diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index b4ab973ea7..92f145542f 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -143,6 +143,69 @@ jobs:
           popd &>/dev/null
         done
 
+  # We make sure that Smithy-rs can be compiled on platforms that are not natively supported by GitHub actions.
+  # We do not run tests on those platforms (yet) because it'd require a more complicated setup involving architecture
+  # emulation via QEMU, likely to cause a significant degradation on CI completion time.
+  test-exotic-platform-support:
+    name: Exotic platform support
+    runs-on: ubuntu-latest
+    strategy:
+      fail-fast: false
+      matrix:
+        include:
+        - target: i686-unknown-linux-gnu
+          non_aws_features: --all-features
+          aws_excludes: ''
+        # We only test `native-tls` here because `rustls` depends on `ring` which in turn does not support powerpc
+        # as a target platform (see https://github.com/briansmith/ring/issues/389)
+        # We also exclude all first-party crates that have a non-optional dependency on `ring`.
+        - target: powerpc-unknown-linux-gnu
+          non_aws_features: --features native-tls
+          aws_excludes: --exclude aws-inlineable --exclude aws-sigv4 --exclude aws-sig-auth
+    env:
+      CROSS_CONFIG: Cross.toml
+      OPENSSL_LIB_DIR: /usr/lib/i386-linux-gnu
+      OPENSSL_INCLUDE_DIR: /usr/include/i386-linux-gnu
+    steps:
+    - name: Checkout
+      uses: actions/checkout@v1
+      # Pinned to the commit hash of v1.3.0
+    - uses: Swatinem/rust-cache@842ef286fff290e445b90b4002cc9807c3669641
+      with:
+        sharedKey: ${{ runner.os }}-${{ env.rust_version }}-${{ github.job }}-${{ matrix.target }}
+        target-dir: ./target
+    - uses: actions-rs/toolchain@v1
+      with:
+        toolchain: ${{ env.rust_version }}
+        components: ${{ env.rust_toolchain_components }}
+        profile: minimal
+        override: true
+        target: ${{ matrix.target }}
+    - name: Configure cross
+      shell: bash
+      run: |
+        cat > Cross.toml << EOF
+        [build]
+        pre-build = ["dpkg --add-architecture i386", "apt-get update && apt-get install --assume-yes pkg-config:i386 libssl-dev:i386"]
+        [build.env]
+        passthrough = [
+            "OPENSSL_LIB_DIR",
+            "OPENSSL_INCLUDE_DIR",
+        ]
+        EOF
+    - name: Build rust-runtime crates
+      uses: actions-rs/cargo@v1
+      with:
+        use-cross: true
+        command: build
+        args: --target ${{ matrix.target }} --manifest-path "rust-runtime/Cargo.toml" --exclude aws-smithy-http-server-python --workspace ${{ matrix.non_aws_features }}
+    - name: Build AWS rust-runtime crates
+      uses: actions-rs/cargo@v1
+      with:
+        use-cross: true
+        command: build
+        args: --target ${{ matrix.target }} --manifest-path "aws/rust-runtime/Cargo.toml" ${{ matrix.aws_excludes }} --workspace
+
   # This job is split out from the rest since it is not required to pass for merge
   check-sdk-examples:
     name: Check SDK Examples
@@ -166,6 +229,7 @@ jobs:
     - test-codegen
     - test-sdk
     - test-rust-windows
+    - test-exotic-platform-support
     # Run this job even if its dependency jobs fail
     if: always()
     runs-on: ubuntu-latest
diff --git a/CODEOWNERS b/CODEOWNERS
index 19506644ac..20265881e6 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -7,6 +7,7 @@
 /rust-runtime/aws-smithy-http-server/           @awslabs/smithy-rs-server
 
 # Shared ownership
+/.github/                                       @awslabs/rust-sdk-owners @awslabs/smithy-rs-server
 /CHANGELOG.md                                   @awslabs/rust-sdk-owners @awslabs/smithy-rs-server
 /CHANGELOG.next.toml                            @awslabs/rust-sdk-owners @awslabs/smithy-rs-server
 /README.md                                      @awslabs/rust-sdk-owners @awslabs/smithy-rs-server
diff --git a/rust-runtime/aws-smithy-client/additional-ci b/rust-runtime/aws-smithy-client/additional-ci
index c1fd7ce406..fde542e9fc 100755
--- a/rust-runtime/aws-smithy-client/additional-ci
+++ b/rust-runtime/aws-smithy-client/additional-ci
@@ -10,3 +10,6 @@ set -e
 
 echo "### Checking for duplicate dependency versions in the normal dependency graph with all features enabled"
 cargo tree -d --edges normal --all-features
+
+echo "### Testing every combination of features (excluding --all-features)"
+cargo hack test --feature-powerset --exclude-all-features
diff --git a/rust-runtime/aws-smithy-client/src/builder.rs b/rust-runtime/aws-smithy-client/src/builder.rs
index 017ae04e7b..4a1b62fb85 100644
--- a/rust-runtime/aws-smithy-client/src/builder.rs
+++ b/rust-runtime/aws-smithy-client/src/builder.rs
@@ -135,7 +135,7 @@ impl<M, R> Builder<(), M, R> {
         let with_https = |b: Builder<_, M, R>| b.rustls_connector(connector_settings);
         // If we are compiling this function & rustls is not enabled, then native-tls MUST be enabled
         #[cfg(not(feature = "rustls"))]
-        let with_https = |b: Builder<_, M, R>| b.native_tls_connector();
+        let with_https = |b: Builder<_, M, R>| b.native_tls_connector(connector_settings);
 
         with_https(self)
     }
diff --git a/rust-runtime/aws-smithy-client/src/hyper_ext.rs b/rust-runtime/aws-smithy-client/src/hyper_ext.rs
index 18acf75526..27caf43ad3 100644
--- a/rust-runtime/aws-smithy-client/src/hyper_ext.rs
+++ b/rust-runtime/aws-smithy-client/src/hyper_ext.rs
@@ -17,7 +17,20 @@
 //! with `rustls` will be constructed during client creation. However, if you are creating a Smithy
 //! [`Client`](crate::Client), directly, use the `dyn_https_https()` method to match that default behavior:
 //!
-//! ```no_run
+#![cfg_attr(
+    not(all(
+        any(feature = "rustls", feature = "native-tls"),
+        feature = "client-hyper"
+    )),
+    doc = "```no_run,ignore"
+)]
+#![cfg_attr(
+    all(
+        any(feature = "rustls", feature = "native-tls"),
+        feature = "client-hyper"
+    ),
+    doc = "```no_run"
+)]
 //! use aws_smithy_client::Client;
 //!
 //! let client = Client::builder()
@@ -34,7 +47,11 @@
 //! A use case for where you may want to use the [`Adapter`] is when settings Hyper client settings
 //! that aren't otherwise exposed by the `Client` builder interface.
 //!
-//! ```no_run
+#![cfg_attr(
+    not(all(feature = "rustls", feature = "client-hyper")),
+    doc = "```no_run,ignore"
+)]
+#![cfg_attr(all(feature = "rustls", feature = "client-hyper"), doc = "```no_run")]
 //! use std::time::Duration;
 //! use aws_smithy_client::{Client, conns, hyper_ext};
 //! use aws_smithy_client::erase::DynConnector;
@@ -186,7 +203,11 @@ fn find_source<'a, E: Error + 'static>(err: &'a (dyn Error + 'static)) -> Option
 /// Construct a HyperAdapter with the default HTTP implementation (rustls). This can be useful when you want to share a Hyper connector
 /// between multiple Smithy clients.
 ///
-/// ```no_run
+#[cfg_attr(
+    not(all(feature = "rustls", feature = "client-hyper")),
+    doc = "```no_run,ignore"
+)]
+#[cfg_attr(all(feature = "rustls", feature = "client-hyper"), doc = "```no_run")]
 /// use tower::layer::util::Identity;
 /// use aws_smithy_client::{conns, hyper_ext};
 /// use aws_smithy_client::erase::DynConnector;
@@ -428,7 +449,7 @@ mod timeout_middleware {
         fn poll(self: Pin<&mut Self>, cx: &mut Context<'_>) -> Poll<Self::Output> {
             let (timeout_future, kind, &mut duration) = match self.project() {
                 MaybeTimeoutFutureProj::NoTimeout { future } => {
-                    return future.poll(cx).map_err(|err| err.into())
+                    return future.poll(cx).map_err(|err| err.into());
                 }
                 MaybeTimeoutFutureProj::Timeout {
                     timeout,