Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

HHblits run stuck at the prefiltering stage #381

Open
rayab1993 opened this issue Jan 29, 2025 · 0 comments
Open

HHblits run stuck at the prefiltering stage #381

rayab1993 opened this issue Jan 29, 2025 · 0 comments

Comments

@rayab1993
Copy link

rayab1993 commented Jan 29, 2025

Dear Authors,
I am having an issue from last couple of weeks for which I am unable to run hhblits_mpi for a list of protein sequences with UNICLUST30 as database:

My hhblits command is as follows:

mpirun hhblits_mpi -i ARDB -d "$DB" -oa3m ARDB_a3m -n 2 -cpu 48 -v 2

However the program is stuck at the prefiltering stage and never finishes the a3m files:

  • 14:49:05.541 INFO: Prefiltering database

  • 14:49:05.558 INFO: Prefiltering database

  • 14:49:05.580 INFO: Prefiltering database

  • 14:49:05.648 INFO: Prefiltering database

  • 14:49:05.666 INFO: Prefiltering database

  • 14:49:06.060 INFO: Searching 36293491 column state sequences.

  • 14:49:06.125 INFO: AR0080 is in A2M, A3M or FASTA format

  • 14:49:06.125 INFO: Iteration 1

  • 14:49:06.144 INFO: Searching 36293491 column state sequences.

  • 14:49:06.200 INFO: Searching 36293491 column state sequences.

  • 14:49:06.208 INFO: AR0087 is in A2M, A3M or FASTA format

  • 14:49:06.208 INFO: Iteration 1

  • 14:49:06.216 INFO: Prefiltering database

  • 14:49:06.264 INFO: AR0093 is in A2M, A3M or FASTA format

  • 14:49:06.265 INFO: Iteration 1

  • 14:49:06.281 INFO: Prefiltering database

  • 14:49:06.337 INFO: Prefiltering database

After this part the program doesnt seem to do anything.

The alignment files are all blank

Just to be clear , my input is a series of unrelated sequences in ffindex,ffdata format

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant