diff --git a/ChangeLog b/ChangeLog
index 52007414b8..4427e1c393 100644
--- a/ChangeLog
+++ b/ChangeLog
@@ -63,6 +63,7 @@ Release date: TBA
   attribute to itself without any prior assignment.
 
   Closes #1555
+  Closes #6221
 
 * The concept of checker priority has been removed.
 
diff --git a/doc/whatsnew/2.14.rst b/doc/whatsnew/2.14.rst
index dfe548f4bd..01d635aa84 100644
--- a/doc/whatsnew/2.14.rst
+++ b/doc/whatsnew/2.14.rst
@@ -81,3 +81,4 @@ Other Changes
   attribute to itself without any prior assignment.
 
   Closes #1555
+  Closes #6221
diff --git a/pylint/checkers/typecheck.py b/pylint/checkers/typecheck.py
index 2ab5ced330..0d2c8f691a 100644
--- a/pylint/checkers/typecheck.py
+++ b/pylint/checkers/typecheck.py
@@ -1053,6 +1053,11 @@ def visit_attribute(self, node: nodes.Attribute) -> None:
                 missingattr.add((owner, name))
                 continue
             else:
+                if isinstance(attr_nodes, nodes.NodeNG):
+                    # If owner was a living object, attr_nodes might be a node itself
+                    # Faster than retrieving the module object and testing _is_c_extension()
+                    # https://github.com/PyCQA/pylint/pull/6235#issuecomment-1093098869
+                    break  # pragma: no cover
                 for attr_node in attr_nodes:
                     attr_parent = attr_node.parent
                     # Skip augmented assignments