@ WARN missing_definition VO:0003012 IAO:0000115 WARN missing_definition VO:0003013 IAO:0000115 WARN missing_definition VO:0003014 IAO:0000115 WARN missing_definition VO:0003032 IAO:0000115 -WARN missing_definition VO:0003045 IAO:0000115 WARN missing_definition VO:0003051 IAO:0000115 WARN missing_definition VO:0003053 IAO:0000115 -WARN missing_definition VO:0003063 IAO:0000115 -WARN missing_definition VO:0003064 IAO:0000115 -WARN missing_definition VO:0003065 IAO:0000115 WARN missing_definition VO:0003066 IAO:0000115 WARN missing_definition VO:0003067 IAO:0000115 -WARN missing_definition VO:0003068 IAO:0000115 WARN missing_definition VO:0003070 IAO:0000115 WARN missing_definition VO:0003071 IAO:0000115 WARN missing_definition VO:0003072 IAO:0000115 WARN missing_definition VO:0003073 IAO:0000115 WARN missing_definition VO:0003074 IAO:0000115 WARN missing_definition VO:0003075 IAO:0000115 -WARN missing_definition VO:0003077 IAO:0000115 WARN missing_definition VO:0003080 IAO:0000115 WARN missing_definition VO:0003081 IAO:0000115 WARN missing_definition VO:0003082 IAO:0000115 WARN missing_definition VO:0003083 IAO:0000115 WARN missing_definition VO:0003084 IAO:0000115 WARN missing_definition VO:0003085 IAO:0000115 -WARN missing_definition VO:0003086 IAO:0000115 -WARN missing_definition VO:0003087 IAO:0000115 WARN missing_definition VO:0003088 IAO:0000115 WARN missing_definition VO:0003094 IAO:0000115 WARN missing_definition VO:0003104 IAO:0000115 @@ -4679,7 +4673,6 @@ WARN missing_definition VO:0005300 IAO:0000115 WARN missing_definition VO:0005301 IAO:0000115 WARN missing_definition VO:0005302 IAO:0000115 WARN missing_definition VO:0005303 IAO:0000115 -WARN missing_definition VO:0005308 IAO:0000115 WARN missing_definition VO:0005323 IAO:0000115 WARN missing_definition VO:0005330 IAO:0000115 WARN missing_definition VO:0005379 IAO:0000115 @@ -5132,6 +5125,18 @@ WARN missing_definition VO:0010432 IAO:0000115 WARN missing_definition VO:0010433 IAO:0000115 WARN missing_definition VO:0010457 IAO:0000115 WARN missing_definition VO:0010460 IAO:0000115 +WARN missing_definition VO:0010461 IAO:0000115 +WARN missing_definition VO:0010462 IAO:0000115 +WARN missing_definition VO:0010465 IAO:0000115 +WARN missing_definition VO:0010466 IAO:0000115 +WARN missing_definition VO:0010467 IAO:0000115 +WARN missing_definition VO:0010468 IAO:0000115 +WARN missing_definition VO:0010469 IAO:0000115 +WARN missing_definition VO:0010470 IAO:0000115 +WARN missing_definition VO:0010471 IAO:0000115 +WARN missing_definition VO:0010472 IAO:0000115 +WARN missing_definition VO:0010473 IAO:0000115 +WARN missing_definition VO:0010474 IAO:0000115 WARN missing_definition VO:0010632 IAO:0000115 WARN missing_definition VO:0010705 IAO:0000115 WARN missing_definition VO:0010706 IAO:0000115 @@ -11875,6 +11880,7 @@ WARN missing_subset_declaration blank node rdfs:subPropertyOf WARN missing_subset_declaration blank node rdfs:subPropertyOf WARN missing_subset_declaration blank node rdfs:subPropertyOf WARN missing_subset_declaration blank node rdfs:subPropertyOf +WARN missing_subset_declaration blank node rdfs:subPropertyOf INFO lowercase_definition BFO:0000004 IAO:0000115 b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])@en INFO lowercase_definition BFO:0000015 IAO:0000115 "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])@en" INFO lowercase_definition BFO:0000016 IAO:0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])@en" @@ -12005,9 +12011,7 @@ INFO lowercase_definition VO:0000228 IAO:0000115 a vaccine component that contai INFO lowercase_definition VO:0000243 IAO:0000115 assay of CFU reduction in spleen is a CFU reduction assay that is measured using the extracted spleen as the tissue for isolation of infected pathogens. INFO lowercase_definition VO:0000263 IAO:0000115 sodBFt is a live vaccine strain mutant of Francisella tularensis with reduced Fe-superoxide dismutase gene expression. Ref: PMID:18692537. INFO lowercase_definition VO:0000283 IAO:0000115 a viral vaccine vector that uses a herpesvirus as the vector. -INFO lowercase_definition VO:0000288 IAO:0000115 a processual entity that specifies host response to a vaccine. INFO lowercase_definition VO:0000289 IAO:0000115 a process that specifies host response to a vaccine adjuvant. -INFO lowercase_definition VO:0000290 IAO:0000115 a processual entity that specifies host response to a vaccine component. INFO lowercase_definition VO:0000291 IAO:0000115 a process that specifies host response to a vaccine antigen. INFO lowercase_definition VO:0000292 IAO:0000115 a process that specifies host response to a vaccine vector. INFO lowercase_definition VO:0000310 IAO:0000115 a vaccine additive that stabilizes the vaccine emulsification manufacturing process and makes emulsion of the vaccine easier. @@ -12050,8 +12054,6 @@ INFO lowercase_definition VO:0000487 IAO:0000115 a S. typhi vaccine that is live INFO lowercase_definition VO:0000489 IAO:0000115 a licensed vaccine role that is bears in a licensed human vaccine. INFO lowercase_definition VO:0000493 IAO:0000115 natural active immunization is an active immunization that occur naturally when a person or animal comes in contact with antigens includeing microbes. INFO lowercase_definition VO:0000495 IAO:0000115 "induction of adaptive immune response to antigen is an active immunization process that results in induction of adaptive immune response to some antigens, for example, in a vaccine." -INFO lowercase_definition VO:0000496 IAO:0000115 disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease. -INFO lowercase_definition VO:0000497 IAO:0000115 disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease. INFO lowercase_definition VO:0000498 IAO:0000115 "modification of adaptive immune response to antigen is an active immunization process that results in modification of an adaptive immune response to some antigens, for example, in a therapeutic vaccine." INFO lowercase_definition VO:0000500 IAO:0000115 infection disorder prevention is a process that prevents a disorder that is the physical basis of an infectious disease. INFO lowercase_definition VO:0000504 IAO:0000115 a vaccine role that indicates the vaccine being a whole organism vaccine. @@ -12193,7 +12195,6 @@ INFO lowercase_definition VO:0001088 IAO:0000115 a viral vaccine vector that use INFO lowercase_definition VO:0001093 IAO:0000115 a vaccinia vaccine vector that uses the highly attenuated NYVAC as vector INFO lowercase_definition VO:0001095 IAO:0000115 "passive immunization by injecting a recipient with pre-made antibody, antitoxin, epitope, etc." INFO lowercase_definition VO:0001102 IAO:0000115 a viral vaccine vector that uses a retroviral strain -INFO lowercase_definition VO:0001103 IAO:0000115 inactivation is a processual entity that produces inactive material. INFO lowercase_definition VO:0001105 IAO:0000115 a bacterial vaccine against Lawsonia intracellularis infection INFO lowercase_definition VO:0001106 IAO:0000115 a poxvirus vaccine vector that uses a swinepox virus as the vector INFO lowercase_definition VO:0001107 IAO:0000115 a vaccinia virus vector that uses the Modified Vaccinia Ankara (MVA) virus. @@ -12203,8 +12204,6 @@ INFO lowercase_definition VO:0001110 IAO:0000115 a fertility vaccine that enhanc INFO lowercase_definition VO:0001112 IAO:0000115 a viral vaccine vector that uses a bovine parainfluenza virus strain as vector INFO lowercase_definition VO:0001114 IAO:0000115 a Bordetella bacterial vaccine against infection of B. avium INFO lowercase_definition VO:0001115 IAO:0000115 a poxvirus vaccine vector that uses an attenuated capripoxvirus strain as the vaccine vector -INFO lowercase_definition VO:0001116 IAO:0000115 survival of live vaccine inside host is a processual entity that represents the survival of a live vaccine inside its host. The time of the survival is often important for the success of the live vaccine. -INFO lowercase_definition VO:0001117 IAO:0000115 persistence of vaccine induced immune response is a processual entity that indicates the persistence of an immune reponse induced by a vaccine in a vaccinated host. INFO lowercase_definition VO:0001118 IAO:0000115 a bacterial vaccine vector that uses a Corynebacterium pseudotuberculosis strain as the vaccine vector INFO lowercase_definition VO:0001121 IAO:0000115 a viral vaccine vector that uses a rhabdovirus-based viral strain as the vaccine vector INFO lowercase_definition VO:0001122 IAO:0000115 a recombinant vaccine vector that uses Saccharomyces cerevisiae as the vaccine vector @@ -12340,7 +12339,7 @@ INFO lowercase_definition VO:0003026 IAO:0000115 "a role inheres in vaccine comp INFO lowercase_definition VO:0003027 IAO:0000115 a protein vaccine stablizer that is specifically human serum albumin. INFO lowercase_definition VO:0003028 IAO:0000115 the serum albumin that is part of human INFO lowercase_definition VO:0003029 IAO:0000115 a vaccine stabilizer that is gelatin. -INFO lowercase_definition VO:0003031 IAO:0000115 a vaccine-induced host gene response that represents a vaccine adverse event response associated with a host susceptibility gene. +INFO lowercase_definition VO:0003031 IAO:0000115 a vaccine-induced gene response that represents a vaccine adverse event response associated with a host susceptibility gene. INFO lowercase_definition VO:0003033 IAO:0000115 a protein vaccine stablizer that is specifically bovine serum albumin. INFO lowercase_definition VO:0003034 IAO:0000115 a vaccine stabilizer that is specifically made by a sugar. INFO lowercase_definition VO:0003035 IAO:0000115 a vaccine stabilizer that is generated based on amino acids. diff --git a/vo.owl b/vo.owl index 83bcc5e..da2f535 100644 --- a/vo.owl +++ b/vo.owl @@ -19,7 +19,7 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - + en Chris mungall Erica Marcos @@ -66,7 +66,7 @@ An ontology in the domain of vaccine and vaccination Vaccine Ontology - 2024-11-23 + 2024-12-29 @@ -2088,6 +2088,17 @@ A continuant cannot have an occurrent as part: use 'participates in'. + + + + + + + process profile of + + + + @@ -26945,6 +26956,53 @@ https://sourceforge.net/p/obi/obi-terms/738/ + + + + + Yingtong Liu, Anthony Huffman, Oliver He + + biomarker role + + + + + + + + + + + + + + + A material entity that has a measurable quality or process profile(s), which can be used as an indicator of an underlying biological state or identity. + The NIH Biomarkers and Surrogate Endpoint Working Group defined a biomarker as “A characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention” (https://pubmed.ncbi.nlm.nih.gov/11240971/). However, the definition of 'characteriistc' is unclear, so we do not use the exact definintion in the ontology. + Yingtong Liu, Anthony Huffman, Oliver He + https://en.wikipedia.org/wiki/Biomarker + https://en.wikipedia.org/wiki/Biomarker_(cell) + https://en.wikipedia.org/wiki/Biomarker_(medicine) + + biomarker + + + + + + + + + Anthony Huffman, Oliver He + A biomarker that is indicative of an immune response + https://pubmed.ncbi.nlm.nih.gov/22072636/ + https://pubmed.ncbi.nlm.nih.gov/32286245/ + + immune biomarker + + + + @@ -29116,6 +29174,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -29152,6 +29211,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -29429,7 +29494,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced lymphocyte activation @@ -29440,7 +29505,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced B cell antigen processing and presentation @@ -29451,7 +29516,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced B cell cytokine production @@ -29472,9 +29537,9 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& - + Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced B cell mediated immunity @@ -29632,6 +29697,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -29662,6 +29728,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -29789,6 +29861,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -30120,6 +30198,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -30162,6 +30241,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -30323,6 +30408,7 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + @@ -30343,6 +30429,12 @@ Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157& + + + + + + @@ -31658,6 +31750,7 @@ http://biotech.about.com/b/2008/09/03/gardasil-safety-of-genetically-engineered- + @@ -31700,6 +31793,12 @@ http://biotech.about.com/b/2008/09/03/gardasil-safety-of-genetically-engineered- + + + + + + @@ -33285,11 +33384,8 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou - - - @@ -33370,6 +33466,12 @@ influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an ou + + + + + + @@ -34511,10 +34613,10 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h - + Oliver He https://academic.oup.com/cid/article/32/1/76/311106 - vaccine-induced host response + vaccine-induced response T helper type 1 (Th1) lymphocytes secrete secrete interleukin (IL)-2, interferon-γ, and lymphotoxin-α and stimulate type 1 immunity, which is characterized by intense phagocytic activity. https://academic.oup.com/cid/article/32/1/76/311106 vaccine-induced T-helper 1 type immune response @@ -34524,10 +34626,10 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h - + Oliver He https://academic.oup.com/cid/article/32/1/76/311106 - vaccine-induced host response + vaccine-induced response Th2 cells secrete IL-4, IL-5, IL-9, IL-10, and IL-13 and stimulate type 2 immunity, which is characterized by high antibody titers. https://academic.oup.com/cid/article/32/1/76/311106 vaccine-induced T-helper 2 type immune response @@ -34551,6 +34653,7 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h + @@ -34559,6 +34662,12 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h + + + + + + @@ -34818,9 +34927,9 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h - + Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced T cell mediated immunity @@ -34831,7 +34940,7 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h Oliver He - vaccine-induced host response + vaccine-induced response T cell vaccine antigen processing and presentation @@ -34869,6 +34978,7 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h + @@ -34883,6 +34993,12 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h + + + + + + @@ -34932,6 +35048,7 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h + @@ -34941,6 +35058,12 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h + + + + + + @@ -35165,7 +35288,7 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h - vaccine-induced host response + vaccine-induced response vaccine-induced T cell activation @@ -35236,7 +35359,6 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h - @@ -35565,7 +35687,6 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h - @@ -35811,7 +35932,7 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h - vaccine-induced host response + vaccine-induced response vaccine-induced T cell proliferation @@ -35822,7 +35943,7 @@ https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.h Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced adaptive immune response @@ -36256,7 +36377,7 @@ MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replac - vaccine-induced host response + vaccine-induced response vaccine-induced gene up-regulation controlling intracellular bacterial replication @@ -36452,7 +36573,7 @@ MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replac - vaccine-induced host response + vaccine-induced response vaccine-induced T cell differentiation @@ -36553,7 +36674,7 @@ MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replac Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced cell activation @@ -36576,9 +36697,9 @@ MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replac - + Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced antibacterial agglutination antibody response @@ -37414,7 +37535,7 @@ MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replac Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced down-regulated gene expression @@ -37539,9 +37660,9 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito - + Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced antiviral neutralizing antibody response @@ -37717,7 +37838,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced follicular dendritic cell activation @@ -37876,7 +37997,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito - vaccine-induced host response + vaccine-induced response vaccine-induced T cell interferon-gamma production @@ -38083,8 +38204,9 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito Oliver He - vaccine-induced host response - vaccine-induced host gene response + vaccine-induced host gene response + vaccine-induced response + vaccine-induced gene response @@ -38093,12 +38215,13 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito - Any immune system process that functions in the calibrated response of the host to a vaccine. + Any immune system process that functions in the calibrated response of the organism to a vaccine. The definition of this term is based on the definition of 'immune response (GO:0006955)' . It is a child term of this GO term. Asiyah Yu Lin Oliver He - vaccine-induced host response - vaccine-induced host immune response + vaccine-induced host immune response + vaccine-induced response + vaccine-induced immune response @@ -38106,33 +38229,27 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito - + - - + + - - - - - - - - - - - - + + - a processual entity that specifies host response to a vaccine. + Process that specifies the organism's response to an administered vaccine. + Asiyah Yu Lin + Jie Zheng Oliver He + vaccine-induced host response + https://github.com/vaccineontology/VO/issues/781 process - vaccine-induced host response + vaccine-induced response @@ -38153,7 +38270,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito - a processual entity that specifies host response to a vaccine component. + Process that specifies host response to a vaccine component. Oliver He process host response to vaccine component @@ -38488,11 +38605,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito - + Oliver He - immunoglobulin mediated immune response to vaccine - vaccine-induced host response - vaccine-induced antibody mediated immune response + + + obsolete vaccine-induced antibody mediated immune response + true @@ -38732,6 +38850,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -38781,6 +38905,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + Oliver He recombinant B. abortus L7/L12 vaccine PMID:8873388 @@ -38812,6 +38942,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -39416,7 +39552,14 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + + @@ -39488,7 +39631,14 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + + @@ -39541,7 +39691,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced leukocyte activation @@ -39760,7 +39910,14 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + + @@ -39779,6 +39936,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -39915,7 +40078,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito a vaccine-induced T cell interferon-gramm production that results from the addition of a vaccine adjuvant Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced, adjuvant boosted T cell interferon-gramm production @@ -39938,6 +40101,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -39957,6 +40126,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -39976,7 +40151,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito Oliver He - vaccine-induced host response + vaccine-induced response mucosal immune response to vaccine @@ -40224,7 +40399,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito A vaccine-induced adjuvant boosted T cell interferon-gramm production that results from the addition of a IL-15 vaccine adjuvant Oliver He PMID: 18472194 - vaccine-induced host response + vaccine-induced response vaccine-induced T cell interferon-gramm production boosted by IL-15 vaccine adjuvant @@ -40246,7 +40421,14 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + + A prime-boost vaccine that contains one DNA vaccine for priming and at least one other vaccine for boosting. Oliver He Rebecca Racz @@ -40339,6 +40521,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -40358,7 +40546,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito Oliver He - vaccine-induced host response + vaccine-induced response organ or tissue specific immune response to vaccine @@ -40489,7 +40677,14 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + + @@ -40514,6 +40709,7 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + @@ -40521,6 +40717,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -40715,6 +40917,13 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + + a Varicella-zoster virus vaccine that is live attenuated. Oliver He vaccine @@ -40880,7 +41089,14 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + + Oliver He WEB: http://www.ncbi.nlm.nih.gov/pubmed/10700309 vaccine @@ -41084,6 +41300,12 @@ Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Edito + + + + + + @@ -41488,6 +41710,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -41855,7 +42083,14 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -41882,6 +42117,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -41912,6 +42153,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + A subunit vaccine that is made using a part of whole organism as subunit for vaccine development. Oliver He vaccine @@ -41965,6 +42212,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -41995,7 +42248,14 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -42026,6 +42286,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -42065,7 +42331,7 @@ VE = (p-c)/p(1-c) x 100%. - A process that results in an adaptive immune response to one or more antigens. + Process that results in an adaptive immune response to one or more antigens. Allen Xiang Anna Maria Masci Barry Smith @@ -42138,7 +42404,7 @@ VE = (p-c)/p(1-c) x 100%. - + @@ -42198,7 +42464,7 @@ VE = (p-c)/p(1-c) x 100%. - disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease. + Process that prevents a disorder that is the physical basis of a disease. Allen Xiang Oliver He process @@ -42211,7 +42477,7 @@ VE = (p-c)/p(1-c) x 100%. - disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease. + Process that leads to treat a disorder that is the physical basis of a disease. Allen Xiang Oliver He process @@ -42262,6 +42528,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -42280,7 +42552,6 @@ VE = (p-c)/p(1-c) x 100%. - @@ -42350,6 +42621,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -42410,7 +42687,14 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + a diphtheria vaccine that uses diphtheria toxoid Oliver He vaccine @@ -42579,6 +42863,13 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -42623,6 +42914,13 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -42706,6 +43004,13 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -42791,12 +43096,19 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -42840,6 +43152,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -42883,6 +43201,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -42902,6 +43226,12 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + @@ -42919,6 +43249,13 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -43060,6 +43397,13 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -43127,6 +43471,13 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -43145,12 +43496,19 @@ VE = (p-c)/p(1-c) x 100%. + + + + + + + @@ -43256,6 +43614,12 @@ Toxins can be small molecules, peptides, or proteins that are capable of causing + + + + + + @@ -43361,7 +43725,14 @@ Toxins can be small molecules, peptides, or proteins that are capable of causing + + + + + + + @@ -43400,7 +43771,7 @@ Toxins can be small molecules, peptides, or proteins that are capable of causing Oliver He - vaccine-induced host response + vaccine-induced response vaccine-induced up-regulated gene expression @@ -43900,7 +44271,7 @@ Toxins can be small molecules, peptides, or proteins that are capable of causing Oliver He - vaccine-induced host response + vaccine-induced response vaccine specific T cell cytokine production @@ -43911,7 +44282,7 @@ Toxins can be small molecules, peptides, or proteins that are capable of causing Oliver He - vaccine-induced host response + vaccine-induced response vaccine specific T cell mediated cytotoxicity @@ -43946,7 +44317,7 @@ Toxins can be small molecules, peptides, or proteins that are capable of causing - A processual entity by which a vaccine is tested clinically for safety and effectiveness. Clinical trials are conducted in phases. Classically, clinical trials unfold in three phases in order to gather data and information about a vaccine and its performance. This will form the basis of a dossier submitted to regulatory authorities by way of an application for licensure. After a vaccine is licensed and is being used by large numbers of people, a Phase IV study may or may not be taken for vaccine clinical evaluation. + Planned process by which a vaccine is tested clinically for safety and effectiveness. Clinical trials are conducted in phases. Classically, clinical trials unfold in three phases in order to gather data and information about a vaccine and its performance. This will form the basis of a dossier submitted to regulatory authorities by way of an application for licensure. After a vaccine is licensed and is being used by large numbers of people, a Phase IV study may or may not be taken for vaccine clinical evaluation. Most vaccines against a pathogen (e.g., HIV) are not tested by vaccinating people and then deliberately exposing them to virulent pathogen (e.g., HIV). This strategy is never for a vaccine against a disease as serious as HIV. The best way to determine if a vaccine is effective is to test it in a randomized, controlled, double-blind clinical trial. This type of trial is often referred to as the gold standard in medical research and provides the strongest evidence for the efficacy of a vaccine. Oliver He @@ -44298,6 +44669,13 @@ The best way to determine if a vaccine is effective is to test it in a randomize + + + + + + + vaccine E. coli live attenuated vaccine @@ -44462,6 +44840,13 @@ The best way to determine if a vaccine is effective is to test it in a randomize + + + + + + + An E. coli vaccine that uses subunit antigen type. vaccine E. coli subunit vaccine @@ -44473,12 +44858,19 @@ The best way to determine if a vaccine is effective is to test it in a randomize + + + + + + + @@ -44522,10 +44914,11 @@ The best way to determine if a vaccine is effective is to test it in a randomize - + Vaccine induced immue response mediated hrough a body fluid Asiyah Yu Lin - vaccine-induced host response + vaccine-induced antibody mediated immune response + vaccine-induced response vaccine-induced humoral immune response @@ -45701,7 +46094,14 @@ However, even this may not be comprehensive. + + + + + + + @@ -45737,7 +46137,14 @@ However, even this may not be comprehensive. + + + + + + + @@ -45986,7 +46393,7 @@ However, even this may not be comprehensive. - A processual entity that regulates vaccine-related processes, such as vaccine trial, vaccine license application. + Process that regulates vaccine-related processes, such as vaccine trial, vaccine license application. Oliver He process vaccine regulation @@ -45998,7 +46405,7 @@ However, even this may not be comprehensive. - A processual entity of transporting vaccine from one place to another place. + Process of transporting vaccine from one place to another place. Oliver He process vaccine transportation @@ -46842,6 +47249,12 @@ However, even this may not be comprehensive. + + + + + + @@ -47038,7 +47451,14 @@ However, even this may not be comprehensive. + + + + + + + @@ -48012,7 +48432,14 @@ However, even this may not be comprehensive. + + + + + + + @@ -48037,7 +48464,14 @@ However, even this may not be comprehensive. + + + + + + + @@ -48101,7 +48535,14 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + + @@ -48484,7 +48925,14 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + + @@ -48504,6 +48952,13 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + + @@ -48620,7 +49075,14 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + + @@ -48788,6 +49250,7 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + @@ -48795,6 +49258,12 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + @@ -48850,6 +49319,7 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + @@ -48857,6 +49327,12 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + @@ -48900,6 +49376,7 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + @@ -48907,6 +49384,12 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + @@ -48993,7 +49476,14 @@ a vaccine-associated gene that exists in a pathogen and has been engineered for + + + + + + + @@ -49336,17 +49826,28 @@ Ref: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73. - + - - + + + + + + + + + + + + - Immune correlate of protection is a host immune response to vaccine that correlates with protective induced by the vaccine. + Process profile that is measurable and the measured data indicates the degree of immunological protection in the vaccine recipient. More specifically, it is the process in some immune response component (such as gene, protein, etc.) which serves as an immune biomarker. Oliver He - vaccine-induced host response - vaccine-induced immune correlate of protection + correlate of immune protection + process profile + correlated profile of immune protection @@ -49355,10 +49856,11 @@ Ref: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73. - Serological correlate of protection is an immune correlate of protection that is reflected by serologic antibody levels. + A correlated profile of immune protection that is reflected by serologic antibody levels. Oliver He - vaccine-induced host response - serologic correlate of protection + serologic correlate of protection + process profile + serologic correlated profile of immune protection @@ -49367,10 +49869,11 @@ Ref: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73. - A cell mediated immune correlate of protection is an immune correlate of protection that is reflected by a cell mediated immune response. + A correlated profile of immune protection that is reflected by a cell mediated immune response. Oliver He - vaccine-induced host response - cell mediated immune correlate of protection + cell mediated immune correlate of protection + process profile + cell mediated correlated profile of immune protection @@ -51248,7 +51751,14 @@ marker vaccine + + + + + + + An E. coli vaccine that uses a live mutant by knocking out one gene(s) from a wild type E. coli. Oliver He vaccine @@ -51261,6 +51771,13 @@ marker vaccine + + + + + + + an E. coli vaccine that uses toxoid antigen Oliver He vaccine @@ -51286,6 +51803,13 @@ marker vaccine + + + + + + + An E. coli vaccine that uses a recombinant vaccine vector to express an E. coli antigen(s) vaccine recombinant vaccine vector E. coli vaccine @@ -51384,6 +51908,13 @@ marker vaccine + + + + + + + vaccine inactivated E. coli vaccine @@ -51786,6 +52317,7 @@ marker vaccine + @@ -51793,6 +52325,12 @@ marker vaccine + + + + + + @@ -52703,25 +53241,10 @@ marker vaccine - - - - - - - - - - - - - - - - - - vaccine-induced host response - vaccine-induced mouse immune response + + + obsolete vaccine-induced mouse immune response + true @@ -53475,6 +53998,12 @@ marker vaccine + + + + + + a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is a natural host for the vector. Oliver He WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf @@ -53506,6 +54035,12 @@ marker vaccine + + + + + + a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is not one of the natural hosts for the vector. Oliver He WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf @@ -53884,7 +54419,7 @@ marker vaccine - inactivation is a processual entity that produces inactive material. + Inactivation is a processual entity that produces inactive material. Allen Xiang Melanie Courtot Oliver He @@ -54122,7 +54657,7 @@ marker vaccine - survival of live vaccine inside host is a processual entity that represents the survival of a live vaccine inside its host. The time of the survival is often important for the success of the live vaccine. + Survival of live vaccine inside host is a process that represents the survival of a live vaccine inside its host. The time of the survival is often important for the success of the live vaccine. Oliver He process survival of live vaccine inside host @@ -54134,7 +54669,7 @@ marker vaccine - persistence of vaccine induced immune response is a processual entity that indicates the persistence of an immune reponse induced by a vaccine in a vaccinated host. + Persistence of vaccine induced immune response is a processual entity that indicates the persistence of an immune reponse induced by a vaccine in a vaccinated host. Oliver He process persistence of vaccine induced immune response @@ -54612,8 +55147,15 @@ marker vaccine + + + + + + + @@ -54692,6 +55234,12 @@ marker vaccine + + + + + + Oliver He pCIBLSOmp31 vaccine @@ -55926,6 +56474,12 @@ marker vaccine + + + + + + a subunit vaccien that uses LPS as protective antigen Oliver He vaccine @@ -57094,6 +57648,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + Oliver He vaccine capsular polysaccharide subunit vaccine @@ -57116,6 +57676,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + a subunit vaccine that uses polysaccharide as protective antigen Oliver He vaccine @@ -58091,6 +58657,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + Brucella BFR antigen vaccine recombinant Brucella abortus Bfr protein vaccine vaccine @@ -58104,6 +58676,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + Brucella abortus Omp16 vaccine vaccine Brucella abortus subunit vaccine using Omp16 @@ -58116,6 +58694,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + vaccine B. melitensis DNA vaccine encoding Bp26 and Tf @@ -58725,6 +59309,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + an inactivation vaccine that is prepared by irradiation inactivation. Asiyah Yu Lin Oliver He @@ -59051,7 +59641,14 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi CRP-10 protein. Oliver He vaccine @@ -59064,7 +59661,14 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G2 protein. Oliver He vaccine @@ -59077,7 +59681,14 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G4 protein. Oliver He vaccine @@ -59090,7 +59701,14 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + @@ -59109,7 +59727,14 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi TSA-1 protein. Oliver He vaccine @@ -59170,7 +59795,14 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + @@ -59220,7 +59852,27 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + + + + + + + + + + + + + + a cocktail vaccine that contains both subunit vaccine and inactivated whole organism vaccines. Oliver He vaccine @@ -59233,6 +59885,19 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + + + + + + + + a prime-boost vaccine with DNA vaccine priming that contains a subunit vaccine for boosting Oliver He vaccine @@ -59245,6 +59910,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + a prime-boost vaccine with a DNA vaccine priming that contains a Ad vector vaccine for boosting Oliver He vaccine @@ -59257,6 +59928,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + a conjugate vaccine that conjugate more than one open reading frames of protective antigens or conjugate a protective antigen to a carrier protein. An example of fusion protein vaccine is Mtb72f fusion protein vaccine. Reference: PubMed: 15187142. Oliver He @@ -62888,6 +63565,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -62915,6 +63598,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -62936,6 +63625,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -62963,6 +63658,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -63819,6 +64520,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -63851,6 +64558,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -63883,6 +64596,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -66008,13 +66727,13 @@ However, running the reasoner takes time. As a way to reducing the time, I have - + - + @@ -66044,6 +66763,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -66071,6 +66796,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -66098,6 +66829,12 @@ However, running the reasoner takes time. As a way to reducing the time, I have + + + + + + @@ -66125,6 +66862,12 @@ However, running the reasoner takes time. 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As a way to reducing the time, I have + + + + + + + @@ -93828,6 +95353,12 @@ Recommendations for the production and control of influenza vaccine (inactivated + + + + + + @@ -100437,6 +101968,12 @@ Recommendations for the production and control of influenza vaccine (inactivated + + + + + + Oliver He Rebecca Racz vaccine @@ -103443,11 +104980,11 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - a vaccine-induced host gene response that represents a vaccine adverse event response associated with a host susceptibility gene. + a vaccine-induced gene response that represents a vaccine adverse event response associated with a host susceptibility gene. Oliver He - host susceptibility gene response to VAE - vaccine-induced host response - host susceptibility gene response to vaccine adverse event + host susceptibility gene response to vaccine adverse event + vaccine-induced response + susceptibility gene response to vaccine adverse event @@ -103456,8 +104993,9 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - vaccine-induced host response - host immune factor-induced control of intracellular replication of live attenuated vaccine + host immune factor-induced control of intracellular replication of live attenuated vaccine + vaccine-induced response + immune factor-induced control of intracellular replication of live attenuated vaccine @@ -103690,15 +105228,10 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - - - - - - - - vaccine-induced host response - RB51 induced protection against B.suis + + + obsolete RB51 induced protection against B.suis + true @@ -103777,7 +105310,7 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ when the vaccination of a significant portion of a population (or herd), in contagious diseases that are transmitted from individual to individual, chains of infection are likely to be disrupted, so the large numbers of a population are immue or less susceptible to the disease. Asiyah Yu Lin http://en.wikipedia.org/wiki/Herd_immunity - vaccine-induced host response + vaccine-induced response vaccine-induced herd immunity @@ -103931,12 +105464,13 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - + an vaccine-induced host response that shows augmented protection and cellular immunity after a host protein is used as adjuvant. Oliver He Rebecca Racz - vaccine-induced host response - augmented protection and cellular immunity using host protein as adjuvant + + obsolete augmented protection and cellular immunity using host protein as adjuvant + true @@ -104068,15 +105602,10 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - - - - - - - - vaccine-induced host response - RB51 induced protection against B.abortus + + + obsolete RB51 induced protection against B.abortus + true @@ -104084,15 +105613,10 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - - - - - - - - vaccine-induced host response - RB51 induced protection against B.canis + + + obsolete RB51 induced protection against B.canis + true @@ -104100,15 +105624,10 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - - - - - - - - vaccine-induced host response - RB51 induced protection against B.Melitensis + + + obsolete RB51 induced protection against B.Melitensis + true @@ -104318,15 +105837,10 @@ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ - - - - - - - - vaccine-induced host response - RB51 induced host immune response + + + obsolete RB51 induced host immune response + true @@ -104948,15 +106462,10 @@ And the following precancerous or dysplastic lesions caused by HPV types 6, 11, - - - - - - - - vaccine-induced host response - RB51 induced protection against B. ovis + + + obsolete RB51 induced protection against B. ovis + true @@ -105321,6 +106830,12 @@ And the following precancerous or dysplastic lesions caused by HPV types 6, 11, + + + + + + @@ -105428,9 +106943,10 @@ And the following precancerous or dysplastic lesions caused by HPV types 6, 11, - - vaccine-induced host response - RB51 induced immune protection + + + obsolete RB51 induced immune protection + true @@ -105438,9 +106954,10 @@ And the following precancerous or dysplastic lesions caused by HPV types 6, 11, - - vaccine-induced host response - RB51 induced immune response without protection + + + obsolete RB51 induced immune response without protection + true @@ -106969,6 +108486,7 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + @@ -106976,6 +108494,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -108324,6 +109848,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + A Meningicoccal Conjugate and Haemophilis B Vaccine manufactured outside of the U.S. Kallan Roan Oliver He @@ -108405,7 +109935,14 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + @@ -108473,6 +110010,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -108496,13 +110039,26 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + + + + + + + @@ -108522,6 +110078,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + vaccine Bordetella pertussis filamentous hemagglutinin vaccine, inactivated @@ -108532,6 +110094,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -108557,6 +110125,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -108582,6 +110156,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -108610,6 +110190,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -108634,12 +110220,24 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + + + + + + @@ -108662,12 +110260,24 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + + + + + + @@ -108687,12 +110297,24 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + + + + + + @@ -108712,12 +110334,24 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + + + + + + @@ -108737,12 +110371,24 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + + + + + + + @@ -108762,6 +110408,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -108818,6 +110470,7 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + @@ -108827,6 +110480,12 @@ Aluminum hydroxide. 0.35 mg (as aluminum) + + + + + + @@ -110796,6 +112455,12 @@ over. + + + + + + @@ -110831,6 +112496,12 @@ over. + + + + + + @@ -110857,6 +112528,12 @@ over. + + + + + + @@ -110889,6 +112566,12 @@ over. + + + + + + @@ -110915,6 +112598,12 @@ over. + + + + + + @@ -110949,6 +112638,12 @@ over. + + + + + + @@ -110978,6 +112673,12 @@ over. + + + + + + @@ -111001,6 +112702,12 @@ over. + + + + + + @@ -111041,6 +112748,12 @@ over. + + + + + + @@ -111073,6 +112786,12 @@ over. + + + + + + @@ -111105,6 +112824,12 @@ over. + + + + + + @@ -111153,7 +112878,14 @@ over. + + + + + + + vaccine Streptococcus pneumoniae capsular antigen diphtheria CRM197 protein conjugate vaccine @@ -111170,6 +112902,12 @@ over. + + + + + + @@ -111198,6 +112936,12 @@ over. + + + + + + @@ -111226,6 +112970,12 @@ over. + + + + + + @@ -111254,6 +113004,12 @@ over. + + + + + + @@ -111282,6 +113038,12 @@ over. + + + + + + @@ -111310,6 +113072,12 @@ over. + + + + + + @@ -111338,6 +113106,12 @@ over. + + + + + + @@ -111366,6 +113140,12 @@ over. + + + + + + @@ -111394,6 +113174,12 @@ over. + + + + + + @@ -111422,6 +113208,12 @@ over. + + + + + + @@ -111450,6 +113242,12 @@ over. + + + + + + @@ -111478,6 +113276,12 @@ over. + + + + + + @@ -111506,6 +113310,12 @@ over. + + + + + + @@ -112545,6 +114355,12 @@ over. + + + + + + @@ -112575,6 +114391,12 @@ over. + + + + + + @@ -112605,6 +114427,12 @@ over. + + + + + + @@ -112630,7 +114458,7 @@ over. a vaccine-induced down-regulation gene expression that occurs in live attenuated vaccine and compared with the host system infected with live wild type virulent strain which is the parent strain of this live attenuated vaccine. Oliver He Rebecca Racz - vaccine-induced host response + vaccine-induced response live attenuated vaccine-induced down-regulated gene expression compared to infection with wild type pathogen @@ -112648,6 +114476,12 @@ over. + + + + + + @@ -112678,6 +114512,12 @@ over. + + + + + + @@ -112708,6 +114548,12 @@ over. + + + + + + @@ -112738,6 +114584,12 @@ over. + + + + + + @@ -112768,6 +114620,12 @@ over. + + + + + + @@ -112798,6 +114656,12 @@ over. + + + + + + @@ -112828,6 +114692,12 @@ over. + + + + + + @@ -112858,6 +114728,12 @@ over. + + + + + + @@ -112888,6 +114764,12 @@ over. + + + + + + @@ -112918,6 +114800,12 @@ over. + + + + + + @@ -112972,7 +114860,7 @@ over. A vaccine-induced up-regulation gene expression that occurs in live attenuated vaccine and compared with the host system infected with live wild type virulent strain which is the parent strain of this live attenuated vaccine. Oliver He Rebecca Racz - vaccine-induced host response + vaccine-induced response live attenuated vaccine-induced up-regulated gene expression compared to infection with wild type pathogen @@ -113076,6 +114964,12 @@ over. + + + + + + @@ -113187,6 +115081,12 @@ over. + + + + + + @@ -113227,6 +115127,12 @@ over. + + + + + + @@ -113608,6 +115514,7 @@ over. + @@ -113615,6 +115522,12 @@ over. + + + + + + @@ -113640,6 +115553,12 @@ over. + + + + + + @@ -113767,6 +115686,12 @@ over. + + + + + + @@ -114070,12 +115995,24 @@ over. + + + + + + + + + + + + @@ -114098,14 +116035,27 @@ over. + + + + + + + + + + + + + @@ -114128,12 +116078,24 @@ over. + + + + + + + + + + + + @@ -114156,6 +116118,12 @@ over. + + + + + + @@ -114181,6 +116149,12 @@ over. + + + + + + @@ -114209,6 +116183,12 @@ over. + + + + + + @@ -114246,6 +116226,12 @@ over. + + + + + + @@ -114274,6 +116260,12 @@ over. + + + + + + @@ -114365,12 +116357,24 @@ over. + + + + + + + + + + + + @@ -114392,7 +116396,14 @@ over. + + + + + + + A clostridium tetani vaccine that consists of formaldehyde inactivated tetanospasmin (aka tetanus toxoid). Hector Guzman-Orozco Oliver He @@ -114407,12 +116418,24 @@ over. + + + + + + + + + + + + @@ -114441,12 +116464,24 @@ over. + + + + + + + + + + + + @@ -114475,14 +116510,27 @@ over. + + + + + + + + + + + + + @@ -114508,12 +116556,24 @@ over. + + + + + + + + + + + + @@ -114536,12 +116596,24 @@ over. + + + + + + + + + + + + @@ -114564,12 +116636,24 @@ over. + + + + + + + + + + + + @@ -114599,12 +116683,24 @@ over. + + + + + + + + + + + + @@ -114634,12 +116730,24 @@ over. + + + + + + + + + + + + @@ -114668,12 +116776,24 @@ over. + + + + + + + + + + + + @@ -114702,12 +116822,24 @@ over. + + + + + + + + + + + + @@ -114730,12 +116862,24 @@ over. + + + + + + + + + + + + @@ -114757,6 +116901,7 @@ over. + @@ -114765,6 +116910,12 @@ over. + + + + + + @@ -114794,6 +116945,12 @@ over. + + + + + + @@ -114828,6 +116985,12 @@ over. + + + + + + @@ -114859,6 +117022,12 @@ over. + + + + + + @@ -114896,6 +117065,12 @@ over. + + + + + + @@ -114932,6 +117107,12 @@ over. + + + + + + @@ -114960,6 +117141,12 @@ over. + + + + + + @@ -115441,6 +117628,12 @@ over. + + + + + + @@ -115475,12 +117668,24 @@ over. + + + + + + + + + + + + @@ -115503,6 +117708,12 @@ over. + + + + + + @@ -115534,6 +117745,12 @@ over. + + + + + + @@ -115562,6 +117779,12 @@ over. + + + + + + @@ -115596,7 +117819,14 @@ over. + + + + + + + @@ -115625,6 +117855,12 @@ over. + + + + + + @@ -115653,6 +117889,12 @@ over. + + + + + + @@ -115687,6 +117929,12 @@ over. + + + + + + @@ -115721,6 +117969,12 @@ over. + + + + + + @@ -115755,6 +118009,12 @@ over. + + + + + + @@ -115911,6 +118171,12 @@ over. + + + + + + @@ -115947,6 +118213,12 @@ over. + + + + + + @@ -115976,6 +118248,12 @@ over. + + + + + + @@ -116011,6 +118289,12 @@ over. + + + + + + @@ -116043,6 +118327,12 @@ over. + + + + + + @@ -116222,12 +118512,24 @@ over. + + + + + + + + + + + + @@ -116251,13 +118553,26 @@ over. + + + + + + + + + + + + + @@ -116280,12 +118595,24 @@ over. + + + + + + + + + + + + @@ -116308,12 +118635,24 @@ over. + + + + + + + + + + + + @@ -116336,6 +118675,12 @@ over. + + + + + + @@ -116377,6 +118722,12 @@ over. + + + + + + @@ -116408,6 +118759,12 @@ over. + + + + + + @@ -116449,6 +118806,12 @@ over. + + + + + + @@ -116578,7 +118941,14 @@ over. + + + + + + + @@ -116657,6 +119027,12 @@ over. + + + + + + @@ -116694,6 +119070,12 @@ over. + + + + + + @@ -116725,6 +119107,12 @@ over. + + + + + + @@ -118538,6 +120926,13 @@ over. + + + + + + + @@ -118570,6 +120965,12 @@ over. + + + + + + @@ -118604,6 +121005,12 @@ over. + + + + + + @@ -118675,12 +121082,19 @@ over. + + + + + + + @@ -118709,12 +121123,19 @@ over. + + + + + + + @@ -118751,6 +121172,12 @@ over. + + + + + + @@ -118785,6 +121212,12 @@ over. + + + + + + @@ -118819,6 +121252,12 @@ over. + + + + + + @@ -118853,6 +121292,12 @@ over. + + + + + + @@ -118887,6 +121332,12 @@ over. + + + + + + @@ -120505,6 +122956,12 @@ over. + + + + + + @@ -120554,6 +123011,12 @@ over. + + + + + + @@ -120671,6 +123134,7 @@ over. + @@ -120696,12 +123160,24 @@ over. + + + + + + + + + + + + @@ -122366,6 +124842,12 @@ over. + + + + + + @@ -122567,6 +125049,7 @@ over. + @@ -122592,12 +125075,24 @@ over. + + + + + + + + + + + + @@ -122708,6 +125203,12 @@ over. + + + + + + @@ -126276,6 +128777,12 @@ over. + + + + + + @@ -134067,6 +136574,12 @@ over. + + + + + + @@ -134110,6 +136623,12 @@ over. + + + + + + @@ -135522,7 +138041,6 @@ over. - @@ -135913,7 +138431,14 @@ over. + + + + + + + @@ -135941,6 +138466,12 @@ over. + + + + + + @@ -135973,6 +138504,12 @@ over. + + + + + + @@ -136005,6 +138542,12 @@ over. + + + + + + @@ -136116,12 +138659,24 @@ over. + + + + + + + + + + + + @@ -136198,6 +138753,12 @@ over. + + + + + + @@ -136240,6 +138801,12 @@ over. + + + + + + @@ -136271,6 +138838,12 @@ over. + + + + + + @@ -136302,6 +138875,12 @@ over. + + + + + + @@ -136333,12 +138912,30 @@ over. + + + + + + + + + + + + + + + + + + @@ -136417,6 +139014,12 @@ over. + + + + + + @@ -136460,6 +139063,12 @@ over. + + + + + + @@ -136827,7 +139436,14 @@ over. + + + + + + + @@ -136859,6 +139475,12 @@ over. + + + + + + @@ -136930,6 +139552,12 @@ over. + + + + + + @@ -137229,12 +139857,30 @@ over. + + + + + + + + + + + + + + + + + + @@ -137273,6 +139919,12 @@ over. + + + + + + @@ -137320,12 +139972,30 @@ over. + + + + + + + + + + + + + + + + + + @@ -137434,6 +140104,7 @@ over. + @@ -137452,6 +140123,12 @@ over. + + + + + + @@ -137663,6 +140340,7 @@ over. + @@ -137687,6 +140365,12 @@ over. + + + + + + @@ -137899,6 +140583,7 @@ over. + @@ -137923,6 +140608,12 @@ over. + + + + + + @@ -138147,6 +140838,7 @@ over. + @@ -138171,6 +140863,12 @@ over. + + + + + + @@ -141644,7 +144342,14 @@ over. + + + + + + + @@ -141676,6 +144381,12 @@ over. + + + + + + @@ -141704,6 +144415,12 @@ over. + + + + + + @@ -141779,6 +144496,12 @@ over. + + + + + + @@ -141815,6 +144538,12 @@ over. + + + + + + @@ -141862,6 +144591,12 @@ over. + + + + + + @@ -142382,12 +145117,30 @@ over. + + + + + + + + + + + + + + + + + + @@ -142490,12 +145243,30 @@ over. + + + + + + + + + + + + + + + + + + @@ -142573,6 +145344,12 @@ over. + + + + + + @@ -142691,12 +145468,24 @@ over. + + + + + + + + + + + + @@ -142776,12 +145565,24 @@ over. + + + + + + + + + + + + @@ -142862,6 +145663,12 @@ over. + + + + + + @@ -143067,12 +145874,24 @@ over. + + + + + + + + + + + + @@ -143108,6 +145927,12 @@ over. + + + + + + @@ -143227,12 +146052,24 @@ over. + + + + + + + + + + + + @@ -143313,6 +146150,12 @@ over. + + + + + + @@ -143405,6 +146248,12 @@ over. + + + + + + @@ -143481,12 +146330,24 @@ over. + + + + + + + + + + + + Kallan Roan Oliver He http://purl.bioontology.org/ontology/RXNORM/1300383 @@ -143556,6 +146417,12 @@ over. + + + + + + @@ -143650,6 +146517,12 @@ over. + + + + + + @@ -143765,12 +146638,24 @@ over. + + + + + + + + + + + + @@ -143832,12 +146717,24 @@ over. + + + + + + + + + + + + @@ -143919,6 +146816,12 @@ over. + + + + + + @@ -144041,6 +146944,7 @@ over. + @@ -144058,6 +146962,12 @@ over. + + + + + + @@ -144814,6 +147724,7 @@ over. + @@ -144821,6 +147732,12 @@ over. + + + + + + @@ -144918,6 +147835,7 @@ over. + @@ -144925,6 +147843,12 @@ over. + + + + + + Ningxian Fan Oliver He Ronak Sutariya @@ -144938,6 +147862,7 @@ over. + @@ -144945,6 +147870,12 @@ over. + + + + + + @@ -145016,6 +147947,7 @@ over. + @@ -145023,6 +147955,12 @@ over. + + + + + + @@ -145042,6 +147980,7 @@ over. + @@ -145049,6 +147988,12 @@ over. + + + + + + @@ -145068,6 +148013,7 @@ over. + @@ -145075,6 +148021,12 @@ over. + + + + + + @@ -145198,6 +148150,7 @@ over. + @@ -145205,6 +148158,12 @@ over. + + + + + + @@ -145510,6 +148469,7 @@ over. + @@ -145517,6 +148477,12 @@ over. + + + + + + Ningxian Fan Oliver He Ronak Sutariya @@ -145838,7 +148804,14 @@ over. + + + + + + + @@ -146318,7 +149291,14 @@ over. + + + + + + + @@ -146398,7 +149378,14 @@ over. + + + + + + + @@ -146438,7 +149425,14 @@ over. + + + + + + + @@ -146458,7 +149452,14 @@ over. + + + + + + + @@ -146498,7 +149499,14 @@ over. + + + + + + + @@ -146569,7 +149577,21 @@ over. + + + + + + + + + + + + + + @@ -146630,7 +149652,14 @@ over. + + + + + + + @@ -146666,7 +149695,14 @@ over. + + + + + + + @@ -146686,7 +149722,14 @@ over. + + + + + + + @@ -146746,7 +149789,14 @@ over. + + + + + + + @@ -146786,7 +149836,14 @@ over. + + + + + + + @@ -146860,7 +149917,14 @@ over. + + + + + + + Ningxian Fan Oliver He Ronak Sutariya @@ -146894,7 +149958,14 @@ over. + + + + + + + @@ -146914,7 +149985,14 @@ over. + + + + + + + @@ -146954,7 +150032,14 @@ over. + + + + + + + @@ -146994,7 +150079,14 @@ over. + + + + + + + @@ -147275,6 +150367,13 @@ over. + + + + + + + @@ -147295,6 +150394,13 @@ over. + + + + + + + @@ -147314,7 +150420,14 @@ over. + + + + + + + @@ -147334,7 +150447,13 @@ over. - + + + + + + + @@ -147354,7 +150473,14 @@ over. + + + + + + + @@ -147374,8 +150500,15 @@ over. + + + + + + + @@ -147396,7 +150529,14 @@ over. + + + + + + + @@ -147456,7 +150596,14 @@ over. + + + + + + + @@ -147476,7 +150623,14 @@ over. + + + + + + + @@ -147496,7 +150650,14 @@ over. + + + + + + + @@ -147516,7 +150677,14 @@ over. + + + + + + + @@ -147556,7 +150724,14 @@ over. + + + + + + + @@ -147636,7 +150811,14 @@ over. + + + + + + + @@ -147656,7 +150838,21 @@ over. + + + + + + + + + + + + + + @@ -147716,7 +150912,14 @@ over. + + + + + + + @@ -147763,7 +150966,14 @@ over. + + + + + + + @@ -147783,7 +150993,14 @@ over. + + + + + + + @@ -147803,7 +151020,14 @@ over. + + + + + + + @@ -147823,7 +151047,14 @@ over. + + + + + + + @@ -147843,7 +151074,14 @@ over. + + + + + + + @@ -148010,7 +151248,14 @@ over. + + + + + + + @@ -148110,7 +151355,14 @@ over. + + + + + + + @@ -148190,7 +151442,14 @@ over. + + + + + + + @@ -148250,7 +151509,14 @@ over. + + + + + + + @@ -148330,7 +151596,14 @@ over. + + + + + + + @@ -148449,7 +151722,14 @@ over. + + + + + + + @@ -148559,6 +151839,12 @@ over. + + + + + + @@ -148604,6 +151890,12 @@ over. + + + + + + @@ -148648,7 +151940,14 @@ over. + + + + + + + @@ -148674,7 +151973,14 @@ over. + + + + + + + @@ -148700,7 +152006,14 @@ over. + + + + + + + @@ -148727,7 +152040,15 @@ over. + + + + + + + + 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+169287,12 @@ over. + + + + + + @@ -163953,6 +169374,12 @@ over. + + + + + + @@ -163981,6 +169408,12 @@ over. + + + + + + @@ -164378,6 +169811,7 @@ over. + @@ -164396,12 +169830,30 @@ over. + + + + + + + + + + + + + + + + + + @@ -164440,6 +169892,12 @@ over. + + + + + + @@ -164485,12 +169943,30 @@ over. + + + + + + + + + + + + + + + + + + @@ -164578,6 +170054,12 @@ over. + + + + + + @@ -164615,6 +170097,12 @@ over. + + + + + + @@ -164649,6 +170137,12 @@ over. + + + + + + @@ -164689,6 +170183,12 @@ over. + + + + + + @@ -164724,6 +170224,12 @@ over. + + + + + + @@ -164753,6 +170259,12 @@ over. + + + + + + @@ -164790,6 +170302,12 @@ over. + + + + + + @@ -164824,6 +170342,12 @@ over. + + + + + + @@ -164864,6 +170388,12 @@ over. + + + + + + @@ -164899,6 +170429,12 @@ over. + + + + + + @@ -165550,6 +171086,12 @@ over. + + + + + + @@ -165775,7 +171317,7 @@ over. vaccine-induced T-helper 1 type immune response that is indicated by the presence of Interferon-gamma production Anthony Huffman Oliver He - vaccine-induced host response + vaccine-induced response vaccine specific interferon-γ immune response @@ -165788,7 +171330,7 @@ over. vaccine-induced T-helper 1 type immune response that is indicated by the presence of interleukin-2 production Anthony Huffman Oliver He - vaccine-induced host response + vaccine-induced response vaccine specific IL-2 immune response @@ -165801,7 +171343,7 @@ over. vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-4 production Anthony Huffman Oliver He - vaccine-induced host response + vaccine-induced response vaccine specific interleukin-4 response @@ -165814,7 +171356,7 @@ over. vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-10 production Anthony Huffman Oliver He - vaccine-induced host response + vaccine-induced response vaccine specific interleukin-10 response @@ -165828,7 +171370,7 @@ over. Anthony Huffman Oliver He https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101669/ - vaccine-induced host response + vaccine-induced response vaccine specific Th1 immune response indicated by IgG2a production @@ -165842,7 +171384,7 @@ over. Anthony Huffman Oliver He https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101669/ - vaccine-induced host response + vaccine-induced response vaccine specific Th2 immune response indicated by IgG1 production @@ -168182,7 +173724,14 @@ over. + + + + + + + @@ -168338,7 +173887,14 @@ over. + + + + + + + A SARS DNA vaccine that is made from recombinant plasmid containing nucleocapsid protein (N) sequence constructed then expressed and purified from E. coli bacteria. Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5732 @@ -168353,7 +173909,14 @@ over. + + + + + + + A SARS DNA combination vaccine that is made from recombinant plasmids' containing membrane protein (M) and nucleocapsid protein (N) sequences constructed then expressed and purified from E. coli bacteria. Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5733 @@ -168368,7 +173931,14 @@ over. + + + + + + + A SARS DNA vaccine that is made from recombinant plasmid containing membrane protein (M) sequence constructed then expressed and purified from E. coli bacteria. Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5731 @@ -168383,7 +173953,14 @@ over. + + + + + + + A SARS DNA vaccine that is made from oral live-attenuated auxotrophic S. typhimurium aroA strain SL7207 that contained CTLA4HingeSARS800 with SARS-CoV S protein. Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5738 @@ -168399,6 +173976,7 @@ over. + @@ -168406,6 +173984,12 @@ over. + + + + + + A SARS DNA vaccine that is made from intraperitoneal recombinant spike polypeptide generated by amplififying gene encoding amino acids residues 14-667 of S protein that was cloned BamHI and KpnI sites of vector pQE-31 that was generated by Escherichia coli Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5734 @@ -168420,7 +174004,14 @@ over. + + + + + + + A SARS DNA vaccine that is made from CTLA4HingeSARS800 DNA with SARS-CoV S protein Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5737 @@ -168435,7 +174026,14 @@ over. + + + + + + + A SARS DNA vaccine that is made from tpa-optimize800 DNA with SARS-CoV S protein Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5736 @@ -168450,7 +174048,14 @@ over. + + + + + + + A SARS DNA vaccine made from CTLA4HingeSARS800 DNA with SARS-CoV S protein Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5739 @@ -168525,7 +174130,14 @@ over. + + + + + + + @@ -168561,7 +174173,14 @@ over. + + + + + + + @@ -168639,7 +174258,14 @@ over. + + + + + + + A MERS DNA vaccine made of plasmid that encoded S1 subunit only Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5715 @@ -168654,7 +174280,21 @@ over. + + + + + + + + + + + + + + A MERS combination vaccine made of made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein and a DNA vaccine that is a plasmid that encoded S1 subunit Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5717 @@ -168669,7 +174309,14 @@ over. + + + + + + + A MERS DNA vaccine made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5716 @@ -168699,7 +174346,14 @@ over. + + + + + + + A MERS DNA vaccine made of plasmid that encodes the first 725 amino acids of S from MERS-CoV Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5718 @@ -168744,7 +174398,14 @@ over. + + + + + + + @@ -168766,6 +174427,7 @@ over. + @@ -168773,6 +174435,12 @@ over. + + + + + + A recombinant SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein. Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5743 @@ -168787,7 +174455,14 @@ over. + + + + + + + A SARS VLP vaccine made from the SARS-CoV spike protein (S) and the Nucleocapsid (N), envelope (E) and membrane (M) proteins from mouse hepatitis coronavirus (MHV) Anthony Huffman VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5747 @@ -168802,7 +174477,14 @@ over. + + + + + + + @@ -168823,7 +174505,14 @@ over. + + + + + + + @@ -169404,7 +175093,14 @@ over. + + + + + + + @@ -170463,6 +176159,12 @@ over. + + + + + + @@ -170937,6 +176639,12 @@ over. + + + + + + Oliver He Philip Huang Rohit Goru @@ -170950,6 +176658,12 @@ over. + + + + + + Oliver He Philip Huang Rohit Goru @@ -170962,7 +176676,14 @@ over. + + + + + + + Oliver He Philip Huang Rohit Goru @@ -170993,7 +176714,14 @@ over. + + + + + + + Philip Huang vaccine COVID-19 DNA vaccine @@ -171004,7 +176732,14 @@ over. + + + + + + + Philip Huang vaccine COVID-19 live, attenuated vaccine @@ -171016,6 +176751,13 @@ over. + + + + + + + Philip Huang vaccine COVID-19 virus-like particle vaccine @@ -171350,6 +177092,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -171765,6 +177513,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -172032,6 +177786,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -172137,6 +177897,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -172331,6 +178097,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -172361,6 +178133,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -172391,6 +178169,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -172420,6 +178204,12 @@ https://www.ncbi.nlm.nih.gov/pubmed/?term=12 + + + + + + @@ -172614,6 +178404,12 @@ Point of Contact: Dennis Carson, UCSD + + + + + + @@ -172650,7 +178446,7 @@ Point of Contact: Dennis Carson, UCSD - + @@ -172662,7 +178458,7 @@ Point of Contact: Dennis Carson, UCSD - + @@ -173553,7 +179349,9 @@ Point of Contact: Dennis Carson, UCSD - process + Process profile that reflects a pattern of a specific immune response. + Oliver He + process profile immune response profile @@ -173568,7 +179366,7 @@ Point of Contact: Dennis Carson, UCSD Oliver He https://en.wikipedia.org/wiki/T_helper_cell https://pubmed.ncbi.nlm.nih.gov/10579123/ - process + process profile Th1-biased immune profile @@ -173583,7 +179381,7 @@ Point of Contact: Dennis Carson, UCSD Oliver He https://en.wikipedia.org/wiki/T_helper_cell https://pubmed.ncbi.nlm.nih.gov/10579123/ - process + process profile Th2-biased immune profile @@ -173598,7 +179396,7 @@ Point of Contact: Dennis Carson, UCSD Oliver He https://en.wikipedia.org/wiki/T_helper_cell https://pubmed.ncbi.nlm.nih.gov/10579123/ - process + process profile Th1/Th2 mixed immune profile @@ -173612,7 +179410,7 @@ Point of Contact: Dennis Carson, UCSD Amogh Madireddi Oliver He https://en.wikipedia.org/wiki/T_helper_17_cell - process + process profile Th17 immune profile @@ -173626,7 +179424,7 @@ Point of Contact: Dennis Carson, UCSD Amogh Madireddi Oliver He https://en.wikipedia.org/wiki/T_helper_cell - process + process profile Th1/Th17 mixed immune profile @@ -173798,6 +179596,12 @@ Point of Contact: Dennis Carson, UCSD + + + + + + @@ -173860,6 +179664,12 @@ Point of Contact: Dennis Carson, UCSD + + + + + + @@ -174160,6 +179970,12 @@ https://pubmed.ncbi.nlm.nih.gov/9013982/, https://pubmed.ncbi.nlm.nih.gov/901398 + + + + + + A recombiant vector vaccine that is has a viral vector. Anthony Huffman vaccine @@ -174482,6 +180298,12 @@ Point of Contact: Helene Bazin-Lee, InImmune + + + + + + @@ -174537,7 +180359,14 @@ Point of Contact: Helene Bazin-Lee, InImmune + + + + + + + @@ -174563,6 +180392,12 @@ Point of Contact: Helene Bazin-Lee, InImmune + + + + + + @@ -175275,7 +181110,7 @@ Point of Contact: Lisa Morici, Tulane University Oliver He https://en.wikipedia.org/wiki/T_helper_cell https://pubmed.ncbi.nlm.nih.gov/10579123/ - process + process profile Th1/Th2/Th17 mixed immune profile @@ -175868,6 +181703,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176105,6 +181946,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176155,6 +182002,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176205,6 +182058,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176317,6 +182176,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176342,6 +182207,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176367,6 +182238,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176416,6 +182293,12 @@ Point of Contact: Patrice Dubois, Vaccine Formulation Institute + + + + + + @@ -176982,6 +182865,12 @@ https://clinicaltrials.gov/ct2/show/NCT03589794 + + + + + + A Comirnaty COVID-19 mRNA vaccine produced by Pfizer-BioNTech,which is a bivalent vaccine that is effective against the original strain of COVID-19 as well as the Omicron BA.1 variant.A non-US vaccine product. Oliver He Yuanyi (Penny) Pan @@ -177001,6 +182890,12 @@ https://clinicaltrials.gov/ct2/show/NCT03589794 + + + + + + A Comirnaty COVID-19 mRNA vaccine utilizes Lipid Nanoparticle-Self-amplifying RNA technology, available as a bivalent boosters against the original strain of COVID-19 as well as the Omicron BA.1 variant produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL to provide enhanced protection. Oliver He Yuanyi (Penny) Pan @@ -177019,6 +182914,12 @@ https://clinicaltrials.gov/ct2/show/NCT03589794 + + + + + + A Comirnaty COVID-19 mRNA vaccine utilizing Lipid Nanoparticle-Self-amplifying RNA technology against the original strain of COVID-19 without preservative ,which is produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL. Oliver He Yuanyi (Penny) Pan @@ -177580,6 +183481,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -177590,6 +183492,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -177655,6 +183563,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -177668,6 +183577,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -177688,6 +183603,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -177696,6 +183612,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -177876,6 +183798,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -177911,6 +183839,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -177921,6 +183850,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -177955,6 +183890,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -177970,6 +183906,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -177998,6 +183940,7 @@ administered prior to exposure or within two weeks after exposure. + @@ -178013,6 +183956,12 @@ administered prior to exposure or within two weeks after exposure. + + + + + + @@ -178035,7 +183984,14 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + @@ -178077,24 +184033,46 @@ administered prior to exposure or within two weeks after exposure. + + + + + + + + + + + + + + + + + + + + + + @@ -179400,6 +185378,168 @@ none + + + + + Vaccine adjuvant based on VesiVax® liposome. + Chemical Nature: VesiVax® liposome +Mechanism of Action: none +Immune profile induced: none + +Route of immunization: SQ prime and IN boost, SQ, Combination sub-cheek, IN and ID, IN prime and sub-cheek boosts +Point of Contact: Gary Fujii, Molecular Express + +Pubmed References: +https://www.ncbi.nlm.nih.gov/pubmed/?term=16713037 +https://www.ncbi.nlm.nih.gov/pubmed/?term=17981684 +https://www.ncbi.nlm.nih.gov/pubmed/?term=19835825 +https://www.ncbi.nlm.nih.gov/pubmed/?term=21545821 +https://www.ncbi.nlm.nih.gov/pubmed/?term=23313243 +https://www.ncbi.nlm.nih.gov/pubmed/?term=26312747 +https://www.ncbi.nlm.nih.gov/pubmed/?term=27997339 +https://www.ncbi.nlm.nih.gov/pubmed/?term=28922045 +https://www.ncbi.nlm.nih.gov/pubmed/?term=29420901 +https://www.ncbi.nlm.nih.gov/pubmed/?term=3568049 + +Ongoing clinical trials: +none + Gary Fujii + Jie Zheng + Molecular Express + ME-F-1051 (VesiVax®) + Pubmed:16713037 + Pubmed:19835825 + Pubmed:21545821 + Pubmed:23313243 + Pubmed:26312747 + Pubmed:27997339 + Pubmed:28922045 + Pubmed:29420901 + Pubmed:3568049 + https://github.com/vaccineontology/VO/issues/784 + 104 + vaccine adjuvant + ME-F-1051 (VesiVax®) vaccine adjuvant + + + + + + + + + + + + + + + Liposome-based vaccine adjuvant with TLR4 agonist to induce a mixed Th1/Th2 response. + Chemical Nature: Natural compound - Liposome formulation with TLR4 agonist +Mechanism of Action: none +Immune profile induced: Mixed Th1/Th2 + +Route of immunization: SQ, Combination of sub-cheek, IN and ID, IN prime with sub-cheek boosts, +Point of Contact: Gary Fujii, Molecular Express + +Pubmed References: +https://www.ncbi.nlm.nih.gov/pubmed/?term=23313243 +https://www.ncbi.nlm.nih.gov/pubmed/?term=26312747 +https://www.ncbi.nlm.nih.gov/pubmed/?term=27997339 +https://www.ncbi.nlm.nih.gov/pubmed/?term=35680499 +https://www.ncbi.nlm.nih.gov/pubmed/?term=19835825 +https://www.ncbi.nlm.nih.gov/pubmed/?term=21545821 +https://www.ncbi.nlm.nih.gov/pubmed/?term=16713037 + +Ongoing clinical trials: +none + Gary Fujii + Jie Zheng + Molecular Express + ME-F-1122 + Pubmed:16713037 + Pubmed:19835825 + Pubmed:21545821 + Pubmed:23313243 + Pubmed:26312747 + Pubmed:27997339 + Pubmed:35680499 + https://github.com/vaccineontology/VO/issues/785 + 103 + vaccine adjuvant + ME-F-1122 vaccine adjuvant + + + + + + + + + + + + + + + Short class B CpG-containing sequence with phosphorothioate-linked nucleotides that is able to induce a Th1-biased response. + Chemical Nature: Nucleic acid +Mechanism of Action: CpG 1018 is a short class B CpG-containing sequence with phosphorothioate-linked nucleotides +Immune profile induced: Th1-biased + +Route of immunization: IN, IM +Point of Contact: Ben Wizel, Dynavax + +Pubmed References: +https://www.ncbi.nlm.nih.gov/pubmed/?term=24464743 +https://www.ncbi.nlm.nih.gov/pubmed/?term=33649322 +https://www.ncbi.nlm.nih.gov/pubmed/?term=33873199 +https://www.ncbi.nlm.nih.gov/pubmed/?term=33888840 +https://www.ncbi.nlm.nih.gov/pubmed/?term=38570604 +https://www.ncbi.nlm.nih.gov/pubmed/?term=35927132 +https://www.ncbi.nlm.nih.gov/pubmed/?term=35869085 +https://www.ncbi.nlm.nih.gov/pubmed/?term=37703367 +https://www.ncbi.nlm.nih.gov/pubmed/?term=39231203 + +Ongoing clinical trials: +https://clinicaltrials.gov/ct2/show/ACTRN12624000064505 +https://clinicaltrials.gov/ct2/show/NCT06334393 +https://clinicaltrials.gov/ct2/show/NCT04177355 +https://clinicaltrials.gov/ct2/show/NCT04672395 +https://clinicaltrials.gov/ct2/show/NCT05188677 +https://clinicaltrials.gov/ct2/show/NCT05011526 +https://clinicaltrials.gov/ct2/show/NCT05364242 +https://clinicaltrials.gov/ct2/show/NCT04956224 +https://clinicaltrials.gov/ct2/show/NCT0486456 +https://clinicaltrials.gov/ct2/show/ACTRN12620001177943 +https://clinicaltrials.gov/ct2/show/NCT00251394 +https://clinicaltrials.gov/ct2/show/NCT01282762 +https://clinicaltrials.gov/ct2/show/NCT00346086 +https://clinicaltrials.gov/ct2/show/NCT06569823 +https://clinicaltrials.gov/ct2/show/NCT05245838 +https://clinicaltrials.gov/ct2/show/NCT05506969 + Ben Wizel + Dynavax + Jie Zheng + CpG 1018 + Pubmed:24464743 + Pubmed:33649322 + Pubmed:33873199 + Pubmed:33888840 + Pubmed:35869085 + Pubmed:35927132 + Pubmed:37703367 + Pubmed:38570604 + Pubmed:39231203 + https://github.com/vaccineontology/VO/issues/787 + 105 + vaccine adjuvant + CpG 1018 vaccine adjuvant + + + + @@ -179417,7 +185557,14 @@ none + + + + + + + @@ -179467,7 +185614,14 @@ none + + + + + + + @@ -179542,7 +185696,14 @@ none + + + + + + + @@ -179742,7 +185903,14 @@ none + + + + + + + @@ -179992,7 +186160,14 @@ none + + + + + + + @@ -180025,7 +186200,14 @@ none + + + + + + + @@ -180058,7 +186240,14 @@ none + + + + + + + @@ -180223,6 +186412,7 @@ none + @@ -180230,6 +186420,12 @@ none + + + + + + @@ -180811,7 +187007,14 @@ none + + + + + + + @@ -180877,13 +187080,27 @@ none + + + + + + + + + + + + + + @@ -180910,7 +187127,14 @@ none + + + + + + + @@ -181012,12 +187236,12 @@ none - + - + @@ -181086,7 +187310,14 @@ none + + + + + + + @@ -181119,7 +187350,14 @@ none + + + + + + + @@ -181152,7 +187390,14 @@ none + + + + + + + @@ -181185,7 +187430,14 @@ none + + + + + + + @@ -181406,7 +187658,14 @@ none + + + + + + + @@ -181439,7 +187698,20 @@ none + + + + + + + + + + + + + @@ -181472,7 +187744,20 @@ none + + + + + + + + + + + + + @@ -181505,7 +187790,14 @@ none + + + + + + + @@ -181538,6 +187830,12 @@ none + + + + + + @@ -181570,6 +187868,12 @@ none + + + + + + @@ -181602,6 +187906,12 @@ none + + + + + + @@ -181634,6 +187944,12 @@ none + + + + + + @@ -181666,6 +187982,12 @@ none + + + + + + @@ -181698,6 +188020,12 @@ none + + + + + + @@ -181730,6 +188058,12 @@ none + + + + + + @@ -181762,6 +188096,12 @@ none + + + + + + @@ -181794,6 +188134,12 @@ none + + + + + + @@ -181826,6 +188172,12 @@ none + + + + + + @@ -181858,6 +188210,12 @@ none + + + + + + @@ -181890,6 +188248,12 @@ none + + + + + + @@ -181954,7 +188318,14 @@ none + + + + + + + @@ -181988,6 +188359,12 @@ none + + + + + + @@ -182054,6 +188431,12 @@ none + + + + + + @@ -182087,6 +188470,12 @@ none + + + + + + @@ -182120,6 +188509,12 @@ none + + + + + + @@ -182218,6 +188613,7 @@ none + @@ -182225,6 +188621,12 @@ none + + + + + + @@ -182251,6 +188653,7 @@ none + @@ -182258,6 +188661,12 @@ none + + + + + + @@ -182318,7 +188727,14 @@ none + + + + + + + @@ -182352,7 +188768,14 @@ none + + + + + + + @@ -182419,7 +188842,14 @@ none + + + + + + + @@ -182452,7 +188882,14 @@ none + + + + + + + @@ -182485,7 +188922,14 @@ none + + + + + + + @@ -182584,7 +189028,14 @@ none + + + + + + + @@ -182652,7 +189103,14 @@ none + + + + + + + @@ -184516,6 +190974,7 @@ none + @@ -184531,6 +190990,12 @@ none + + + + + + @@ -184564,6 +191029,7 @@ none + @@ -184579,6 +191045,12 @@ none + + + + + + @@ -185995,19 +192467,12 @@ none - - - - - - - @@ -188138,6 +194603,7 @@ none + @@ -188153,6 +194619,12 @@ none + + + + + + @@ -188194,6 +194666,7 @@ none + @@ -188203,6 +194676,12 @@ none + + + + + + @@ -188713,6 +195192,7 @@ none + @@ -188721,6 +195201,12 @@ none + + + + + + @@ -190503,7 +196989,7 @@ none - + @@ -190515,7 +197001,7 @@ none - + @@ -190556,6 +197042,7 @@ none + @@ -190571,6 +197058,12 @@ none + + + + + + @@ -191196,6 +197689,7 @@ none + @@ -191211,6 +197705,12 @@ none + + + + + + @@ -191505,6 +198005,7 @@ none + @@ -191520,6 +198021,12 @@ none + + + + + + @@ -192772,6 +199279,7 @@ none + @@ -192787,6 +199295,12 @@ none + + + + + + @@ -195109,6 +201623,7 @@ none + @@ -195123,6 +201638,12 @@ none + + + + + + @@ -196467,6 +202988,7 @@ none + @@ -196482,6 +203004,12 @@ none + + + + + + @@ -196838,6 +203366,7 @@ none + @@ -196852,6 +203381,12 @@ none + + + + + + @@ -196884,6 +203419,7 @@ none + @@ -196898,6 +203434,12 @@ none + + + + + + @@ -197707,6 +204249,7 @@ none + @@ -197722,6 +204265,12 @@ none + + + + + + @@ -197849,6 +204398,7 @@ none + @@ -197864,6 +204414,12 @@ none + + + + + + @@ -198158,6 +204714,7 @@ none + @@ -198173,6 +204730,12 @@ none + + + + + + @@ -198709,12 +205272,19 @@ none + + + + + + + @@ -198804,6 +205374,7 @@ none + @@ -198812,6 +205383,12 @@ none + + + + + + @@ -199131,12 +205708,19 @@ none + + + + + + + @@ -199218,6 +205802,7 @@ none + @@ -199233,6 +205818,12 @@ none + + + + + + @@ -200486,6 +207077,7 @@ none + @@ -200495,6 +207087,12 @@ none + + + + + + @@ -201133,6 +207731,7 @@ none + @@ -201146,6 +207745,12 @@ none + + + + + + @@ -201226,6 +207831,7 @@ none + @@ -201241,6 +207847,12 @@ none + + + + + + @@ -201467,6 +208079,7 @@ none + @@ -201482,6 +208095,12 @@ none + + + + + + @@ -201515,6 +208134,7 @@ none + @@ -201530,6 +208150,12 @@ none + + + + + + @@ -203161,6 +209787,7 @@ none + @@ -203169,6 +209796,12 @@ none + + + + + + @@ -203461,6 +210094,7 @@ none + @@ -203475,6 +210109,12 @@ none + + + + + + @@ -203591,6 +210231,7 @@ none + @@ -203598,6 +210239,12 @@ none + + + + + + @@ -203668,6 +210315,7 @@ none + @@ -203675,6 +210323,12 @@ none + + + + + + @@ -204272,6 +210926,7 @@ none + @@ -204282,6 +210937,12 @@ none + + + + + + @@ -204590,6 +211251,7 @@ none + @@ -204598,6 +211260,12 @@ none + + + + + + @@ -205395,12 +212063,19 @@ none + + + + + + + @@ -205544,6 +212219,7 @@ none + @@ -205551,6 +212227,12 @@ none + + + + + + @@ -207648,6 +214330,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -207656,6 +214339,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -209014,6 +215703,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -209022,6 +215712,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -209801,6 +216497,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -209808,6 +216505,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -210106,6 +216809,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -210113,6 +216817,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -210146,6 +216856,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -210153,6 +216864,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -210377,6 +217094,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -210385,6 +217103,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -210410,6 +217134,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -210418,6 +217143,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -210784,6 +217515,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -210791,6 +217523,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -212456,6 +219194,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -212463,6 +219202,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -212799,6 +219544,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -212812,6 +219558,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -214932,6 +221684,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -214941,6 +221694,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -220039,7 +226798,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220139,14 +226905,28 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + @@ -220166,8 +226946,15 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220248,6 +227035,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -220279,7 +227072,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220311,7 +227111,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220343,7 +227150,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220375,7 +227189,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220407,7 +227228,20 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + @@ -220452,13 +227286,34 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + + + + + + + + @@ -220479,7 +227334,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220706,6 +227568,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -220715,6 +227578,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -220735,6 +227604,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -220744,6 +227614,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -220764,6 +227640,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -220771,6 +227648,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -220792,12 +227675,24 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + @@ -220818,13 +227713,32 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + + + + + + @@ -220845,18 +227759,40 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + + + + + + + + + @@ -220877,18 +227813,40 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + + + + + + + + + @@ -220909,9 +227867,16 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220938,7 +227903,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220965,8 +227937,15 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -220992,7 +227971,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -221102,6 +228088,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -221109,6 +228096,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -221210,7 +228203,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -221434,7 +228434,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -221461,6 +228468,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -221468,6 +228476,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -221522,6 +228536,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -221542,7 +228562,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -221569,7 +228596,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -221596,6 +228630,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -221603,6 +228638,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -221758,7 +228799,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -221812,7 +228860,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -221919,13 +228974,27 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + @@ -221946,13 +229015,27 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + @@ -221973,13 +229056,27 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + + @@ -222000,6 +229097,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -222007,6 +229105,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -222027,6 +229131,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -222034,6 +229139,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -222136,7 +229247,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -222163,7 +229281,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -222325,7 +229450,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -222352,13 +229484,26 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + + + + + + + @@ -222414,6 +229559,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -222490,6 +229641,7 @@ Immunization Route: Intramuscular injection (i.m.) + @@ -222498,6 +229650,12 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + @@ -222573,7 +229731,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -222600,7 +229765,14 @@ Immunization Route: Intramuscular injection (i.m.) + + + + + + + @@ -226822,6 +233994,7 @@ Active immunization for the prevention of pneumonia caused by S. pneumoniae sero + @@ -226857,6 +234030,12 @@ Active immunization for the prevention of pneumonia caused by S. pneumoniae sero + + + + + + @@ -227585,6 +234764,12 @@ Active immunization for the prevention of pneumonia caused by S. pneumoniae sero + + + + + + @@ -227717,6 +234902,12 @@ Active immunization for the prevention of pneumonia caused by S. pneumoniae sero + + + + + + @@ -227915,6 +235106,7 @@ Active immunization for the prevention of pneumonia caused by S. pneumoniae sero + @@ -227933,6 +235125,12 @@ Active immunization for the prevention of pneumonia caused by S. pneumoniae sero + + + + + + @@ -230734,6 +237932,172 @@ Active immunization for the prevention of pneumonia caused by S. pneumoniae sero + + + + + Oliver He + vaccine-induced response + vaccine-induced innate immune response + + + + + + + + + Oliver He + vaccine-induced response + vaccine-induced cell-mediated immune response + + + + + + + + + An immune biomarker that indicates a humoral immune response. + Oliver He + material entity + humoral immune marker + + + + + + + + + An immune biomarker that indicates a cell-mediated immune response. + Oliver He + material entity + cell-mediated immune marker + + + + + + + + + Oliver He + PMID:22437237 + process profile + correlated profile of immune protection based on population coverage + + + + + + + + + Oliver He + PMID:22437237 + process profile + specific correlate of immune protection + + + + + + + + + Oliver He + PMID:22437237 + process profile + general correlate of immune protection + + + + + + + + + Oliver He + PMID:22437237 + process profile + correlated profile of immune protection based on statistical level + + + + + + + + + Oliver He + PMID:22437237 + process profile + cocorrelate of immune protection + + + + + + + + + Oliver He + PMID:22437237 + process profile + relative correlate of immune protection + + + + + + + + + Oliver He + PMID:22437237 + process profile + absolute correlate of immune protection + + + + + + + + + Oliver He + PMID:22437237 + process profile + correlated profile of immune protection based on causality + + + + + + + + + Oliver He + PMID:22437237 + process profile + nonmechanistic correlate of immune protection + + + + + + + + + Oliver He + PMID:22437237 + process profile + mechanistic correlate of immune protection + + + + @@ -231415,7 +238779,9 @@ immunogen: TBE + + @@ -231435,6 +238801,12 @@ immunogen: TBE + + + + + + @@ -231447,6 +238819,12 @@ immunogen: TBE + + + + + + @@ -233498,7 +240876,6 @@ immunogen: ROT - @@ -245455,7 +252832,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -245516,7 +252900,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -245573,7 +252964,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -245592,7 +252990,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -245611,7 +253016,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -245706,7 +253118,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -245744,7 +253163,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + Allen Xiang Oliver He vaccine @@ -246331,6 +253757,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -246338,6 +253765,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -246388,7 +253821,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246407,7 +253847,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246427,6 +253874,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -246445,7 +253898,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246464,7 +253924,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246538,6 +254005,13 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246599,7 +254073,21 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + + @@ -246618,7 +254106,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246714,12 +254209,19 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + Allen Xiang Oliver He vaccine @@ -246751,7 +254253,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246770,7 +254279,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246808,7 +254324,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246865,7 +254388,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246884,7 +254414,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246903,7 +254440,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246922,6 +254466,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -246929,6 +254474,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -246941,7 +254492,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246979,7 +254537,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -246998,7 +254563,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247018,12 +254590,19 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + Allen Xiang Oliver He vaccine @@ -247036,7 +254615,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + Allen Xiang Oliver He vaccine @@ -247069,12 +254655,19 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + Allen Xiang Oliver He vaccine @@ -247126,12 +254719,19 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + Allen Xiang Oliver He vaccine @@ -247144,6 +254744,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -247151,6 +254752,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -247182,7 +254789,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247214,7 +254828,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247236,7 +254857,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247255,7 +254883,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247274,7 +254909,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247312,7 +254954,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247331,7 +254980,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247350,7 +255006,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247369,7 +255032,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247445,7 +255115,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247483,6 +255160,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -247490,6 +255168,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -247521,6 +255205,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -247528,6 +255213,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -247540,6 +255231,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -247547,6 +255239,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -247560,12 +255258,19 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + Allen Xiang Oliver He vaccine @@ -247578,6 +255283,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -247595,6 +255301,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -247702,7 +255414,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247740,7 +255459,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247835,7 +255561,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247892,6 +255625,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -247899,6 +255633,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -247930,7 +255670,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247949,6 +255696,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -247956,6 +255704,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + a Coccidioides vaccine that contains C. posadasii PMP1 protein Allen Xiang Oliver He @@ -247969,7 +255723,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -247989,7 +255750,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248008,6 +255776,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248015,6 +255784,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + a Coccidioides vaccine that contains C. immitis subunit URE protein Allen Xiang Oliver He @@ -248047,7 +255822,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248066,6 +255848,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248079,6 +255862,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -248110,6 +255899,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248123,6 +255913,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -248135,7 +255931,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248173,7 +255976,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248192,7 +256002,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248263,7 +256080,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248282,7 +256106,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248320,7 +256151,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248339,7 +256177,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248457,6 +256302,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248464,6 +256310,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -248495,7 +256347,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248514,7 +256373,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248533,6 +256399,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248540,6 +256407,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + a Coccidioides vaccine that contains C. posadasii subunit GEL1 protein Allen Xiang Oliver He @@ -248553,7 +256426,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248572,6 +256452,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248579,6 +256460,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -248610,6 +256497,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248617,6 +256505,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -248686,7 +256580,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248705,7 +256606,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248724,7 +256632,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248743,6 +256658,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248750,6 +256666,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -248781,7 +256703,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -248800,6 +256729,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -248807,6 +256737,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -248968,7 +256904,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249044,6 +256987,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249051,6 +256995,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249082,6 +257032,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249089,6 +257040,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249101,7 +257058,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249120,7 +257084,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249139,7 +257110,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249158,6 +257136,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249165,6 +257144,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249177,7 +257162,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249196,7 +257188,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249215,7 +257214,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249234,7 +257240,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249253,7 +257266,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249272,7 +257292,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249343,7 +257370,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249382,6 +257416,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249389,6 +257424,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249401,7 +257442,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249420,7 +257468,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249478,7 +257533,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249497,6 +257559,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249504,6 +257567,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249568,7 +257637,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249587,7 +257663,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249606,6 +257689,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249613,6 +257697,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249625,7 +257715,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249644,6 +257741,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249651,6 +257749,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249663,7 +257767,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249682,6 +257793,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249689,6 +257801,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249701,7 +257819,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249739,6 +257864,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -249746,6 +257872,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -249758,7 +257890,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249777,7 +257916,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249828,7 +257974,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -249996,7 +258149,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein - + @@ -250087,6 +258240,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -250094,6 +258248,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -250106,6 +258266,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -250113,6 +258274,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -250125,6 +258292,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -250132,6 +258300,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + Allen Xiang Oliver He vaccine @@ -252049,6 +260223,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -252083,6 +260263,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -252124,6 +260310,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -252165,6 +260357,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -252205,6 +260403,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -252245,12 +260449,24 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -252285,13 +260501,26 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + @@ -252319,14 +260548,27 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + @@ -252398,12 +260640,30 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + + + + + + @@ -252426,12 +260686,30 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + + + + + + @@ -252450,15 +260728,36 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + + + + + + + + + @@ -252481,12 +260780,30 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + + + + + + @@ -252517,12 +260834,30 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + + + + + + @@ -252551,12 +260886,30 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + + + + + + + @@ -252659,12 +261012,24 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -252700,12 +261065,24 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -252741,12 +261118,24 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -252781,12 +261170,24 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -252852,12 +261253,24 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -252886,6 +261299,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -252920,6 +261339,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -252998,6 +261423,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -253607,6 +262038,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -253641,6 +262078,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -253682,6 +262125,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -253759,7 +262208,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -253788,6 +262244,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -253816,7 +262278,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -253845,6 +262314,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -253873,7 +262348,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -253902,6 +262384,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -253930,7 +262418,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -253962,7 +262457,14 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + @@ -253997,6 +262499,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -254046,7 +262554,9 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + @@ -254054,6 +262564,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -254082,6 +262604,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -254121,6 +262655,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -254142,7 +262688,9 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + @@ -254150,6 +262698,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -254178,6 +262738,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -254199,7 +262771,9 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + @@ -254207,6 +262781,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -254228,7 +262814,9 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + @@ -254236,6 +262824,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -254264,6 +262864,18 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + + + + + + + @@ -264897,7 +273509,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -265463,7 +274074,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -265876,7 +274486,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -266743,7 +275352,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -267746,7 +276354,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -268041,7 +276648,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -268397,7 +277003,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -268810,7 +277415,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -269376,7 +277980,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -270400,7 +279003,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -270593,7 +279195,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -270837,7 +279438,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -270901,7 +279501,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -349376,8 +357975,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -349445,8 +358042,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -349514,8 +358109,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -349583,8 +358176,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -349652,8 +358243,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -349721,8 +358310,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -349790,8 +358377,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -350841,8 +359426,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -350893,8 +359476,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -350945,8 +359526,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -350997,8 +359576,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351049,8 +359626,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351101,8 +359676,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351153,8 +359726,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351205,8 +359776,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351257,8 +359826,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351309,8 +359876,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351361,8 +359926,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351413,8 +359976,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351465,8 +360026,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351517,8 +360076,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351569,8 +360126,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -351632,8 +360187,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -355764,8 +364317,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -388717,8 +397268,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -408464,7 +417013,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -408648,7 +417196,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -408858,7 +417405,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -408974,7 +417520,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -409078,7 +417623,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -409182,9 +417726,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - @@ -409593,9 +418134,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - @@ -410015,9 +418553,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - @@ -410412,7 +418947,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -410626,7 +419160,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -410785,7 +419318,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -410811,24 +419343,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -410848,6 +419368,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein + @@ -411361,8 +419882,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -411413,8 +419932,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -411465,8 +419982,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -411889,8 +420404,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -411958,8 +420471,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -412243,8 +420754,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -415404,8 +423913,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -415456,8 +423963,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -416175,8 +424680,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -416294,8 +424797,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -416707,8 +425208,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -416770,8 +425269,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -417218,8 +425715,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -417503,8 +425998,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -420026,8 +428519,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -420218,8 +428709,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -420441,8 +428930,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424308,8 +432795,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424372,8 +432857,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424436,8 +432919,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424500,8 +432981,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424564,8 +433043,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424628,8 +433105,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424692,8 +433167,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424756,8 +433229,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424831,8 +433302,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424895,8 +433364,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -424959,8 +433426,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425023,8 +433488,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425087,8 +433550,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425151,8 +433612,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425215,8 +433674,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425279,8 +433736,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425343,8 +433798,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425407,8 +433860,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425471,8 +433922,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425535,8 +433984,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425599,8 +434046,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425663,8 +434108,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425727,8 +434170,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425791,8 +434232,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425855,8 +434294,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425919,8 +434356,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -425983,8 +434418,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -426047,8 +434480,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -426454,7 +434885,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -426568,8 +434998,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -426641,8 +435069,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -426802,8 +435228,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -426854,8 +435278,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -426912,8 +435334,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -431439,7 +439859,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -431817,7 +440236,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -432452,7 +440870,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -434222,7 +442639,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -434258,7 +442674,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -434405,7 +442820,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -434540,9 +442954,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - @@ -434864,8 +443275,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -436889,7 +445298,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -437448,8 +445856,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437513,8 +445919,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437578,8 +445982,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437643,8 +446045,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437708,8 +446108,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437773,8 +446171,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437838,8 +446234,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437903,8 +446297,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -437968,8 +446360,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438033,8 +446423,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438098,8 +446486,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438163,8 +446549,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438228,8 +446612,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438293,7 +446675,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -438351,8 +446732,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438416,8 +446795,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438481,8 +446858,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438546,8 +446921,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438611,8 +446984,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438676,8 +447047,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438741,8 +447110,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438806,8 +447173,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438871,8 +447236,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -438991,7 +447354,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -439472,8 +447834,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -439543,8 +447903,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -439614,8 +447972,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -439696,7 +448052,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -439771,7 +448126,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -441576,8 +449930,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -446593,7 +454945,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -446693,7 +455044,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -448040,7 +456390,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -448291,7 +456640,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -448553,7 +456901,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -449192,7 +457539,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -449250,7 +457596,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -449308,7 +457653,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -449366,7 +457710,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -449424,7 +457767,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -449482,7 +457824,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -456237,7 +464578,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -458183,7 +466523,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -458404,7 +466743,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -458923,7 +467261,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -458968,7 +467305,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -459357,7 +467693,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -465762,7 +474097,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -465824,7 +474158,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -466331,7 +474664,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -466552,7 +474884,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -466614,7 +474945,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -466676,7 +475006,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470505,7 +478834,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470563,7 +478891,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470621,7 +478948,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470679,7 +479005,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470737,7 +479062,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470795,7 +479119,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470853,7 +479176,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470911,7 +479233,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -470969,7 +479290,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471027,7 +479347,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471085,7 +479404,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471143,7 +479461,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471201,7 +479518,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471259,7 +479575,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471317,7 +479632,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471375,7 +479689,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471433,7 +479746,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471491,7 +479803,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471549,7 +479860,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471607,7 +479917,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471665,7 +479974,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471723,7 +480031,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471781,7 +480088,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471839,7 +480145,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471897,7 +480202,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -471955,7 +480259,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472013,7 +480316,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472071,7 +480373,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472129,7 +480430,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472187,7 +480487,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472245,7 +480544,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472303,7 +480601,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472361,7 +480658,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472419,7 +480715,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472477,7 +480772,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472535,7 +480829,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472593,7 +480886,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472651,7 +480943,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472709,7 +481000,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -472767,7 +481057,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -486315,7 +494604,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -486609,7 +494897,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -486858,7 +495145,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -487158,7 +495444,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -488353,7 +496638,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -488591,7 +496875,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -488885,7 +497168,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -489326,7 +497608,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -489705,7 +497986,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -490084,7 +498364,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -490536,7 +498815,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -490655,7 +498933,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -491096,7 +499373,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -491320,7 +499596,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -491450,7 +499725,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -496121,7 +504395,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -496179,7 +504452,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -496536,7 +504808,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -496642,7 +504913,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -496684,7 +504954,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -496747,7 +505016,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -497005,7 +505273,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -503715,7 +511982,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -513611,7 +521877,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -513688,7 +521953,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -517188,7 +525452,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -517213,24 +525476,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -517339,7 +525590,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -517364,24 +525614,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -517789,7 +526027,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -517855,7 +526092,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -519894,12 +528130,8 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - @@ -520807,7 +529039,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -522056,7 +530287,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -522315,7 +530545,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -524740,8 +532969,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -525054,8 +533281,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -525106,8 +533331,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -525295,8 +533518,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -525552,8 +533773,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -526683,8 +534902,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -527757,7 +535974,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -527815,7 +536031,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -528035,7 +536250,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -528770,7 +536984,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -528865,8 +537078,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -529100,7 +537311,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -529220,7 +537430,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -529340,7 +537549,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -553356,7 +561564,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -553582,7 +561789,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -557393,7 +565599,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -557536,7 +565741,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -557757,7 +565961,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -557827,7 +566030,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -557903,7 +566105,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -561561,7 +569762,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -569046,7 +577246,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -569091,7 +577290,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -569136,7 +577334,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -569333,7 +577530,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -570613,7 +578809,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -571360,7 +579555,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -571608,7 +579802,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -571677,7 +579870,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -572094,7 +580286,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -572119,24 +580310,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -572164,7 +580343,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -572745,7 +580923,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -572874,7 +581051,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -573031,7 +581207,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -574090,7 +582265,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -574260,7 +582434,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -574500,7 +582673,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577252,7 +585424,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577318,7 +585489,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577384,7 +585554,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577456,7 +585625,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577522,7 +585690,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577594,7 +585761,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577652,7 +585818,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577717,7 +585882,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577853,7 +586017,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -577988,7 +586151,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -578046,7 +586208,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -578104,7 +586265,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -578162,7 +586322,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -578220,7 +586379,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -578278,7 +586436,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -578336,8 +586493,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578388,8 +586543,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578496,8 +586649,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578548,8 +586699,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578600,8 +586749,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578658,8 +586805,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578766,8 +586911,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578885,8 +587028,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -578954,8 +587095,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -579076,8 +587215,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -579134,8 +587271,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -579242,8 +587377,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -579805,7 +587938,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -579949,7 +588081,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -585368,7 +593499,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -585453,7 +593583,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -585505,7 +593634,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -585557,7 +593685,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -585873,7 +594000,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -612019,7 +620145,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -612149,7 +620274,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -612544,9 +620668,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -612702,7 +620824,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -612789,7 +620910,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -612876,7 +620996,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -613211,9 +621330,7 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - @@ -621535,7 +629652,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -621705,7 +629821,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -621946,7 +630061,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -621991,7 +630105,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -622036,7 +630149,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -622081,7 +630193,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -622126,7 +630237,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -622171,7 +630281,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -622216,7 +630325,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -622261,7 +630369,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -623609,7 +631716,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -623882,7 +631988,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -624297,7 +632402,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -624570,7 +632674,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -625186,7 +633289,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -625533,7 +633635,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -626138,7 +634239,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -626765,7 +634865,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -627057,7 +635156,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -627280,7 +635378,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -628509,7 +636606,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -628683,7 +636779,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -632876,7 +640971,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -632901,24 +640995,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -632952,7 +641034,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -632977,24 +641058,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -633030,7 +641099,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -633055,24 +641123,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -633102,7 +641158,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -633127,24 +641182,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -633173,7 +641216,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -633199,24 +641241,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -633251,7 +641281,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -633277,24 +641306,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -633392,7 +641409,6 @@ Note: The 6K protein is part of the 6K-E1 structural protein - @@ -633411,24 +641427,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein - - - - - - - - - - - - @@ -633554,6 +641558,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + @@ -633596,6 +641606,12 @@ Note: The 6K protein is part of the 6K-E1 structural protein + + + + + + diff --git a/vo_terms.tsv b/vo_terms.tsv index d5c823b..0793ec1 100644 --- a/vo_terms.tsv +++ b/vo_terms.tsv @@ -285,9 +285,9 @@ "VO_0000283" "herpesvirus vaccine vector" "Class" "VO_0000284" "pMASIA DNA vaccine plasmid" "Class" "VO_0000285" "pND DNA vaccine plasmid" "Class" -"VO_0000286" "vaccine-induced host gene response" "Class" -"VO_0000287" "vaccine-induced host immune response" "Class" -"VO_0000288" "vaccine-induced host response" "Class" +"VO_0000286" "vaccine-induced gene response" "Class" +"VO_0000287" "vaccine-induced immune response" "Class" +"VO_0000288" "vaccine-induced response" "Class" "VO_0000289" "host response to vaccine adjuvant" "Class" "VO_0000290" "host response to vaccine component" "Class" "VO_0000291" "host response to vaccine antigen" "Class" @@ -308,7 +308,7 @@ "VO_0000306" "pRSV0 DNA vaccine plasmid" "Class" "VO_0000307" "KKF24" "Class" "VO_0000308" "F. tularensis vaccine LVS LPS" "Class" -"VO_0000309" "vaccine-induced antibody mediated immune response" "Class" +"VO_0000309" "obsolete vaccine-induced antibody mediated immune response" "Class" "VO_0000310" "vaccine emulsifier" "Class" "VO_0000311" "B. melitensis lipopolysaccharide vaccine" "Class" "VO_0000312" "B. melitensis LPS-GBOMP noncovalent complex vaccine" "Class" @@ -855,9 +855,9 @@ "VO_0000854" "vaccine residual" "Class" "VO_0000855" "inactivation residual in vaccine" "Class" "VO_0000856" "cell culture residual in vaccine" "Class" -"VO_0000857" "vaccine-induced immune correlate of protection" "Class" -"VO_0000858" "serologic correlate of protection" "Class" -"VO_0000859" "cell mediated immune correlate of protection" "Class" +"VO_0000857" "correlated profile of immune protection" "Class" +"VO_0000858" "serologic correlated profile of immune protection" "Class" +"VO_0000859" "cell mediated correlated profile of immune protection" "Class" "VO_0000860" "vaccine effectiveness" "Class" "VO_0000861" "Bioproperties" "NamedIndividual" "VO_0000862" "Canada" "Class" @@ -1028,7 +1028,7 @@ "VO_0001027" "Lohman Animal Health International" "NamedIndividual" "VO_0001028" "Leishmania tarentolae vaccine vector" "Class" "VO_0001029" "autologous dendritic cell melanoma vaccine" "Class" -"VO_0001030" "vaccine-induced mouse immune response" "Class" +"VO_0001030" "obsolete vaccine-induced mouse immune response" "Class" "VO_0001031" "Salmonella typhimurium SL3261 vaccine vector" "Class" "VO_0001032" "Edwardsiella tarda EIB202 vaccine vector" "Class" "VO_0001033" "Babesia bigemina vaccine" "Class" @@ -3029,8 +3029,8 @@ "VO_0003028" "human serum albumin" "Class" "VO_0003029" "gelatin vaccine stabilizer" "Class" "VO_0003030" "gelatin" "Class" -"VO_0003031" "host susceptibility gene response to vaccine adverse event" "Class" -"VO_0003032" "host immune factor-induced control of intracellular replication of live attenuated vaccine" "Class" +"VO_0003031" "susceptibility gene response to vaccine adverse event" "Class" +"VO_0003032" "immune factor-induced control of intracellular replication of live attenuated vaccine" "Class" "VO_0003033" "bovine serum albumin vaccine additive" "Class" "VO_0003034" "sugar vaccine stabilizer" "Class" "VO_0003035" "amino acid vaccine stabilizer" "Class" @@ -3043,7 +3043,7 @@ "VO_0003042" "protective vaccine antigen" "Class" "VO_0003043" "Sindbis virus vaccine" "Class" "VO_0003044" "Lymphocytic choriomeningitis virus vaccine" "Class" -"VO_0003045" "RB51 induced protection against B.suis" "Class" +"VO_0003045" "obsolete RB51 induced protection against B.suis" "Class" "VO_0003046" "Schistosoma mansoni vaccine" "Class" "VO_0003047" "Schistosoma vaccine" "Class" "VO_0003048" "vaccine-induced herd immunity" "Class" @@ -3055,18 +3055,18 @@ "VO_0003054" "intravesical vaccination" "Class" "VO_0003055" "Infectious pancreatic necrosis virus vaccine" "Class" "VO_0003056" "obsolete viral haemorrhagic septicaemia virus vaccine" "Class" -"VO_0003057" "augmented protection and cellular immunity using host protein as adjuvant" "Class" +"VO_0003057" "obsolete augmented protection and cellular immunity using host protein as adjuvant" "Class" "VO_0003058" "Mycobacterium marinum vaccine" "Class" "VO_0003059" "Hepatitis D virus vaccine" "Class" "VO_0003060" "Monkeypox virus vaccine" "Class" "VO_0003061" "Bovine viral diarrhea virus 2 vaccine" "Class" "VO_0003062" "Murid herpesvirus 1 vaccine" "Class" -"VO_0003063" "RB51 induced protection against B.abortus" "Class" -"VO_0003064" "RB51 induced protection against B.canis" "Class" -"VO_0003065" "RB51 induced protection against B.Melitensis" "Class" +"VO_0003063" "obsolete RB51 induced protection against B.abortus" "Class" +"VO_0003064" "obsolete RB51 induced protection against B.canis" "Class" +"VO_0003065" "obsolete RB51 induced protection against B.Melitensis" "Class" "VO_0003066" "Bexsero vaccine" "Class" "VO_0003067" "Flublok Quadrivalent" "Class" -"VO_0003068" "RB51 induced host immune response" "Class" +"VO_0003068" "obsolete RB51 induced host immune response" "Class" "VO_0003069" "Protein Sciences Corporation" "NamedIndividual" "VO_0003070" "Flucelvax Quadrivalent" "Class" "VO_0003071" "FluLaval Quadrivalent" "Class" @@ -3075,7 +3075,7 @@ "VO_0003074" "Fluzone Quadrivalent - Southern Hemisphere Formulation" "Class" "VO_0003075" "Gardasil 9 vaccine" "Class" "VO_0003076" "Valneva SE" "NamedIndividual" -"VO_0003077" "RB51 induced protection against B. ovis" "Class" +"VO_0003077" "obsolete RB51 induced protection against B. ovis" "Class" "VO_0003078" "Israel Institute for Biological Research" "NamedIndividual" "VO_0003079" "PaxVax, Inc." "NamedIndividual" "VO_0003080" "Nimenrix vaccine" "Class" @@ -3084,8 +3084,8 @@ "VO_0003083" "influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted by GSK" "Class" "VO_0003084" "influenza A (H1N1) 2009 Monovalent Vaccine (GlaxoSmithKline)" "Class" "VO_0003085" "Adacel-Polio" "Class" -"VO_0003086" "RB51 induced immune protection" "Class" -"VO_0003087" "RB51 induced immune response without protection" "Class" +"VO_0003086" "obsolete RB51 induced immune protection" "Class" +"VO_0003087" "obsolete RB51 induced immune response without protection" "Class" "VO_0003088" "Boostrix-Polio" "Class" "VO_0003089" "Lederle Laboratories Division" "NamedIndividual" "VO_0003090" "Tri-Immunol" "Class" @@ -5507,6 +5507,9 @@ "VO_0005509" "IL-12-MOP (CTX-1796) vaccine adjuvant" "Class" "VO_0005510" "EVAX-B vaccine adjuvant" "Class" "VO_0005511" "EVAX-S vaccine adjuvant" "Class" +"VO_0005512" "ME-F-1051 (VesiVax®) vaccine adjuvant" "Class" +"VO_0005513" "ME-F-1122 vaccine adjuvant" "Class" +"VO_0005514" "CpG 1018 vaccine adjuvant" "Class" "VO_0005561" "blocks transmission of pathogen via vaccine" "ObjectProperty" "VO_0005562" "vaccine immunity response transferrable to organism" "ObjectProperty" "VO_0005563" "microbial eukaryotic vaccine" "Class" @@ -6843,6 +6846,20 @@ "VO_0010458" "Comirnaty 2023-2024" "NamedIndividual" "VO_0010459" "Spikevax 2023-2024" "NamedIndividual" "VO_0010460" "SARS Coronavirus 2 XBB.1.5" "Class" +"VO_0010461" "vaccine-induced innate immune response" "Class" +"VO_0010462" "vaccine-induced cell-mediated immune response" "Class" +"VO_0010463" "humoral immune marker" "Class" +"VO_0010464" "cell-mediated immune marker" "Class" +"VO_0010465" "correlated profile of immune protection based on population coverage" "Class" +"VO_0010466" "specific correlate of immune protection" "Class" +"VO_0010467" "general correlate of immune protection" "Class" +"VO_0010468" "correlated profile of immune protection based on statistical level" "Class" +"VO_0010469" "cocorrelate of immune protection" "Class" +"VO_0010470" "relative correlate of immune protection" "Class" +"VO_0010471" "absolute correlate of immune protection" "Class" +"VO_0010472" "correlated profile of immune protection based on causality" "Class" +"VO_0010473" "nonmechanistic correlate of immune protection" "Class" +"VO_0010474" "mechanistic correlate of immune protection" "Class" "VO_0010632" "country" "Class" "VO_0010633" "USA" "Class" "VO_0010637" "Rubella virus vaccine" "Class"