diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
index 7fa89d3603..2d4101648b 100644
--- a/.github/workflows/tests.yml
+++ b/.github/workflows/tests.yml
@@ -1,5 +1,5 @@
-# Do not edit this file by hand. This is generated automatically by running
-# generate_tests_yml.py.
+# Do not edit this file.
+# This file is generated automatically by executing generate_tests.py.
 
 name: Tests
 
@@ -211,24 +211,6 @@ jobs:
       - name: Run tests
         run: tox -e py312-test-exporter-prometheus-remote-write -- -ra
 
-  exporter-prometheus-remote-write_py3_ubuntu-latest:
-    name: exporter-prometheus-remote-write pypy-3.8 ubuntu
-    runs-on: ubuntu-latest
-    steps:
-      - name: Checkout Contrib Repo @ SHA - ${{ github.sha }}
-        uses: actions/checkout@v4
-
-      - name: Set up Python pypy-3.8
-        uses: actions/setup-python@v5
-        with:
-          python-version: "pypy-3.8"
-
-      - name: Install tox
-        run: pip install tox
-
-      - name: Run tests
-        run: tox -e pypy3-test-exporter-prometheus-remote-write -- -ra
-
   exporter-richconsole_38_ubuntu-latest:
     name: exporter-richconsole 3.8 ubuntu
     runs-on: ubuntu-latest
@@ -2047,24 +2029,6 @@ jobs:
       - name: Run tests
         run: tox -e py312-test-instrumentation-confluent-kafka -- -ra
 
-  instrumentation-confluent-kafka_py3_ubuntu-latest:
-    name: instrumentation-confluent-kafka pypy-3.8 ubuntu
-    runs-on: ubuntu-latest
-    steps:
-      - name: Checkout Contrib Repo @ SHA - ${{ github.sha }}
-        uses: actions/checkout@v4
-
-      - name: Set up Python pypy-3.8
-        uses: actions/setup-python@v5
-        with:
-          python-version: "pypy-3.8"
-
-      - name: Install tox
-        run: pip install tox
-
-      - name: Run tests
-        run: tox -e pypy3-test-instrumentation-confluent-kafka -- -ra
-
   instrumentation-dbapi_38_ubuntu-latest:
     name: instrumentation-dbapi 3.8 ubuntu
     runs-on: ubuntu-latest
@@ -3523,24 +3487,6 @@ jobs:
       - name: Run tests
         run: tox -e py312-test-instrumentation-grpc -- -ra
 
-  instrumentation-grpc_py3_ubuntu-latest:
-    name: instrumentation-grpc pypy-3.8 ubuntu
-    runs-on: ubuntu-latest
-    steps:
-      - name: Checkout Contrib Repo @ SHA - ${{ github.sha }}
-        uses: actions/checkout@v4
-
-      - name: Set up Python pypy-3.8
-        uses: actions/setup-python@v5
-        with:
-          python-version: "pypy-3.8"
-
-      - name: Install tox
-        run: pip install tox
-
-      - name: Run tests
-        run: tox -e pypy3-test-instrumentation-grpc -- -ra
-
   instrumentation-httpx_0_38_ubuntu-latest:
     name: instrumentation-httpx-0 3.8 ubuntu
     runs-on: ubuntu-latest
diff --git a/.github/workflows/tests.yml.j2 b/.github/workflows/tests.yml.j2
index 4739e7301f..d54992f74b 100644
--- a/.github/workflows/tests.yml.j2
+++ b/.github/workflows/tests.yml.j2
@@ -1,5 +1,5 @@
-# Do not edit this file by hand. This is generated automatically by running
-# generate_tests_yml.py.
+# Do not edit this file.
+# This file is generated automatically by executing generate_tests.py.
 
 name: Tests
 
diff --git a/tox.ini b/tox.ini
index 227a896c62..fadddc0af9 100644
--- a/tox.ini
+++ b/tox.ini
@@ -168,7 +168,6 @@ envlist =
 
     ; opentelemetry-exporter-prometheus-remote-write
     py3{8,9,10,11,12}-test-exporter-prometheus-remote-write
-    pypy3-test-exporter-prometheus-remote-write
     lint-exporter-prometheus-remote-write
 
     ; opentelemetry-instrumentation-mysql
@@ -243,7 +242,6 @@ envlist =
 
     ; opentelemetry-instrumentation-grpc
     py3{8,9,10,11,12}-test-instrumentation-grpc
-    pypy3-test-instrumentation-grpc
     lint-instrumentation-grpc
 
     ; opentelemetry-instrumentation-sqlalchemy
@@ -346,7 +344,6 @@ envlist =
 
     ; opentelemetry-instrumentation-confluent-kafka
     py3{8,9,10,11,12}-test-instrumentation-confluent-kafka
-    pypy3-test-instrumentation-confluent-kafka
     lint-instrumentation-confluent-kafka
 
     ; opentelemetry-instrumentation-asyncio