diff --git a/experimental/CHANGELOG.md b/experimental/CHANGELOG.md
index e81dec8e1d2..2449816bf7f 100644
--- a/experimental/CHANGELOG.md
+++ b/experimental/CHANGELOG.md
@@ -18,6 +18,8 @@ For notes on migrating to 2.x / 0.200.x see [the upgrade guide](doc/upgrade-to-2
 
 ### :house: Internal
 
+* test(otlp-grpc-exporter-base): increase timeout in flaky test [#6042](https://github.com/open-telemetry/opentelemetry-js/pull/6042) @cjihrig
+
 ## 0.207.0
 
 ### :boom: Breaking Changes
diff --git a/experimental/packages/otlp-grpc-exporter-base/test/grpc-exporter-transport.test.ts b/experimental/packages/otlp-grpc-exporter-base/test/grpc-exporter-transport.test.ts
index 3cc3f76eadd..3edc23cc2bd 100644
--- a/experimental/packages/otlp-grpc-exporter-base/test/grpc-exporter-transport.test.ts
+++ b/experimental/packages/otlp-grpc-exporter-base/test/grpc-exporter-transport.test.ts
@@ -71,7 +71,7 @@ const simpleClientConfig: GrpcExporterTransportParameters = {
   address: 'localhost:1234',
 };
 
-const timeoutMillis = 100;
+const timeoutMillis = 10_000;
 
 interface ExportedData {
   request: Buffer;