diff --git a/extensions/panache/hibernate-orm-panache-common/runtime/src/main/java/io/quarkus/hibernate/orm/panache/common/runtime/AbstractJpaOperations.java b/extensions/panache/hibernate-orm-panache-common/runtime/src/main/java/io/quarkus/hibernate/orm/panache/common/runtime/AbstractJpaOperations.java
index 980a272a07d3b..83d4aca1ad8a9 100644
--- a/extensions/panache/hibernate-orm-panache-common/runtime/src/main/java/io/quarkus/hibernate/orm/panache/common/runtime/AbstractJpaOperations.java
+++ b/extensions/panache/hibernate-orm-panache-common/runtime/src/main/java/io/quarkus/hibernate/orm/panache/common/runtime/AbstractJpaOperations.java
@@ -20,7 +20,6 @@
 import org.hibernate.query.SelectionQuery;
 
 import io.agroal.api.AgroalDataSource;
-import io.quarkus.agroal.DataSource;
 import io.quarkus.arc.Arc;
 import io.quarkus.arc.ArcContainer;
 import io.quarkus.arc.InstanceHandle;
@@ -84,12 +83,6 @@ public Session getSession(String persistentUnitName) {
         if (sessionHandle.isAvailable()) {
             return sessionHandle.get();
         }
-        if (!arcContainer.instance(AgroalDataSource.class,
-                new DataSource.DataSourceLiteral(persistentUnitName)).isAvailable()) {
-            throw new IllegalStateException(
-                    "The named datasource '" + persistentUnitName
-                            + "' has not been properly configured. See https://quarkus.io/guides/datasource#multiple-datasources for information on how to do that.");
-        }
         throw new IllegalStateException(
                 "No entities were attached to persistence unit '" + persistentUnitName
                         + "'. Did you forget to annotate your Panache Entity classes with '@Entity' or improperly configure the 'quarkus.hibernate-orm.\" "