diff --git a/Lib/test/test_posix.py b/Lib/test/test_posix.py
index 11180b7278c9d7..55077354589df9 100644
--- a/Lib/test/test_posix.py
+++ b/Lib/test/test_posix.py
@@ -308,6 +308,14 @@ def test_preadv_flags(self):
             buf = [bytearray(i) for i in [5, 3, 2]]
             self.assertEqual(posix.preadv(fd, buf, 3, os.RWF_HIPRI), 10)
             self.assertEqual([b't1tt2', b't3t', b'5t'], list(buf))
+        except OSError as inst:
+            # Is possible that the macro RWF_HIPRI was defined at compilation time
+            # but the option is not supported by the kernel or the runtime libc shared
+            # library.
+            if inst.errno in {errno.EINVAL, errno.ENOTSUP}:
+                raise unittest.SkipTest("RWF_HIPRI is not supported by the current system")
+            else:
+                raise
         finally:
             os.close(fd)