diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index d4fb3ba005..8f4378bf4e 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -38,15 +38,41 @@ jobs:
       - name: Install Poetry
         uses: snok/install-poetry@v1
 
+      - name: Configure Poetry for CI optimization
+        run: |
+          poetry config virtualenvs.create false
+          poetry config virtualenvs.in-project false
+
+      - name: Cache Poetry dependencies
+        uses: actions/cache@v4
+        with:
+          path: ~/.cache/pypoetry
+          key: poetry-${{ runner.os }}-${{ hashFiles('**/poetry.lock') }}
+          restore-keys: |
+            poetry-${{ runner.os }}-
+
       - uses: actions/setup-node@v4
         with:
           node-version: 18
 
+      - name: Cache Nx
+        uses: actions/cache@v4
+        with:
+          path: .nx/cache
+          key: nx-${{ runner.os }}-${{ hashFiles('nx.json', 'package-lock.json') }}
+          restore-keys: |
+            nx-${{ runner.os }}-
+
       - uses: nrwl/nx-set-shas@v4
       - run: npm ci
       - run: npx nx affected -t install --with dev
       - run: npx nx affected -t lint --parallel=3
 
+      - name: Clean up build artifacts
+        run: |
+          find . -name "*.pyc" -delete
+          find . -name "__pycache__" -type d -exec rm -rf {} + || true
+
   build-packages:
     name: Build Packages
     runs-on: ubuntu-latest
@@ -66,10 +92,32 @@ jobs:
       - name: Install Poetry
         uses: snok/install-poetry@v1
 
+      - name: Configure Poetry for CI optimization
+        run: |
+          poetry config virtualenvs.create false
+          poetry config virtualenvs.in-project false
+
+      - name: Cache Poetry dependencies
+        uses: actions/cache@v4
+        with:
+          path: ~/.cache/pypoetry
+          key: poetry-${{ runner.os }}-${{ matrix.python-version }}-${{ hashFiles('**/poetry.lock') }}
+          restore-keys: |
+            poetry-${{ runner.os }}-${{ matrix.python-version }}-
+            poetry-${{ runner.os }}-
+
       - uses: actions/setup-node@v4
         with:
           node-version: 18
 
+      - name: Cache Nx
+        uses: actions/cache@v4
+        with:
+          path: .nx/cache
+          key: nx-${{ runner.os }}-${{ hashFiles('nx.json', 'package-lock.json') }}
+          restore-keys: |
+            nx-${{ runner.os }}-
+
       - uses: nrwl/nx-set-shas@v4
 
       - run: npm ci
@@ -80,6 +128,11 @@ jobs:
       - name: Build
         run: npx nx affected -t build-release --parallel=3
 
+      - name: Clean up build artifacts
+        run: |
+          find . -name "*.pyc" -delete
+          find . -name "__pycache__" -type d -exec rm -rf {} + || true
+
   test-packages:
     name: Test Packages
     runs-on: ubuntu-latest
@@ -104,10 +157,40 @@ jobs:
       - name: Install Poetry
         uses: snok/install-poetry@v1
 
+      - name: Configure Poetry for CI optimization
+        run: |
+          poetry config virtualenvs.create false
+          poetry config virtualenvs.in-project false
+
+      - name: Cache Poetry dependencies
+        uses: actions/cache@v4
+        with:
+          path: ~/.cache/pypoetry
+          key: poetry-${{ runner.os }}-${{ matrix.python-version }}-${{ hashFiles('**/poetry.lock') }}
+          restore-keys: |
+            poetry-${{ runner.os }}-${{ matrix.python-version }}-
+            poetry-${{ runner.os }}-
+
+      - name: Cache pip dependencies
+        uses: actions/cache@v4
+        with:
+          path: ~/.cache/pip
+          key: pip-${{ runner.os }}-${{ matrix.python-version }}-${{ hashFiles('**/pyproject.toml') }}
+          restore-keys: |
+            pip-${{ runner.os }}-${{ matrix.python-version }}-
+
       - uses: actions/setup-node@v4
         with:
           node-version: 18
 
+      - name: Cache Nx
+        uses: actions/cache@v4
+        with:
+          path: .nx/cache
+          key: nx-${{ runner.os }}-${{ hashFiles('nx.json', 'package-lock.json') }}
+          restore-keys: |
+            nx-${{ runner.os }}-
+
       - uses: nrwl/nx-set-shas@v4
 
       - run: npm ci
@@ -119,3 +202,8 @@ jobs:
         env:
           HAYSTACK_TELEMETRY_ENABLED: False
         run: npx nx affected -t test --exclude='sample-app' --exclude='opentelemetry-instrumentation-haystack' --parallel=3
+
+      - name: Clean up build artifacts
+        run: |
+          find . -name "*.pyc" -delete
+          find . -name "__pycache__" -type d -exec rm -rf {} + || true
diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index 336ca6c132..8506782d0b 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -63,15 +63,41 @@ jobs:
       - name: Install Poetry
         uses: snok/install-poetry@v1
 
+      - name: Configure Poetry for CI optimization
+        run: |
+          poetry config virtualenvs.create false
+          poetry config virtualenvs.in-project false
+
+      - name: Cache Poetry dependencies
+        uses: actions/cache@v4
+        with:
+          path: ~/.cache/pypoetry
+          key: poetry-${{ runner.os }}-${{ hashFiles('**/poetry.lock') }}
+          restore-keys: |
+            poetry-${{ runner.os }}-
+
       - uses: actions/setup-node@v4
         with:
           node-version: 18
 
+      - name: Cache Nx
+        uses: actions/cache@v4
+        with:
+          path: .nx/cache
+          key: nx-${{ runner.os }}-${{ hashFiles('nx.json', 'package-lock.json') }}
+          restore-keys: |
+            nx-${{ runner.os }}-
+
       - run: npm ci
 
       - name: Build Instrumentations
         run: npx nx run-many -t build-release --projects=tag:instrumentation
 
+      - name: Clean up build artifacts
+        run: |
+          find . -name "*.pyc" -delete
+          find . -name "__pycache__" -type d -exec rm -rf {} + || true
+
       - run: mkdir instrumentations-dist
       - run: cp packages/opentelemetry-instrumentation-*/dist/* instrumentations-dist
 
@@ -101,15 +127,41 @@ jobs:
       - name: Install Poetry
         uses: snok/install-poetry@v1
 
+      - name: Configure Poetry for CI optimization
+        run: |
+          poetry config virtualenvs.create false
+          poetry config virtualenvs.in-project false
+
+      - name: Cache Poetry dependencies
+        uses: actions/cache@v4
+        with:
+          path: ~/.cache/pypoetry
+          key: poetry-${{ runner.os }}-${{ hashFiles('**/poetry.lock') }}
+          restore-keys: |
+            poetry-${{ runner.os }}-
+
       - uses: actions/setup-node@v4
         with:
           node-version: 18
 
+      - name: Cache Nx
+        uses: actions/cache@v4
+        with:
+          path: .nx/cache
+          key: nx-${{ runner.os }}-${{ hashFiles('nx.json', 'package-lock.json') }}
+          restore-keys: |
+            nx-${{ runner.os }}-
+
       - run: npm ci
 
       - name: Build Traceloop SDK
         run: npx nx run traceloop-sdk:build-release
 
+      - name: Clean up build artifacts
+        run: |
+          find . -name "*.pyc" -delete
+          find . -name "__pycache__" -type d -exec rm -rf {} + || true
+
       - name: Publish release distributions to PyPI
         uses: pypa/gh-action-pypi-publish@release/v1
         with: