diff --git a/CHANGELOG.md b/CHANGELOG.md
index 3e8f981e0e..1aca02bbe9 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -13,6 +13,9 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - Fix exception in Urllib3 when dealing with filelike body.
   ([#1399](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/1399))
 
+- Add request and response hooks for GRPC instrumentation (client only)
+  ([#14](https://github.com/helios/opentelemetry-python-contrib/pull/14))
+
 ### Added
 
 - Add connection attributes to sqlalchemy connect span
diff --git a/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/__init__.py b/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/__init__.py
index 25010e147b..440d1facc8 100644
--- a/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/__init__.py
@@ -434,6 +434,8 @@ def __init__(self, filter_=None):
             else:
                 filter_ = any_of(filter_, excluded_service_filter)
         self._filter = filter_
+        self._request_hook = None
+        self._response_hook = None
 
     # Figures out which channel type we need to wrap
     def _which_channel(self, kwargs):
@@ -455,6 +457,8 @@ def instrumentation_dependencies(self) -> Collection[str]:
         return _instruments
 
     def _instrument(self, **kwargs):
+        self._request_hook = kwargs.get("request_hook")
+        self._response_hook = kwargs.get("response_hook")
         for ctype in self._which_channel(kwargs):
             _wrap(
                 "grpc",
@@ -469,11 +473,15 @@ def _uninstrument(self, **kwargs):
     def wrapper_fn(self, original_func, instance, args, kwargs):
         channel = original_func(*args, **kwargs)
         tracer_provider = kwargs.get("tracer_provider")
+        request_hook = self._request_hook
+        response_hook = self._response_hook
         return intercept_channel(
             channel,
             client_interceptor(
                 tracer_provider=tracer_provider,
                 filter_=self._filter,
+                request_hook=request_hook,
+                response_hook=response_hook,
             ),
         )
 
@@ -499,6 +507,8 @@ def __init__(self, filter_=None):
             else:
                 filter_ = any_of(filter_, excluded_service_filter)
         self._filter = filter_
+        self._request_hook = None
+        self._response_hook = None
 
     def instrumentation_dependencies(self) -> Collection[str]:
         return _instruments
@@ -507,13 +517,19 @@ def _add_interceptors(self, tracer_provider, kwargs):
         if "interceptors" in kwargs and kwargs["interceptors"]:
             kwargs["interceptors"] = (
                 aio_client_interceptors(
-                    tracer_provider=tracer_provider, filter_=self._filter
+                    tracer_provider=tracer_provider,
+                    filter_=self._filter,
+                    request_hook=self._request_hook,
+                    response_hook=self._response_hook,
                 )
                 + kwargs["interceptors"]
             )
         else:
             kwargs["interceptors"] = aio_client_interceptors(
-                tracer_provider=tracer_provider, filter_=self._filter
+                tracer_provider=tracer_provider,
+                filter_=self._filter,
+                request_hook=self._request_hook,
+                response_hook=self._response_hook,
             )
 
         return kwargs
@@ -521,6 +537,8 @@ def _add_interceptors(self, tracer_provider, kwargs):
     def _instrument(self, **kwargs):
         self._original_insecure = grpc.aio.insecure_channel
         self._original_secure = grpc.aio.secure_channel
+        self._request_hook = kwargs.get("request_hook")
+        self._response_hook = kwargs.get("response_hook")
         tracer_provider = kwargs.get("tracer_provider")
 
         def insecure(*args, **kwargs):
@@ -541,7 +559,9 @@ def _uninstrument(self, **kwargs):
         grpc.aio.secure_channel = self._original_secure
 
 
-def client_interceptor(tracer_provider=None, filter_=None):
+def client_interceptor(
+    tracer_provider=None, filter_=None, request_hook=None, response_hook=None
+):
     """Create a gRPC client channel interceptor.
 
     Args:
@@ -558,7 +578,12 @@ def client_interceptor(tracer_provider=None, filter_=None):
 
     tracer = trace.get_tracer(__name__, __version__, tracer_provider)
 
-    return _client.OpenTelemetryClientInterceptor(tracer, filter_=filter_)
+    return _client.OpenTelemetryClientInterceptor(
+        tracer,
+        filter_=filter_,
+        request_hook=request_hook,
+        response_hook=response_hook,
+    )
 
 
 def server_interceptor(tracer_provider=None, filter_=None):
@@ -581,7 +606,9 @@ def server_interceptor(tracer_provider=None, filter_=None):
     return _server.OpenTelemetryServerInterceptor(tracer, filter_=filter_)
 
 
-def aio_client_interceptors(tracer_provider=None, filter_=None):
+def aio_client_interceptors(
+    tracer_provider=None, filter_=None, request_hook=None, response_hook=None
+):
     """Create a gRPC client channel interceptor.
 
     Args:
@@ -595,10 +622,30 @@ def aio_client_interceptors(tracer_provider=None, filter_=None):
     tracer = trace.get_tracer(__name__, __version__, tracer_provider)
 
     return [
-        _aio_client.UnaryUnaryAioClientInterceptor(tracer, filter_=filter_),
-        _aio_client.UnaryStreamAioClientInterceptor(tracer, filter_=filter_),
-        _aio_client.StreamUnaryAioClientInterceptor(tracer, filter_=filter_),
-        _aio_client.StreamStreamAioClientInterceptor(tracer, filter_=filter_),
+        _aio_client.UnaryUnaryAioClientInterceptor(
+            tracer,
+            filter_=filter_,
+            request_hook=request_hook,
+            response_hook=response_hook,
+        ),
+        _aio_client.UnaryStreamAioClientInterceptor(
+            tracer,
+            filter_=filter_,
+            request_hook=request_hook,
+            response_hook=response_hook,
+        ),
+        _aio_client.StreamUnaryAioClientInterceptor(
+            tracer,
+            filter_=filter_,
+            request_hook=request_hook,
+            response_hook=response_hook,
+        ),
+        _aio_client.StreamStreamAioClientInterceptor(
+            tracer,
+            filter_=filter_,
+            request_hook=request_hook,
+            response_hook=response_hook,
+        ),
     ]
 
 
diff --git a/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_aio_client.py b/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_aio_client.py
index c7630bfe9f..5d5a5ccc46 100644
--- a/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_aio_client.py
+++ b/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_aio_client.py
@@ -13,6 +13,7 @@
 # limitations under the License.
 
 import functools
+import logging
 from collections import OrderedDict
 
 import grpc
@@ -28,8 +29,10 @@
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.trace.status import Status, StatusCode
 
+logger = logging.getLogger(__name__)
 
-def _unary_done_callback(span, code, details):
+
+def _unary_done_callback(span, code, details, response_hook):
     def callback(call):
         try:
             span.set_attribute(
@@ -43,6 +46,8 @@ def callback(call):
                         description=details,
                     )
                 )
+            response_hook(span, details)
+
         finally:
             span.end()
 
@@ -110,7 +115,11 @@ async def _wrap_unary_response(self, continuation, span):
             code = await call.code()
             details = await call.details()
 
-            call.add_done_callback(_unary_done_callback(span, code, details))
+            call.add_done_callback(
+                _unary_done_callback(
+                    span, code, details, self._call_response_hook
+                )
+            )
 
             return call
         except grpc.aio.AioRpcError as exc:
@@ -120,6 +129,8 @@ async def _wrap_unary_response(self, continuation, span):
     async def _wrap_stream_response(self, span, call):
         try:
             async for response in call:
+                if self._response_hook:
+                    self._call_response_hook(span, response)
                 yield response
         except Exception as exc:
             self.add_error_details_to_span(span, exc)
@@ -151,6 +162,9 @@ async def intercept_unary_unary(
         ) as span:
             new_details = self.propagate_trace_in_details(client_call_details)
 
+            if self._request_hook:
+                self._call_request_hook(span, request)
+
             continuation_with_args = functools.partial(
                 continuation, new_details, request
             )
@@ -175,7 +189,8 @@ async def intercept_unary_stream(
             new_details = self.propagate_trace_in_details(client_call_details)
 
             resp = await continuation(new_details, request)
-
+            if self._request_hook:
+                self._call_request_hook(span, request)
             return self._wrap_stream_response(span, resp)
 
 
diff --git a/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_client.py b/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_client.py
index 55a46d4a49..b966fff4db 100644
--- a/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_client.py
+++ b/instrumentation/opentelemetry-instrumentation-grpc/src/opentelemetry/instrumentation/grpc/_client.py
@@ -19,8 +19,9 @@
 
 """Implementation of the invocation-side open-telemetry interceptor."""
 
+import logging
 from collections import OrderedDict
-from typing import MutableMapping
+from typing import Callable, MutableMapping
 
 import grpc
 
@@ -33,6 +34,8 @@
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.trace.status import Status, StatusCode
 
+logger = logging.getLogger(__name__)
+
 
 class _CarrierSetter(Setter):
     """We use a custom setter in order to be able to lower case
@@ -59,12 +62,27 @@ def callback(response_future):
     return callback
 
 
+def _safe_invoke(function: Callable, *args):
+    function_name = "<unknown>"
+    try:
+        function_name = function.__name__
+        function(*args)
+    except Exception as ex:  # pylint:disable=broad-except
+        logger.error(
+            "Error when invoking function '%s'", function_name, exc_info=ex
+        )
+
+
 class OpenTelemetryClientInterceptor(
     grpcext.UnaryClientInterceptor, grpcext.StreamClientInterceptor
 ):
-    def __init__(self, tracer, filter_=None):
+    def __init__(
+        self, tracer, filter_=None, request_hook=None, response_hook=None
+    ):
         self._tracer = tracer
         self._filter = filter_
+        self._request_hook = request_hook
+        self._response_hook = response_hook
 
     def _start_span(self, method, **kwargs):
         service, meth = method.lstrip("/").split("/", 1)
@@ -99,6 +117,8 @@ def _trace_result(self, span, rpc_info, result):
         if isinstance(result, tuple):
             response = result[0]
         rpc_info.response = response
+        if self._response_hook:
+            self._call_response_hook(span, response)
         span.end()
         return result
 
@@ -127,7 +147,8 @@ def _intercept(self, request, metadata, client_info, invoker):
                     timeout=client_info.timeout,
                     request=request,
                 )
-
+                if self._request_hook:
+                    self._call_request_hook(span, request)
                 result = invoker(request, metadata)
             except Exception as exc:
                 if isinstance(exc, grpc.RpcError):
@@ -148,6 +169,16 @@ def _intercept(self, request, metadata, client_info, invoker):
                     span.end()
         return self._trace_result(span, rpc_info, result)
 
+    def _call_request_hook(self, span, request):
+        if not callable(self._request_hook):
+            return
+        _safe_invoke(self._request_hook, span, request)
+
+    def _call_response_hook(self, span, response):
+        if not callable(self._response_hook):
+            return
+        _safe_invoke(self._response_hook, span, response)
+
     def intercept_unary(self, request, metadata, client_info, invoker):
         if self._filter is not None and not self._filter(client_info):
             return invoker(request, metadata)
diff --git a/instrumentation/opentelemetry-instrumentation-grpc/tests/test_aio_client_interceptor_hooks.py b/instrumentation/opentelemetry-instrumentation-grpc/tests/test_aio_client_interceptor_hooks.py
new file mode 100644
index 0000000000..fe906b26c1
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-grpc/tests/test_aio_client_interceptor_hooks.py
@@ -0,0 +1,120 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+try:
+    from unittest import IsolatedAsyncioTestCase
+except ImportError:
+    # unittest.IsolatedAsyncioTestCase was introduced in Python 3.8. It's use
+    # simplifies the following tests. Without it, the amount of test code
+    # increases significantly, with most of the additional code handling
+    # the asyncio set up.
+    from unittest import TestCase
+
+    class IsolatedAsyncioTestCase(TestCase):
+        def run(self, result=None):
+            self.skipTest(
+                "This test requires Python 3.8 for unittest.IsolatedAsyncioTestCase"
+            )
+
+
+import grpc
+import pytest
+
+from opentelemetry.instrumentation.grpc import GrpcAioInstrumentorClient
+from opentelemetry.test.test_base import TestBase
+
+from ._aio_client import simple_method
+from ._server import create_test_server
+from .protobuf import test_server_pb2_grpc  # pylint: disable=no-name-in-module
+
+
+def request_hook(span, request):
+    span.set_attribute("request_data", request.request_data)
+
+
+def response_hook(span, response):
+    span.set_attribute("response_data", response)
+
+
+def request_hook_with_exception(_span, _request):
+    raise Exception()
+
+
+def response_hook_with_exception(_span, _response):
+    raise Exception()
+
+
+@pytest.mark.asyncio
+class TestAioClientInterceptorWithHooks(TestBase, IsolatedAsyncioTestCase):
+    def setUp(self):
+        super().setUp()
+        self.server = create_test_server(25565)
+        self.server.start()
+
+    def tearDown(self):
+        super().tearDown()
+        self.server.stop(None)
+
+    async def test_request_and_response_hooks(self):
+        instrumentor = GrpcAioInstrumentorClient()
+
+        try:
+            instrumentor.instrument(
+                request_hook=request_hook,
+                response_hook=response_hook,
+            )
+
+            channel = grpc.aio.insecure_channel(
+                "localhost:25565",
+            )
+            stub = test_server_pb2_grpc.GRPCTestServerStub(channel)
+
+            response = await simple_method(stub)
+            assert response.response_data == "data"
+
+            spans = self.memory_exporter.get_finished_spans()
+            self.assertEqual(len(spans), 1)
+            span = spans[0]
+
+            self.assertIn("request_data", span.attributes)
+            self.assertEqual(span.attributes["request_data"], "data")
+
+            self.assertIn("response_data", span.attributes)
+            self.assertEqual(span.attributes["response_data"], "")
+        finally:
+            instrumentor.uninstrument()
+
+    async def test_hooks_with_exception(self):
+        instrumentor = GrpcAioInstrumentorClient()
+
+        try:
+            instrumentor.instrument(
+                request_hook=request_hook_with_exception,
+                response_hook=response_hook_with_exception,
+            )
+
+            channel = grpc.aio.insecure_channel(
+                "localhost:25565",
+            )
+            stub = test_server_pb2_grpc.GRPCTestServerStub(channel)
+
+            response = await simple_method(stub)
+            assert response.response_data == "data"
+
+            spans = self.memory_exporter.get_finished_spans()
+            self.assertEqual(len(spans), 1)
+            span = spans[0]
+
+            self.assertEqual(span.name, "/GRPCTestServer/SimpleMethod")
+        finally:
+            instrumentor.uninstrument()
diff --git a/instrumentation/opentelemetry-instrumentation-grpc/tests/test_client_interceptor_hooks.py b/instrumentation/opentelemetry-instrumentation-grpc/tests/test_client_interceptor_hooks.py
new file mode 100644
index 0000000000..ca649f7bb1
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-grpc/tests/test_client_interceptor_hooks.py
@@ -0,0 +1,149 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+import grpc
+from tests.protobuf import (  # pylint: disable=no-name-in-module
+    test_server_pb2_grpc,
+)
+
+from opentelemetry import trace
+from opentelemetry.instrumentation.grpc import GrpcInstrumentorClient
+from opentelemetry.test.test_base import TestBase
+
+from ._client import simple_method
+from ._server import create_test_server
+
+
+# User defined interceptor. Is used in the tests along with the opentelemetry client interceptor.
+class Interceptor(
+    grpc.UnaryUnaryClientInterceptor,
+    grpc.UnaryStreamClientInterceptor,
+    grpc.StreamUnaryClientInterceptor,
+    grpc.StreamStreamClientInterceptor,
+):
+    def __init__(self):
+        pass
+
+    def intercept_unary_unary(
+        self, continuation, client_call_details, request
+    ):
+        return self._intercept_call(continuation, client_call_details, request)
+
+    def intercept_unary_stream(
+        self, continuation, client_call_details, request
+    ):
+        return self._intercept_call(continuation, client_call_details, request)
+
+    def intercept_stream_unary(
+        self, continuation, client_call_details, request_iterator
+    ):
+        return self._intercept_call(
+            continuation, client_call_details, request_iterator
+        )
+
+    def intercept_stream_stream(
+        self, continuation, client_call_details, request_iterator
+    ):
+        return self._intercept_call(
+            continuation, client_call_details, request_iterator
+        )
+
+    @staticmethod
+    def _intercept_call(
+        continuation, client_call_details, request_or_iterator
+    ):
+        return continuation(client_call_details, request_or_iterator)
+
+
+def request_hook(span, request):
+    span.set_attribute("request_data", request.request_data)
+
+
+def response_hook(span, response):
+    span.set_attribute("response_data", response.response_data)
+
+
+def request_hook_with_exception(_span, _request):
+    raise Exception()
+
+
+def response_hook_with_exception(_span, _response):
+    raise Exception()
+
+
+class TestHooks(TestBase):
+    def setUp(self):
+        super().setUp()
+        self.server = create_test_server(25565)
+        self.server.start()
+        # use a user defined interceptor along with the opentelemetry client interceptor
+        self.interceptors = [Interceptor()]
+
+    def tearDown(self):
+        super().tearDown()
+        self.server.stop(None)
+
+    def test_response_and_request_hooks(self):
+        instrumentor = GrpcInstrumentorClient()
+
+        try:
+            instrumentor.instrument(
+                request_hook=request_hook,
+                response_hook=response_hook,
+            )
+
+            channel = grpc.insecure_channel("localhost:25565")
+            channel = grpc.intercept_channel(channel, *self.interceptors)
+
+            stub = test_server_pb2_grpc.GRPCTestServerStub(channel)
+
+            simple_method(stub)
+            spans = self.memory_exporter.get_finished_spans()
+            self.assertEqual(len(spans), 1)
+            span = spans[0]
+
+            self.assertEqual(span.name, "/GRPCTestServer/SimpleMethod")
+            self.assertIs(span.kind, trace.SpanKind.CLIENT)
+
+            self.assertIn("request_data", span.attributes)
+            self.assertEqual(span.attributes["request_data"], "data")
+
+            self.assertIn("response_data", span.attributes)
+            self.assertEqual(span.attributes["response_data"], "data")
+        finally:
+            instrumentor.uninstrument()
+
+    def test_hooks_with_exception(self):
+        instrumentor = GrpcInstrumentorClient()
+
+        try:
+            instrumentor.instrument(
+                request_hook=request_hook_with_exception,
+                response_hook=response_hook_with_exception,
+            )
+
+            channel = grpc.insecure_channel("localhost:25565")
+            channel = grpc.intercept_channel(channel, *self.interceptors)
+
+            stub = test_server_pb2_grpc.GRPCTestServerStub(channel)
+
+            simple_method(stub)
+            spans = self.memory_exporter.get_finished_spans()
+            self.assertEqual(len(spans), 1)
+            span = spans[0]
+
+            self.assertEqual(span.name, "/GRPCTestServer/SimpleMethod")
+            self.assertIs(span.kind, trace.SpanKind.CLIENT)
+        finally:
+            instrumentor.uninstrument()