diff --git a/client/trino-client/pom.xml b/client/trino-client/pom.xml
index e0bdce83ecf7..ff18fe62524a 100644
--- a/client/trino-client/pom.xml
+++ b/client/trino-client/pom.xml
@@ -54,6 +54,11 @@
             <artifactId>logging-interceptor</artifactId>
         </dependency>
 
+        <dependency>
+            <groupId>com.squareup.okhttp3</groupId>
+            <artifactId>okhttp-brotli</artifactId>
+        </dependency>
+
         <dependency>
             <groupId>com.squareup.okhttp3</groupId>
             <artifactId>okhttp-jvm</artifactId>
@@ -64,6 +69,11 @@
             <artifactId>okhttp-urlconnection</artifactId>
         </dependency>
 
+        <dependency>
+            <groupId>com.squareup.okhttp3</groupId>
+            <artifactId>okhttp-zstd</artifactId>
+        </dependency>
+
         <dependency>
             <groupId>dev.failsafe</groupId>
             <artifactId>failsafe</artifactId>
diff --git a/client/trino-client/src/main/java/io/trino/client/uri/HttpClientFactory.java b/client/trino-client/src/main/java/io/trino/client/uri/HttpClientFactory.java
index b882792c146d..ebe896dd2750 100644
--- a/client/trino-client/src/main/java/io/trino/client/uri/HttpClientFactory.java
+++ b/client/trino-client/src/main/java/io/trino/client/uri/HttpClientFactory.java
@@ -21,7 +21,11 @@
 import io.trino.client.auth.external.HttpTokenPoller;
 import io.trino.client.auth.external.RedirectHandler;
 import io.trino.client.auth.external.TokenPoller;
+import okhttp3.CompressionInterceptor;
+import okhttp3.Gzip;
 import okhttp3.OkHttpClient;
+import okhttp3.brotli.Brotli;
+import okhttp3.zstd.Zstd;
 
 import java.io.File;
 import java.time.Duration;
@@ -126,6 +130,10 @@ public static OkHttpClient.Builder unauthenticatedClientBuilder(TrinoUri uri, St
         setupTimeouts(builder, toIntExact(uri.getTimeout().toMillis()), TimeUnit.MILLISECONDS);
         setupHttpLogging(builder, uri.getHttpLoggingLevel());
 
+        if (!uri.isCompressionDisabled()) {
+            setupCompression(builder);
+        }
+
         if (uri.isLocalRedirectDisallowed()) {
             builder.addNetworkInterceptor(new DisallowLocalRedirectInterceptor());
         }
@@ -166,6 +174,11 @@ public static OkHttpClient.Builder unauthenticatedClientBuilder(TrinoUri uri, St
         return builder;
     }
 
+    private static void setupCompression(OkHttpClient.Builder builder)
+    {
+        builder.addInterceptor(new CompressionInterceptor(Zstd.INSTANCE, Brotli.INSTANCE, Gzip.INSTANCE));
+    }
+
     protected static void setupUserAgent(OkHttpClient.Builder builder, String userAgent)
     {
         builder.addInterceptor(userAgent(userAgent));
diff --git a/client/trino-jdbc/pom.xml b/client/trino-jdbc/pom.xml
index 110db6624cc7..08567f73372f 100644
--- a/client/trino-jdbc/pom.xml
+++ b/client/trino-jdbc/pom.xml
@@ -476,6 +476,10 @@
                                     <pattern>com.google.thirdparty</pattern>
                                     <shadedPattern>${shadeBase}.guava</shadedPattern>
                                 </relocation>
+                                <relocation>
+                                    <pattern>com.squareup</pattern>
+                                    <shadedPattern>${shadeBase}.squareup</shadedPattern>
+                                </relocation>
                                 <relocation>
                                     <pattern>io.airlift</pattern>
                                     <shadedPattern>${shadeBase}.airlift</shadedPattern>
@@ -488,6 +492,10 @@
                                     <pattern>net.bytebuddy</pattern>
                                     <shadedPattern>${shadeBase}.net.bytebuddy</shadedPattern>
                                 </relocation>
+                                <relocation>
+                                    <pattern>org.brotli</pattern>
+                                    <shadedPattern>${shadeBase}.brotli</shadedPattern>
+                                </relocation>
                                 <relocation>
                                     <pattern>org.joda.time</pattern>
                                     <shadedPattern>${shadeBase}.joda.time</shadedPattern>
diff --git a/client/trino-jdbc/src/test/java/io/trino/jdbc/JdbcDriverIT.java b/client/trino-jdbc/src/test/java/io/trino/jdbc/JdbcDriverIT.java
index c18aa7026c48..24247096766e 100644
--- a/client/trino-jdbc/src/test/java/io/trino/jdbc/JdbcDriverIT.java
+++ b/client/trino-jdbc/src/test/java/io/trino/jdbc/JdbcDriverIT.java
@@ -75,6 +75,6 @@ public void testOpenTelemetryIsNotShaded()
 
     public static boolean isExpectedFile(String filename)
     {
-        return MANIFEST_FILES.contains(filename) || filename.startsWith("io/trino/jdbc") || filename.startsWith("aircompressor/");
+        return MANIFEST_FILES.contains(filename) || filename.startsWith("io/trino/jdbc") || filename.startsWith("aircompressor/") || filename.startsWith("jni/");
     }
 }