diff --git a/.buildkite/test.rules.test.txt b/.buildkite/test.rules.test.txt
index a6c61be774cc..e52adfd18ad8 100644
--- a/.buildkite/test.rules.test.txt
+++ b/.buildkite/test.rules.test.txt
@@ -35,6 +35,15 @@ python/setup.py: ml tune train serve workflow data python dashboard linux_wheels
 python/requirements/test-requirements.txt: ml tune train serve workflow data python dashboard linux_wheels macos_wheels java python_dependencies min_build
 python/_raylet.pyx: ml tune train data python dashboard linux_wheels macos_wheels java
 
+# === Raydepsets lock files ===
+# macos_depset lock is consumed by the mac smoke test, so it must emit macos_wheels.
+python/deplocks/ci/macos_depset_py3.10.lock: macos_wheels
+# Other deplock updates should NOT trigger the mac smoke test (no macos_wheels).
+python/deplocks/base_deps/ray_base_deps_py3.10.lock: ml tune train serve workflow data python dashboard linux_wheels java python_dependencies min_build
+python/deplocks/ci/data-base-ci_depset_py3.10.lock: ml tune train serve workflow data python dashboard linux_wheels java python_dependencies min_build
+# LLM deplocks still hit the earlier llm rule block.
+python/deplocks/llm/ray_py311_cpu.lock: llm
+
 # === Buildkite Configs ===
 
 .buildkite/ml.rayci.yml: ml train train_gpu tune
diff --git a/.buildkite/test.rules.txt b/.buildkite/test.rules.txt
index c0cf800710f8..302bdd69b81f 100644
--- a/.buildkite/test.rules.txt
+++ b/.buildkite/test.rules.txt
@@ -85,6 +85,24 @@ python/ray/dashboard/
 @ dashboard linux_wheels python
 ;
 
+# The macOS smoke test installs this specific lock file
+# (ci/ray_ci/macos/macos_ci.sh), so changes here must still trigger
+# macos_wheels. Must precede the general python/deplocks/ rule below.
+python/deplocks/ci/macos_depset_py*
+@ macos_wheels
+;
+
+# Raydepsets-generated lock files. These do NOT affect the macOS smoke
+# test (which only consumes macos_depset_py*, handled above), so we
+# deliberately omit macos_wheels here to avoid running mac tests on
+# unrelated lock updates. Otherwise mirrors the python/setup.py rule's
+# tag set so general dependency changes still fan out across CI.
+python/deplocks/
+@ ml tune train serve workflow data min_build
+@ python dashboard linux_wheels java
+@ python_dependencies
+;
+
 python/setup.py
 python/requirements.txt
 python/requirements_compiled.txt