diff --git a/crates/oxc_transformer/src/plugins/styled_components.rs b/crates/oxc_transformer/src/plugins/styled_components.rs
index bb76ac3cfb953..90bee5c40122e 100644
--- a/crates/oxc_transformer/src/plugins/styled_components.rs
+++ b/crates/oxc_transformer/src/plugins/styled_components.rs
@@ -1061,7 +1061,16 @@ fn minify_template_literal<'a>(lit: &mut TemplateLiteral<'a>, ast: AstBuilder<'a
                 }
                 // Skip and compress whitespace.
                 _ if cur_byte.is_ascii_whitespace() => {
-                    i += 1;
+                    // Consume any following whitespace
+                    let mut next_byte;
+                    loop {
+                        i += 1;
+                        next_byte = bytes.get(i);
+                        if next_byte.is_none_or(|&b| !b.is_ascii_whitespace()) {
+                            break;
+                        }
+                    }
+
                     // Decide whether to preserve this whitespace character.
                     // CSS allows removing spaces around certain delimiters without changing meaning:
                     // - `color: red` -> `color:red` (spaces around colons)
@@ -1085,7 +1094,7 @@ fn minify_template_literal<'a>(lit: &mut TemplateLiteral<'a>, ast: AstBuilder<'a
                     //   are significant in CSS. ` :hover` (descendant pseudo-selector) is different
                     //   from `:hover` (direct pseudo-selector). Example: `.parent :hover` selects any
                     //   hovered descendant, while `.parent:hover` selects the parent when hovered.
-                    && bytes.get(i).is_none_or(|&next| !matches!(next, b'{' | b'}' | b',' | b';'))
+                    && next_byte.is_none_or(|&next| !matches!(next, b'{' | b'}' | b',' | b';'))
                     {
                         // Preserve this space character.
                         // Examples:
diff --git a/tasks/transform_conformance/snapshots/oxc.snap.md b/tasks/transform_conformance/snapshots/oxc.snap.md
index 0eeec2fe5cb77..94c6c09a414d6 100644
--- a/tasks/transform_conformance/snapshots/oxc.snap.md
+++ b/tasks/transform_conformance/snapshots/oxc.snap.md
@@ -1,6 +1,6 @@
 commit: 41d96516
 
-Passed: 183/306
+Passed: 184/307
 
 # All Passed:
 * babel-plugin-transform-class-static-block
@@ -1612,7 +1612,7 @@ after transform: ["Function", "babelHelpers"]
 rebuilt        : ["babelHelpers", "dec"]
 
 
-# plugin-styled-components (21/36)
+# plugin-styled-components (22/37)
 * styled-components/add-identifier-with-top-level-import-paths/input.js
 x Output mismatch
 
diff --git a/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/input.js b/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/input.js
new file mode 100644
index 0000000000000..02652ca2f135b
--- /dev/null
+++ b/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/input.js
@@ -0,0 +1,13 @@
+import styled from 'styled-components';
+
+const A = styled.div`
+  .a { }
+  .b   {     }
+  .c
+  {
+  }
+`;
+
+const B = styled.div`
+  str: "x    y";
+`;
diff --git a/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/options.json b/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/options.json
new file mode 100644
index 0000000000000..92abfec80959e
--- /dev/null
+++ b/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/options.json
@@ -0,0 +1,18 @@
+{
+  "presets": [
+    [
+      "@babel/preset-env",
+      {
+        "modules": false,
+        "targets": "defaults"
+      }
+    ]
+  ],
+  "plugins": [
+    ["styled-components", {
+      "ssr": false,
+      "displayName": false,
+      "transpileTemplateLiterals": false
+    }]
+  ]
+}
diff --git a/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/output.js b/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/output.js
new file mode 100644
index 0000000000000..c1e786e1e242e
--- /dev/null
+++ b/tasks/transform_conformance/tests/plugin-styled-components/test/fixtures/minify-whitespace-repeated/output.js
@@ -0,0 +1,3 @@
+import styled from 'styled-components';
+const A = styled.div`.a{}.b{}.c{}`;
+const B = styled.div`str:"x    y";`;