diff --git a/packages/react-native-reanimated/__tests__/InterpolateColor.test.tsx b/packages/react-native-reanimated/__tests__/InterpolateColor.test.tsx
index 01ef7a3c4fbf..c44f49b916a0 100644
--- a/packages/react-native-reanimated/__tests__/InterpolateColor.test.tsx
+++ b/packages/react-native-reanimated/__tests__/InterpolateColor.test.tsx
@@ -123,6 +123,14 @@ describe('colors interpolation', () => {
     expect(interpolatedColor).toBe(`rgba(96, 144, 32, ${112 / 255})`);
   });
 
+  it('handles tiny values', () => {
+    const colors = ['#00000000', '#ff802001'];
+
+    // We don't want output like "rgba(4, 2, 0, 3.921568627450981e-7)":
+    const interpolatedColor = interpolateColor(0.0001, [0, 1], colors);
+    expect(interpolatedColor).toBe(`rgba(4, 2, 0, 0)`);
+  });
+
   function TestComponent() {
     const color = useSharedValue('#105060');
 
diff --git a/packages/react-native-reanimated/src/Colors.ts b/packages/react-native-reanimated/src/Colors.ts
index 2b01b32668ae..cd577a68c543 100644
--- a/packages/react-native-reanimated/src/Colors.ts
+++ b/packages/react-native-reanimated/src/Colors.ts
@@ -522,7 +522,9 @@ export const rgbaColor = (
 ): number | string => {
   'worklet';
   if (IS_WEB || !_WORKLET) {
-    return `rgba(${r}, ${g}, ${b}, ${alpha})`;
+    // Replace tiny values like 1.234e-11 with 0:
+    const safeAlpha = alpha < 0.001 ? 0 : alpha;
+    return `rgba(${r}, ${g}, ${b}, ${safeAlpha})`;
   }
 
   const c =
@@ -701,9 +703,10 @@ export function convertToRGBA(color: unknown): ParsedColorArray {
 
 export function rgbaArrayToRGBAColor(RGBA: ParsedColorArray): string {
   'worklet';
+  const alpha = RGBA[3] < 0.001 ? 0 : RGBA[3];
   return `rgba(${Math.round(RGBA[0] * 255)}, ${Math.round(
     RGBA[1] * 255
-  )}, ${Math.round(RGBA[2] * 255)}, ${RGBA[3]})`;
+  )}, ${Math.round(RGBA[2] * 255)}, ${alpha})`;
 }
 
 export function toLinearSpace(