diff --git a/ndk-build/CHANGELOG.md b/ndk-build/CHANGELOG.md
index 3d7c9514..e2288961 100644
--- a/ndk-build/CHANGELOG.md
+++ b/ndk-build/CHANGELOG.md
@@ -1,6 +1,7 @@
 # Unreleased
 
 - Allow NDK r23 `-lgcc` workaround to work for target directories containing spaces. ([#298](https://github.com/rust-windowing/android-ndk-rs/pull/298))
+- Invoke `clang` directly instead of through the NDK's wrapper scripts. ([#306](https://github.com/rust-windowing/android-ndk-rs/pull/306))
 
 # 0.6.0 (2022-06-11)
 
diff --git a/ndk-build/src/apk.rs b/ndk-build/src/apk.rs
index 1610a4e6..2ba1e047 100644
--- a/ndk-build/src/apk.rs
+++ b/ndk-build/src/apk.rs
@@ -116,7 +116,7 @@ impl<'a> UnalignedApk<'a> {
         search_paths: &[&Path],
     ) -> Result<(), NdkError> {
         let abi_dir = path.join(target.android_abi());
-        for entry in fs::read_dir(&abi_dir).map_err(|e| NdkError::IoPathError(e, abi_dir))? {
+        for entry in fs::read_dir(&abi_dir).map_err(|e| NdkError::IoPathError(abi_dir, e))? {
             let entry = entry?;
             let path = entry.path();
             if path.extension() == Some(OsStr::new("so")) {
diff --git a/ndk-build/src/cargo.rs b/ndk-build/src/cargo.rs
index d46474d5..0203e73a 100644
--- a/ndk-build/src/cargo.rs
+++ b/ndk-build/src/cargo.rs
@@ -11,12 +11,34 @@ pub fn cargo_ndk(
     target_dir: impl AsRef<Path>,
 ) -> Result<Command, NdkError> {
     let triple = target.rust_triple();
+    let clang_target = format!("--target={}{}", target.ndk_llvm_triple(), sdk_version);
     let mut cargo = Command::new("cargo");
 
-    let (clang, clang_pp) = ndk.clang(target, sdk_version)?;
+    // Read initial RUSTFLAGS
+    let mut rustflags = match std::env::var("CARGO_ENCODED_RUSTFLAGS") {
+        Ok(val) => val,
+        Err(std::env::VarError::NotPresent) => "".to_string(),
+        Err(std::env::VarError::NotUnicode(_)) => {
+            panic!("RUSTFLAGS environment variable contains non-unicode characters")
+        }
+    };
+
+    let (clang, clang_pp) = ndk.clang()?;
+
+    // Configure cross-compiler for `cc` crate
+    // https://github.com/rust-lang/cc-rs#external-configuration-via-environment-variables
     cargo.env(format!("CC_{}", triple), &clang);
+    cargo.env(format!("CFLAGS_{}", triple), &clang_target);
     cargo.env(format!("CXX_{}", triple), &clang_pp);
+    cargo.env(format!("CXXFLAGS_{}", triple), &clang_target);
+
+    // Configure LINKER for `rustc`
+    // https://doc.rust-lang.org/beta/cargo/reference/environment-variables.html#configuration-environment-variables
     cargo.env(cargo_env_target_cfg("LINKER", triple), &clang);
+    if !rustflags.is_empty() {
+        rustflags.push('\x1f');
+    }
+    rustflags.push_str(&format!("-Clink-arg={}", clang_target));
 
     let ar = ndk.toolchain_bin("ar", target)?;
     cargo.env(format!("AR_{}", triple), &ar);
@@ -32,32 +54,28 @@ pub fn cargo_ndk(
         let cargo_apk_link_dir = target_dir
             .as_ref()
             .join("cargo-apk-temp-extra-link-libraries");
-        std::fs::create_dir_all(&cargo_apk_link_dir)?;
-        std::fs::write(cargo_apk_link_dir.join("libgcc.a"), "INPUT(-lunwind)")
-            .expect("Failed to write");
+        std::fs::create_dir_all(&cargo_apk_link_dir)
+            .map_err(|e| NdkError::IoPathError(cargo_apk_link_dir.clone(), e))?;
+        let libgcc = cargo_apk_link_dir.join("libgcc.a");
+        std::fs::write(&libgcc, "INPUT(-lunwind)").map_err(|e| NdkError::IoPathError(libgcc, e))?;
 
         // cdylibs in transitive dependencies still get built and also need this
         // workaround linker flag, yet arguments passed to `cargo rustc` are only
         // forwarded to the final compiler invocation rendering our workaround ineffective.
         // The cargo page documenting this discrepancy (https://doc.rust-lang.org/cargo/commands/cargo-rustc.html)
-        // suggests to resort to RUSTFLAGS, which are updated below:
-        let mut rustflags = match std::env::var("CARGO_ENCODED_RUSTFLAGS") {
-            Ok(val) => val,
-            Err(std::env::VarError::NotPresent) => "".to_string(),
-            Err(std::env::VarError::NotUnicode(_)) => {
-                panic!("RUSTFLAGS environment variable contains non-unicode characters")
-            }
-        };
-        if !rustflags.is_empty() {
-            rustflags.push('\x1f');
-        }
-        rustflags += "-L\x1f";
-        rustflags += cargo_apk_link_dir
-            .to_str()
-            .expect("Target dir must be valid UTF-8");
-        cargo.env("CARGO_ENCODED_RUSTFLAGS", rustflags);
+        // suggests to resort to RUSTFLAGS.
+        // Note that `rustflags` will never be empty because of an unconditional `.push_str` above,
+        // so we can safely start with appending \x1f here.
+        rustflags.push_str("\x1f-L\x1f");
+        rustflags.push_str(
+            cargo_apk_link_dir
+                .to_str()
+                .expect("Target dir must be valid UTF-8"),
+        );
     }
 
+    cargo.env("CARGO_ENCODED_RUSTFLAGS", rustflags);
+
     Ok(cargo)
 }
 
diff --git a/ndk-build/src/error.rs b/ndk-build/src/error.rs
index 7fa08cf9..2055300f 100644
--- a/ndk-build/src/error.rs
+++ b/ndk-build/src/error.rs
@@ -39,8 +39,8 @@ pub enum NdkError {
     UnsupportedHost(String),
     #[error(transparent)]
     Io(#[from] IoError),
-    #[error("{0:?}: `{1}`")]
-    IoPathError(#[source] IoError, PathBuf),
+    #[error("IoError on `{0:?}`: {1}")]
+    IoPathError(PathBuf, #[source] IoError),
     #[error("Invalid semver")]
     InvalidSemver,
     #[error("Command `{}` had a non-zero exit code.", format!("{:?}", .0).replace('"', ""))]
diff --git a/ndk-build/src/lib.rs b/ndk-build/src/lib.rs
index 2f556c9f..a4323002 100644
--- a/ndk-build/src/lib.rs
+++ b/ndk-build/src/lib.rs
@@ -1,21 +1,21 @@
 macro_rules! bin {
-    ($bin:expr) => {{
-        #[cfg(not(target_os = "windows"))]
-        let bin = $bin;
-        #[cfg(target_os = "windows")]
-        let bin = concat!($bin, ".exe");
-        bin
-    }};
+    ($bin:expr) => {
+        if cfg!(target_os = "windows") {
+            concat!($bin, ".exe")
+        } else {
+            $bin
+        }
+    };
 }
 
 macro_rules! bat {
-    ($bat:expr) => {{
-        #[cfg(not(target_os = "windows"))]
-        let bat = $bat;
-        #[cfg(target_os = "windows")]
-        let bat = concat!($bat, ".bat");
-        bat
-    }};
+    ($bat:expr) => {
+        if cfg!(target_os = "windows") {
+            concat!($bat, ".bat")
+        } else {
+            $bat
+        }
+    };
 }
 
 pub mod apk;
diff --git a/ndk-build/src/ndk.rs b/ndk-build/src/ndk.rs
index 5035aecf..3b3a2a10 100644
--- a/ndk-build/src/ndk.rs
+++ b/ndk-build/src/ndk.rs
@@ -228,21 +228,21 @@ impl Ndk {
         Ok(toolchain_dir)
     }
 
-    pub fn clang(&self, target: Target, platform: u32) -> Result<(PathBuf, PathBuf), NdkError> {
-        #[cfg(target_os = "windows")]
-        let ext = ".cmd";
-        #[cfg(not(target_os = "windows"))]
-        let ext = "";
+    pub fn clang(&self) -> Result<(PathBuf, PathBuf), NdkError> {
+        let ext = if cfg!(target_os = "windows") {
+            "exe"
+        } else {
+            ""
+        };
 
-        let bin_name = format!("{}{}-clang", target.ndk_llvm_triple(), platform);
         let bin_path = self.toolchain_dir()?.join("bin");
 
-        let clang = bin_path.join(format!("{}{}", &bin_name, ext));
+        let clang = bin_path.join("clang").with_extension(ext);
         if !clang.exists() {
             return Err(NdkError::PathNotFound(clang));
         }
 
-        let clang_pp = bin_path.join(format!("{}++{}", &bin_name, ext));
+        let clang_pp = bin_path.join("clang++").with_extension(ext);
         if !clang_pp.exists() {
             return Err(NdkError::PathNotFound(clang_pp));
         }
@@ -251,10 +251,11 @@ impl Ndk {
     }
 
     pub fn toolchain_bin(&self, name: &str, target: Target) -> Result<PathBuf, NdkError> {
-        #[cfg(target_os = "windows")]
-        let ext = ".exe";
-        #[cfg(not(target_os = "windows"))]
-        let ext = "";
+        let ext = if cfg!(target_os = "windows") {
+            ".exe"
+        } else {
+            ""
+        };
 
         let toolchain_path = self.toolchain_dir()?.join("bin");