diff --git a/code/frameworks/react-vite/src/preset.test.ts b/code/frameworks/react-vite/src/preset.test.ts
new file mode 100644
index 000000000000..216d1db83147
--- /dev/null
+++ b/code/frameworks/react-vite/src/preset.test.ts
@@ -0,0 +1,55 @@
+import { beforeEach, describe, expect, it, vi } from 'vitest';
+
+vi.mock(import('./plugins/react-docgen.ts'), { spy: true });
+
+import * as reactDocgenModule from './plugins/react-docgen.ts';
+import { viteFinal } from './preset.ts';
+
+type ViteFinalOptions = Parameters<typeof viteFinal>[1];
+
+const createTypescriptPresetOptions = (
+  reactDocgenOptions: Record<string, unknown>
+): ViteFinalOptions =>
+  ({
+    presets: {
+      apply: async (name: string) =>
+        name === 'typescript' ? { reactDocgen: 'react-docgen', reactDocgenOptions } : undefined,
+    },
+  }) as ViteFinalOptions;
+
+describe('react-vite preset', () => {
+  beforeEach(() => {
+    vi.mocked(reactDocgenModule.reactDocgen)
+      .mockReset()
+      .mockResolvedValue({ name: 'storybook:react-docgen-plugin' });
+  });
+
+  it('passes reactDocgenOptions to the react-docgen plugin', async () => {
+    const existingPlugin = { name: 'existing-plugin' };
+    const reactDocgenOptions = {
+      exclude: [/node_modules\/.*/, /packages\/.*/],
+    };
+
+    const config = await viteFinal(
+      { plugins: [existingPlugin] },
+      createTypescriptPresetOptions(reactDocgenOptions)
+    );
+
+    expect(reactDocgenModule.reactDocgen).toHaveBeenCalledWith({
+      include: /\.(mjs|tsx?|jsx?)$/,
+      ...reactDocgenOptions,
+    });
+    expect(config.plugins).toEqual([{ name: 'storybook:react-docgen-plugin' }, existingPlugin]);
+  });
+
+  it('allows reactDocgenOptions to override the default include pattern', async () => {
+    const reactDocgenOptions = {
+      include: /\.jsx$/,
+      exclude: [/packages\/.*/],
+    };
+
+    await viteFinal({}, createTypescriptPresetOptions(reactDocgenOptions));
+
+    expect(reactDocgenModule.reactDocgen).toHaveBeenCalledWith(reactDocgenOptions);
+  });
+});
diff --git a/code/frameworks/react-vite/src/preset.ts b/code/frameworks/react-vite/src/preset.ts
index 1f752d510376..5c71a5e79835 100644
--- a/code/frameworks/react-vite/src/preset.ts
+++ b/code/frameworks/react-vite/src/preset.ts
@@ -7,14 +7,20 @@ export const core: PresetProperty<'core'> = {
   renderer: import.meta.resolve('@storybook/react/preset'),
 };
 
+type TypescriptPresetOptions = Pick<
+  NonNullable<StorybookConfig['typescript']>,
+  'reactDocgen' | 'reactDocgenOptions' | 'reactDocgenTypescriptOptions'
+>;
+
 export const viteFinal: NonNullable<StorybookConfig['viteFinal']> = async (config, { presets }) => {
   const plugins = [...(config?.plugins ?? [])];
 
   // Add docgen plugin
-  const { reactDocgen: reactDocgenOption, reactDocgenTypescriptOptions } = await presets.apply<any>(
-    'typescript',
-    {}
-  );
+  const {
+    reactDocgen: reactDocgenOption,
+    reactDocgenOptions,
+    reactDocgenTypescriptOptions,
+  } = await presets.apply<TypescriptPresetOptions>('typescript', {});
   let typescriptPresent;
 
   try {
@@ -42,6 +48,7 @@ export const viteFinal: NonNullable<StorybookConfig['viteFinal']> = async (confi
       // If react-docgen is specified, use it for everything, otherwise only use it for non-typescript files
       await reactDocgen({
         include: reactDocgenOption === 'react-docgen' ? /\.(mjs|tsx?|jsx?)$/ : /\.(mjs|jsx?)$/,
+        ...reactDocgenOptions,
       })
     );
   }
diff --git a/code/frameworks/react-vite/src/types.ts b/code/frameworks/react-vite/src/types.ts
index 938139710843..e402e8dc5316 100644
--- a/code/frameworks/react-vite/src/types.ts
+++ b/code/frameworks/react-vite/src/types.ts
@@ -7,6 +7,7 @@ import type {
 import type { BuilderOptions, StorybookConfigVite } from '@storybook/builder-vite';
 
 import type docgenTypescript from '@joshwooding/vite-plugin-react-docgen-typescript';
+import type { reactDocgen } from './plugins/react-docgen.ts';
 
 type FrameworkName = CompatibleString<'@storybook/react-vite'>;
 type BuilderName = CompatibleString<'@storybook/builder-vite'>;
@@ -26,6 +27,8 @@ export type FrameworkOptions = {
   legacyRootApi?: boolean;
 };
 
+export type ReactDocgenOptions = Parameters<typeof reactDocgen>[0];
+
 type StorybookConfigFramework = {
   framework:
     | FrameworkName
@@ -58,6 +61,8 @@ type TypescriptOptions = TypescriptOptionsBase & {
    * @default `'react-docgen'`
    */
   reactDocgen: 'react-docgen-typescript' | 'react-docgen' | false;
+  /** Configures the built-in Vite `react-docgen` plugin */
+  reactDocgenOptions: ReactDocgenOptions;
   /** Configures `@joshwooding/vite-plugin-react-docgen-typescript` */
   reactDocgenTypescriptOptions: Parameters<typeof docgenTypescript>[0];
 };
diff --git a/docs/_snippets/main-config-typescript-react-docgen-options.md b/docs/_snippets/main-config-typescript-react-docgen-options.md
new file mode 100644
index 000000000000..0366465e9470
--- /dev/null
+++ b/docs/_snippets/main-config-typescript-react-docgen-options.md
@@ -0,0 +1,33 @@
+```ts filename=".storybook/main.ts" renderer="react" language="ts" tabTitle="CSF 3"
+// Replace your-framework with the framework you are using, e.g. react-vite, nextjs, vue3-vite, etc.
+import type { StorybookConfig } from '@storybook/your-framework';
+
+const config: StorybookConfig = {
+  framework: '@storybook/your-framework',
+  stories: ['../src/**/*.mdx', '../src/**/*.stories.@(js|jsx|mjs|ts|tsx)'],
+  typescript: {
+    reactDocgen: 'react-docgen',
+    reactDocgenOptions: {
+      exclude: [/node_modules\/.*/, /packages\/.*/],
+    },
+  },
+};
+
+export default config;
+```
+
+```ts filename=".storybook/main.ts" renderer="react" language="ts" tabTitle="CSF Next 🧪"
+// Replace your-framework with the framework you are using (e.g., react-vite, nextjs, nextjs-vite)
+import { defineMain } from '@storybook/your-framework/node';
+
+export default defineMain({
+  framework: '@storybook/your-framework',
+  stories: ['../src/**/*.mdx', '../src/**/*.stories.@(js|jsx|mjs|ts|tsx)'],
+  typescript: {
+    reactDocgen: 'react-docgen',
+    reactDocgenOptions: {
+      exclude: [/node_modules\/.*/, /packages\/.*/],
+    },
+  },
+});
+```
diff --git a/docs/api/main-config/main-config-typescript.mdx b/docs/api/main-config/main-config-typescript.mdx
index c23f8e693a77..89d4a6d4f795 100644
--- a/docs/api/main-config/main-config-typescript.mdx
+++ b/docs/api/main-config/main-config-typescript.mdx
@@ -15,6 +15,10 @@ Type:
     check?: boolean;
     checkOptions?: CheckOptions;
     reactDocgen?: 'react-docgen' | 'react-docgen-typescript' | false;
+    reactDocgenOptions?: {
+      include?: string | RegExp | (string | RegExp)[];
+      exclude?: string | RegExp | (string | RegExp)[];
+    };
     reactDocgenTypescriptOptions?: ReactDocgenTypescriptOptions;
     skipCompiler?: boolean;
   }
@@ -75,6 +79,20 @@ Options to pass to `fork-ts-checker-webpack-plugin`, if [enabled](#check). See [
 
   {/* prettier-ignore-end */}
 
+  ## `reactDocgenOptions`
+
+  Type: `{ include?: string | RegExp | (string | RegExp)[]; exclude?: string | RegExp | (string | RegExp)[] }`
+
+  Available for Vite-based React projects when `reactDocgen` is enabled.
+
+  Configures the options passed to Storybook's built-in `react-docgen` Vite plugin, which can be useful in monorepos where you need to narrow the files that Storybook analyzes.
+
+  {/* prettier-ignore-start */}
+
+  <CodeSnippets path="main-config-typescript-react-docgen-options.md" />
+
+  {/* prettier-ignore-end */}
+
   ## `reactDocgenTypescriptOptions`
 
   Type: `ReactDocgenTypescriptOptions`
diff --git a/docs/configure/integration/typescript.mdx b/docs/configure/integration/typescript.mdx
index ae0a3abf9f4d..59cfadbab450 100644
--- a/docs/configure/integration/typescript.mdx
+++ b/docs/configure/integration/typescript.mdx
@@ -43,6 +43,7 @@ See the [main configuration API reference](../../api/main-config/main-config.mdx
   | `check`                        | Available for Webpack-based projects.<br />Enables type checking within Storybook<br />`typescript: { check: true },`                                                                                                                       |
   | `checkOptions`                 | Requires the `check` option to be enabled.<br />Configures the [`fork-ts-checker-webpack-plugin`](https://github.com/TypeStrong/fork-ts-checker-webpack-plugin) plugin<br />`typescript: { checkOptions: {},},`                             |
   | `reactDocgen`                  | Configures the TypeScript parser used by Storybook.<br />Available options: `react-docgen` (default), `react-docgen-typescript`,` false`<br /> `typescript: { reactDocgen: 'react-docgen'},`                                                |
+  | `reactDocgenOptions`           | Available for Vite-based React projects when `reactDocgen` is enabled.<br />Configures Storybook's built-in `react-docgen` Vite plugin, including custom `include` and `exclude` filters.<br />`typescript: { reactDocgen: 'react-docgen', reactDocgenOptions: {},},` |
   | `reactDocgenTypescriptOptions` | Requires the `reactDocgen`option to be `react-docgen-typescript`.<br /> Configures the `react-docgen-typescript-plugin` plugin per builder<br />`typescript: { reactDocgen: 'react-docgen-typescript', reactDocgenTypescriptOptions: {},},` |
   | `skipCompiler`                 | Disables parsing Typescript files through the compiler<br />`typescript: { skipCompiler:false,},`                                                                                                                                           |
 </IfRenderer>