diff --git a/.env.development b/.env.development
index 26bd22668..5ad65ae2f 100644
--- a/.env.development
+++ b/.env.development
@@ -23,3 +23,5 @@ LOGO_TRADEMARK_URL=https://edx-cdn.org/v3/default/logo-trademark.svg
 LOGO_WHITE_URL=https://edx-cdn.org/v3/default/logo-white.svg
 FAVICON_URL=https://edx-cdn.org/v3/default/favicon.ico
 IGNORED_ERROR_REGEX=
+MFE_CONFIG_API_URL=
+APP_ID=
diff --git a/.env.test b/.env.test
index 26bd22668..5ad65ae2f 100644
--- a/.env.test
+++ b/.env.test
@@ -23,3 +23,5 @@ LOGO_TRADEMARK_URL=https://edx-cdn.org/v3/default/logo-trademark.svg
 LOGO_WHITE_URL=https://edx-cdn.org/v3/default/logo-white.svg
 FAVICON_URL=https://edx-cdn.org/v3/default/favicon.ico
 IGNORED_ERROR_REGEX=
+MFE_CONFIG_API_URL=
+APP_ID=
diff --git a/example/index.jsx b/example/index.jsx
index ff5513e67..37e65b8f2 100644
--- a/example/index.jsx
+++ b/example/index.jsx
@@ -11,6 +11,7 @@ import {
 } from '@edx/frontend-platform/react';
 import { APP_INIT_ERROR, APP_READY, initialize } from '@edx/frontend-platform';
 import { subscribe } from '@edx/frontend-platform/pubSub';
+import { IntlProvider } from '@edx/frontend-platform/i18n';
 
 import './index.scss';
 import ExamplePage from './ExamplePage';
@@ -32,7 +33,7 @@ subscribe(APP_READY, () => {
 });
 
 subscribe(APP_INIT_ERROR, (error) => {
-  ReactDOM.render(<ErrorPage message={error.message} />, document.getElementById('root'));
+  ReactDOM.render(<IntlProvider><ErrorPage message={error.message} /></IntlProvider>, document.getElementById('root'));
 });
 
 initialize({
diff --git a/src/config.js b/src/config.js
index b6d3532a5..0f12bc41b 100644
--- a/src/config.js
+++ b/src/config.js
@@ -67,6 +67,8 @@ let config = {
   LOGO_TRADEMARK_URL: process.env.LOGO_TRADEMARK_URL,
   LOGO_WHITE_URL: process.env.LOGO_WHITE_URL,
   FAVICON_URL: process.env.FAVICON_URL,
+  MFE_CONFIG_API_URL: process.env.MFE_CONFIG_API_URL,
+  APP_ID: process.env.APP_ID,
 };
 
 /**
@@ -193,4 +195,6 @@ export function ensureConfig(keys, requester = 'unspecified application code') {
  * @property {string} LOGO_TRADEMARK_URL
  * @property {string} LOGO_WHITE_URL
  * @property {string} FAVICON_URL
+ * @property {string} MFE_CONFIG_API_URL
+ * @property {string} APP_ID
  */
diff --git a/src/initialize.js b/src/initialize.js
index 8312c9d6c..f27fe4d00 100644
--- a/src/initialize.js
+++ b/src/initialize.js
@@ -50,7 +50,9 @@ import {
   publish,
 } from './pubSub';
 // eslint-disable-next-line import/no-cycle
-import { getConfig } from './config';
+import {
+  getConfig, mergeConfig,
+} from './config';
 import {
   configure as configureLogging, getLoggingService, NewRelicLoggingService, logError,
 } from './logging';
@@ -76,6 +78,7 @@ import {
   APP_ANALYTICS_INITIALIZED,
   APP_READY, APP_INIT_ERROR,
 } from './constants';
+import configureCache from './auth/LocalForageCache';
 
 /**
  * A browser history or memory history object created by the [history](https://github.com/ReactTraining/history)
@@ -127,6 +130,32 @@ export async function auth(requireUser, hydrateUser) {
     hydrateAuthenticatedUser();
   }
 }
+/*
+ * Set or overrides configuration through an API.
+ * This method allows runtime configuration.
+ * Set a basic configuration when an error happen and allow initError and display the ErrorPage.
+ */
+
+export async function runtimeConfig() {
+  try {
+    const { MFE_CONFIG_API_URL, APP_ID } = getConfig();
+
+    if (MFE_CONFIG_API_URL) {
+      const apiConfig = { headers: { accept: 'application/json' } };
+      const apiService = await configureCache();
+
+      const params = new URLSearchParams();
+      params.append('mfe', APP_ID);
+      const url = `${MFE_CONFIG_API_URL}?${params.toString()}`;
+
+      const { data } = await apiService.get(url, apiConfig);
+      mergeConfig(data);
+    }
+  } catch (error) {
+    // eslint-disable-next-line no-console
+    console.error('Error with config API', error.message);
+  }
+}
 
 /**
  * The default handler for the initialization lifecycle's `analytics` phase.
@@ -224,6 +253,7 @@ export async function initialize({
 
     // Configuration
     await handlers.config();
+    await runtimeConfig();
     publish(APP_CONFIG_INITIALIZED);
 
     // Logging
diff --git a/src/initialize.test.js b/src/initialize.test.js
index 545b6e87c..70b4f1018 100644
--- a/src/initialize.test.js
+++ b/src/initialize.test.js
@@ -30,13 +30,51 @@ import {
 import { configure as configureAnalytics, SegmentAnalyticsService } from './analytics';
 import { configure as configureI18n } from './i18n';
 import { getConfig } from './config';
+import configureCache from './auth/LocalForageCache';
 
 jest.mock('./logging');
 jest.mock('./auth');
 jest.mock('./analytics');
 jest.mock('./i18n');
+jest.mock('./auth/LocalForageCache');
 
 let config = null;
+const newConfig = {
+  common: {
+    SITE_NAME: 'Test Case',
+    LOGO_URL: 'http://test.example.com:18000/theme/logo.png',
+    LOGO_TRADEMARK_URL: 'http://test.example.com:18000/theme/logo.png',
+    LOGO_WHITE_URL: 'http://test.example.com:18000/theme/logo.png',
+    ACCESS_TOKEN_COOKIE_NAME: 'edx-jwt-cookie-header-payload',
+    FAVICON_URL: 'http://test.example.com:18000/theme/favicon.ico',
+    CSRF_TOKEN_API_PATH: '/csrf/api/v1/token',
+    DISCOVERY_API_BASE_URL: 'http://test.example.com:18381',
+    PUBLISHER_BASE_URL: 'http://test.example.com:18400',
+    ECOMMERCE_BASE_URL: 'http://test.example.com:18130',
+    LANGUAGE_PREFERENCE_COOKIE_NAME: 'openedx-language-preference',
+    LEARNING_BASE_URL: 'http://test.example.com:2000',
+    LMS_BASE_URL: 'http://test.example.com:18000',
+    LOGIN_URL: 'http://test.example.com:18000/login',
+    LOGOUT_URL: 'http://test.example.com:18000/logout',
+    STUDIO_BASE_URL: 'http://studio.example.com:18010',
+    MARKETING_SITE_BASE_URL: 'http://test.example.com:18000',
+    ORDER_HISTORY_URL: 'http://test.example.com:1996/orders',
+    REFRESH_ACCESS_TOKEN_ENDPOINT: 'http://test.example.com:18000/login_refresh',
+    SEGMENT_KEY: '',
+    USER_INFO_COOKIE_NAME: 'edx-user-info',
+    IGNORED_ERROR_REGEX: '',
+    CREDENTIALS_BASE_URL: 'http://test.example.com:18150',
+  },
+  auth: {
+    INFO_EMAIL: 'openedx@example.com',
+    ACTIVATION_EMAIL_SUPPORT_LINK: 'http//support.test.com',
+  },
+  learning: {
+    LEGACY_THEME_NAME: 'example',
+    DISCUSSIONS_MFE_BASE_URL: 'http://test.example.com:2002',
+  },
+};
+
 describe('initialize', () => {
   beforeEach(() => {
     config = getConfig();
@@ -240,4 +278,81 @@ describe('initialize', () => {
     expect(overrideHandlers.ready).not.toHaveBeenCalled();
     expect(overrideHandlers.initError).toHaveBeenCalledWith(new Error('uhoh!'));
   });
+
+  it('should initialize the app with runtime configuration', async () => {
+    config.MFE_CONFIG_API_URL = 'http://localhost:18000/api/mfe/v1/config';
+    config.APP_ID = 'auth';
+    configureCache.mockReturnValueOnce(Promise.resolve({
+      get: (url) => {
+        const params = new URL(url).search;
+        const mfe = new URLSearchParams(params).get('mfe');
+        return ({ data: { ...newConfig.common, ...newConfig[mfe] } });
+      },
+    }));
+
+    const messages = { i_am: 'a message' };
+    await initialize({ messages });
+
+    expect(configureCache).toHaveBeenCalled();
+    expect(configureLogging).toHaveBeenCalledWith(NewRelicLoggingService, { config });
+    expect(configureAuth).toHaveBeenCalledWith(AxiosJwtAuthService, {
+      loggingService: getLoggingService(),
+      config,
+      middleware: [],
+    });
+    expect(configureAnalytics).toHaveBeenCalledWith(SegmentAnalyticsService, {
+      config,
+      loggingService: getLoggingService(),
+      httpClient: getAuthenticatedHttpClient(),
+    });
+    expect(configureI18n).toHaveBeenCalledWith({
+      messages,
+      config,
+      loggingService: getLoggingService(),
+    });
+
+    expect(fetchAuthenticatedUser).toHaveBeenCalled();
+    expect(ensureAuthenticatedUser).not.toHaveBeenCalled();
+    expect(hydrateAuthenticatedUser).not.toHaveBeenCalled();
+    expect(logError).not.toHaveBeenCalled();
+    expect(config.SITE_NAME).toBe(newConfig.common.SITE_NAME);
+    expect(config.INFO_EMAIL).toBe(newConfig.auth.INFO_EMAIL);
+    expect(Object.values(config).includes(newConfig.learning.DISCUSSIONS_MFE_BASE_URL)).toBeFalsy();
+  });
+
+  it('should initialize the app with the build config when runtime configuration fails', async () => {
+    config.MFE_CONFIG_API_URL = 'http://localhost:18000/api/mfe/v1/config';
+    // eslint-disable-next-line no-console
+    console.error = jest.fn();
+    configureCache.mockReturnValueOnce(Promise.reject(new Error('Api fails')));
+
+    const messages = { i_am: 'a message' };
+    await initialize({
+      messages,
+    });
+
+    expect(configureCache).toHaveBeenCalled();
+    // eslint-disable-next-line no-console
+    expect(console.error).toHaveBeenCalledWith('Error with config API', 'Api fails');
+    expect(configureLogging).toHaveBeenCalledWith(NewRelicLoggingService, { config });
+    expect(configureAuth).toHaveBeenCalledWith(AxiosJwtAuthService, {
+      loggingService: getLoggingService(),
+      config,
+      middleware: [],
+    });
+    expect(configureAnalytics).toHaveBeenCalledWith(SegmentAnalyticsService, {
+      config,
+      loggingService: getLoggingService(),
+      httpClient: getAuthenticatedHttpClient(),
+    });
+    expect(configureI18n).toHaveBeenCalledWith({
+      messages,
+      config,
+      loggingService: getLoggingService(),
+    });
+    expect(fetchAuthenticatedUser).toHaveBeenCalled();
+    expect(ensureAuthenticatedUser).not.toHaveBeenCalled();
+    expect(hydrateAuthenticatedUser).not.toHaveBeenCalled();
+    expect(logError).not.toHaveBeenCalled();
+  });
 });
diff --git a/src/setupTest.js b/src/setupTest.js
index 5bac1e543..310f306f2 100644
--- a/src/setupTest.js
+++ b/src/setupTest.js
@@ -32,6 +32,8 @@ process.env.LOGO_URL = 'https://edx-cdn.org/v3/default/logo.svg';
 process.env.LOGO_TRADEMARK_URL = 'https://edx-cdn.org/v3/default/logo-trademark.svg';
 process.env.LOGO_WHITE_URL = 'https://edx-cdn.org/v3/default/logo-white.svg';
 process.env.FAVICON_URL = 'https://edx-cdn.org/v3/default/favicon.ico';
+process.env.MFE_CONFIG_API_URL = '';
+process.env.APP_ID = '';
 
 /* Auth test variables