diff --git a/compiler/rustc_target/src/asm/mod.rs b/compiler/rustc_target/src/asm/mod.rs
index df13d24cb9e21..73ae1ae96ae23 100644
--- a/compiler/rustc_target/src/asm/mod.rs
+++ b/compiler/rustc_target/src/asm/mod.rs
@@ -893,6 +893,7 @@ pub enum InlineAsmClobberAbi {
     RiscV,
     LoongArch,
     S390x,
+    Msp430,
 }
 
 impl InlineAsmClobberAbi {
@@ -946,6 +947,10 @@ impl InlineAsmClobberAbi {
                 "C" | "system" => Ok(InlineAsmClobberAbi::S390x),
                 _ => Err(&["C", "system"]),
             },
+            InlineAsmArch::Msp430 => match name {
+                "C" | "system" => Ok(InlineAsmClobberAbi::Msp430),
+                _ => Err(&["C", "system"]),
+            },
             _ => Err(&[]),
         }
     }
@@ -1125,6 +1130,11 @@ impl InlineAsmClobberAbi {
                     a8, a9, a10, a11, a12, a13, a14, a15,
                 }
             },
+            InlineAsmClobberAbi::Msp430 => clobbered_regs! {
+                Msp430 Msp430InlineAsmReg {
+                    r11, r12, r13, r14, r15,
+                }
+            },
         }
     }
 }
diff --git a/tests/codegen/asm-msp430-clobbers.rs b/tests/codegen/asm-msp430-clobbers.rs
new file mode 100644
index 0000000000000..c00c04f3088cb
--- /dev/null
+++ b/tests/codegen/asm-msp430-clobbers.rs
@@ -0,0 +1,36 @@
+//@ assembly-output: emit-asm
+//@ compile-flags: --target msp430-none-elf
+//@ needs-llvm-components: msp430
+
+#![crate_type = "rlib"]
+#![feature(no_core, rustc_attrs, lang_items, asm_experimental_arch)]
+#![no_core]
+
+#[lang = "sized"]
+trait Sized {}
+
+#[rustc_builtin_macro]
+macro_rules! asm {
+    () => {};
+}
+
+// CHECK-LABEL: @sr_clobber
+// CHECK: call void asm sideeffect "", "~{sr}"()
+#[no_mangle]
+pub unsafe fn sr_clobber() {
+    asm!("", options(nostack, nomem));
+}
+
+// CHECK-LABEL: @no_clobber
+// CHECK: call void asm sideeffect "", ""()
+#[no_mangle]
+pub unsafe fn no_clobber() {
+    asm!("", options(nostack, nomem, preserves_flags));
+}
+
+// CHECK-LABEL: @clobber_abi
+// CHECK: asm sideeffect "", "={r11},={r12},={r13},={r14},={r15}"()
+#[no_mangle]
+pub unsafe fn clobber_abi() {
+    asm!("", clobber_abi("C"), options(nostack, nomem, preserves_flags));
+}