diff --git a/experimental/CHANGELOG.md b/experimental/CHANGELOG.md
index fbf8564590..1894e8f781 100644
--- a/experimental/CHANGELOG.md
+++ b/experimental/CHANGELOG.md
@@ -10,6 +10,8 @@ All notable changes to experimental packages in this project will be documented
 
 ### :bug: (Bug Fix)
 
+* fix(instrumentation): update `require-in-the-middle` to v7.0.1 [#3743](https://github.com/open-telemetry/opentelemetry-js/pull/3743) @trentm
+
 ### :books: (Refine Doc)
 
 ### :house: (Internal)
diff --git a/experimental/packages/opentelemetry-instrumentation/package.json b/experimental/packages/opentelemetry-instrumentation/package.json
index 7b50f5051b..04d913ae86 100644
--- a/experimental/packages/opentelemetry-instrumentation/package.json
+++ b/experimental/packages/opentelemetry-instrumentation/package.json
@@ -68,7 +68,7 @@
     "url": "https://github.com/open-telemetry/opentelemetry-js/issues"
   },
   "dependencies": {
-    "require-in-the-middle": "^6.0.0",
+    "require-in-the-middle": "^7.0.1",
     "semver": "^7.3.2",
     "shimmer": "^1.2.1"
   },