diff --git a/lib/modules/manager/mise/extract.spec.ts b/lib/modules/manager/mise/extract.spec.ts
index 94490592d39..1cc1fd49c0f 100644
--- a/lib/modules/manager/mise/extract.spec.ts
+++ b/lib/modules/manager/mise/extract.spec.ts
@@ -71,6 +71,7 @@ describe('modules/manager/mise/extract', () => {
       lefthook = "1.11.13"
       localstack = "4.3.0"
       lychee = "0.19.1"
+      neo4j = "2026.04.0"
       npm = "11.2.0"
       opentofu = "1.6.1"
       openfga = "1.14.0"
@@ -235,6 +236,12 @@ describe('modules/manager/mise/extract', () => {
             extractVersion: '^lychee-v(?<version>\\S+)',
             packageName: 'lycheeverse/lychee',
           },
+          {
+            currentValue: '2026.04.0',
+            datasource: 'maven',
+            depName: 'neo4j',
+            packageName: 'org.neo4j:neo4j',
+          },
           {
             currentValue: '11.2.0',
             datasource: 'npm',
diff --git a/lib/modules/manager/mise/index.ts b/lib/modules/manager/mise/index.ts
index a714328e9b1..5275bba07a3 100644
--- a/lib/modules/manager/mise/index.ts
+++ b/lib/modules/manager/mise/index.ts
@@ -6,6 +6,7 @@ import { GithubReleasesDatasource } from '../../datasource/github-releases/index
 import { GithubTagsDatasource } from '../../datasource/github-tags/index.ts';
 import { GoDatasource } from '../../datasource/go/index.ts';
 import { JavaVersionDatasource } from '../../datasource/java-version/index.ts';
+import { MavenDatasource } from '../../datasource/maven/index.ts';
 import { NodeVersionDatasource } from '../../datasource/node-version/index.ts';
 import { NpmDatasource } from '../../datasource/npm/index.ts';
 import { NugetDatasource } from '../../datasource/nuget/index.ts';
@@ -35,6 +36,7 @@ const backendDatasources = {
     GithubReleasesDatasource.id,
     GithubTagsDatasource.id,
     JavaVersionDatasource.id,
+    MavenDatasource.id,
     NodeVersionDatasource.id,
     RubyVersionDatasource.id,
   ],
diff --git a/lib/modules/manager/mise/upgradeable-tooling.ts b/lib/modules/manager/mise/upgradeable-tooling.ts
index 699d2154d30..c3a47aa61e0 100644
--- a/lib/modules/manager/mise/upgradeable-tooling.ts
+++ b/lib/modules/manager/mise/upgradeable-tooling.ts
@@ -4,6 +4,7 @@ import { GithubReleasesDatasource } from '../../datasource/github-releases/index
 import { GithubTagsDatasource } from '../../datasource/github-tags/index.ts';
 import { HexpmBobDatasource } from '../../datasource/hexpm-bob/index.ts';
 import { JavaVersionDatasource } from '../../datasource/java-version/index.ts';
+import { MavenDatasource } from '../../datasource/maven/index.ts';
 import { NodeVersionDatasource } from '../../datasource/node-version/index.ts';
 import { NpmDatasource } from '../../datasource/npm/index.ts';
 import { RubyVersionDatasource } from '../../datasource/ruby-version/index.ts';
@@ -364,6 +365,13 @@ const miseRegistryTooling: Record<string, ToolingDefinition> = {
       extractVersion: '^lychee-v(?<version>\\S+)',
     },
   },
+  neo4j: {
+    misePluginUrl: 'https://mise.jdx.dev/registry.html#tools',
+    config: {
+      packageName: 'org.neo4j:neo4j',
+      datasource: MavenDatasource.id,
+    },
+  },
   npm: {
     misePluginUrl: 'https://mise.jdx.dev/registry.html#tools',
     config: {