diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index bc5b1e4d7c..5be824c1cb 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -29,11 +29,6 @@ jobs:
         - platform: ubuntu-latest
           python: "3.10"
           distutils: stdlib
-        exclude:
-        # The combination of PyPy+Windows+pytest-xdist+ProcessPoolExecutor is flaky/problematic
-        - platform: windows-2019
-          python: pypy-3.7
-          distutils: local
     runs-on: ${{ matrix.platform }}
     env:
       SETUPTOOLS_USE_DISTUTILS: ${{ matrix.distutils }}
diff --git a/setuptools/tests/test_build_meta.py b/setuptools/tests/test_build_meta.py
index eb43fe9b0e..c4cdda0306 100644
--- a/setuptools/tests/test_build_meta.py
+++ b/setuptools/tests/test_build_meta.py
@@ -18,6 +18,13 @@
 IS_PYPY = '__pypy__' in sys.builtin_module_names
 
 
+pytestmark = pytest.mark.skipif(
+    sys.platform == "win32" and IS_PYPY,
+    reason="The combination of PyPy + Windows + pytest-xdist + ProcessPoolExecutor "
+    "is flaky and problematic"
+)
+
+
 class BuildBackendBase:
     def __init__(self, cwd='.', env={}, backend_name='setuptools.build_meta'):
         self.cwd = cwd