diff --git a/experimental/packages/opentelemetry-instrumentation-fetch/src/fetch.ts b/experimental/packages/opentelemetry-instrumentation-fetch/src/fetch.ts
index 1f762f429b..939da135f2 100644
--- a/experimental/packages/opentelemetry-instrumentation-fetch/src/fetch.ts
+++ b/experimental/packages/opentelemetry-instrumentation-fetch/src/fetch.ts
@@ -27,6 +27,7 @@ import { AttributeNames } from './enums/AttributeNames';
 import { SemanticAttributes } from '@opentelemetry/semantic-conventions';
 import { FetchError, FetchResponse, SpanData } from './types';
 import { VERSION } from './version';
+import { _globalThis } from '@opentelemetry/core';
 
 // how long to wait for observer to collect information about resources
 // this is needed as event "load" is called before observer
@@ -288,13 +289,14 @@ export class FetchInstrumentation extends InstrumentationBase<
   /**
    * Patches the constructor of fetch
    */
-  private _patchConstructor(): (original: Window['fetch']) => Window['fetch'] {
+  private _patchConstructor(): (original: typeof fetch) => typeof fetch {
     return original => {
       const plugin = this;
       return function patchConstructor(
-        this: Window,
-        ...args: Parameters<Window['fetch']>
+        this: typeof globalThis,
+        ...args: Parameters<typeof fetch>
       ): Promise<Response> {
+        const self = this;
         const url = args[0] instanceof Request ? args[0].url : args[0];
         const options = args[0] instanceof Request ? args[0] : args[1] || {};
         const createdSpan = plugin._createSpan(url, options);
@@ -377,11 +379,13 @@ export class FetchInstrumentation extends InstrumentationBase<
             () => {
               plugin._addHeaders(options, url);
               plugin._tasksCount++;
+              // TypeScript complains about arrow function captured a this typed as globalThis
+              // ts(7041)
               return original
-                .apply(this, options instanceof Request ? [options] : [url, options])
+                .apply(self, options instanceof Request ? [options] : [url, options])
                 .then(
-                  onSuccess.bind(this, createdSpan, resolve),
-                  onError.bind(this, createdSpan, reject)
+                  onSuccess.bind(self, createdSpan, resolve),
+                  onError.bind(self, createdSpan, reject)
                 );
             }
           );
@@ -420,18 +424,17 @@ export class FetchInstrumentation extends InstrumentationBase<
   private _prepareSpanData(spanUrl: string): SpanData {
     const startTime = core.hrTime();
     const entries: PerformanceResourceTiming[] = [];
-    if (typeof window.PerformanceObserver === 'undefined') {
+    if (PerformanceObserver == null) {
       return { entries, startTime, spanUrl };
     }
 
     const observer: PerformanceObserver = new PerformanceObserver(list => {
       const perfObsEntries = list.getEntries() as PerformanceResourceTiming[];
-      const urlNormalizingAnchor = web.getUrlNormalizingAnchor();
-      urlNormalizingAnchor.href = spanUrl;
+      const parsedUrl = web.parseUrl(spanUrl);
       perfObsEntries.forEach(entry => {
         if (
           entry.initiatorType === 'fetch' &&
-          entry.name === urlNormalizingAnchor.href
+          entry.name === parsedUrl.href
         ) {
           entries.push(entry);
         }
@@ -447,18 +450,18 @@ export class FetchInstrumentation extends InstrumentationBase<
    * implements enable function
    */
   override enable(): void {
-    if (isWrapped(window.fetch)) {
-      this._unwrap(window, 'fetch');
+    if (isWrapped(fetch)) {
+      this._unwrap(_globalThis, 'fetch');
       this._diag.debug('removing previous patch for constructor');
     }
-    this._wrap(window, 'fetch', this._patchConstructor());
+    this._wrap(_globalThis, 'fetch', this._patchConstructor());
   }
 
   /**
    * implements unpatch function
    */
   override disable(): void {
-    this._unwrap(window, 'fetch');
+    this._unwrap(_globalThis, 'fetch');
     this._usedResources = new WeakSet<PerformanceResourceTiming>();
   }
 }
diff --git a/experimental/packages/opentelemetry-instrumentation-xml-http-request/src/xhr.ts b/experimental/packages/opentelemetry-instrumentation-xml-http-request/src/xhr.ts
index 1d0c9faac1..dfadaed386 100644
--- a/experimental/packages/opentelemetry-instrumentation-xml-http-request/src/xhr.ts
+++ b/experimental/packages/opentelemetry-instrumentation-xml-http-request/src/xhr.ts
@@ -29,7 +29,6 @@ import {
   parseUrl,
   PerformanceTimingNames as PTN,
   shouldPropagateTraceHeaders,
-  getUrlNormalizingAnchor
 } from '@opentelemetry/sdk-trace-web';
 import { EventNames } from './enums/EventNames';
 import {
@@ -209,21 +208,20 @@ export class XMLHttpRequestInstrumentation extends InstrumentationBase<XMLHttpRe
     const xhrMem = this._xhrMem.get(xhr);
     if (
       !xhrMem ||
-      typeof window.PerformanceObserver === 'undefined' ||
-      typeof window.PerformanceResourceTiming === 'undefined'
+      PerformanceObserver == null ||
+      PerformanceResourceTiming == null
     ) {
       return;
     }
     xhrMem.createdResources = {
       observer: new PerformanceObserver(list => {
         const entries = list.getEntries() as PerformanceResourceTiming[];
-        const urlNormalizingAnchor = getUrlNormalizingAnchor();
-        urlNormalizingAnchor.href = spanUrl;
+        const parsedUrl = parseUrl(spanUrl);
 
         entries.forEach(entry => {
           if (
             entry.initiatorType === 'xmlhttprequest' &&
-            entry.name === urlNormalizingAnchor.href
+            entry.name === parsedUrl.href
           ) {
             if (xhrMem.createdResources) {
               xhrMem.createdResources.entries.push(entry);
diff --git a/packages/opentelemetry-exporter-zipkin/src/platform/browser/util.ts b/packages/opentelemetry-exporter-zipkin/src/platform/browser/util.ts
index 222f138d07..96008e4172 100644
--- a/packages/opentelemetry-exporter-zipkin/src/platform/browser/util.ts
+++ b/packages/opentelemetry-exporter-zipkin/src/platform/browser/util.ts
@@ -94,7 +94,7 @@ function sendWithXhr(
   urlStr: string,
   xhrHeaders: Record<string, string> = {}
 ) {
-  const xhr = new window.XMLHttpRequest();
+  const xhr = new XMLHttpRequest();
   xhr.open('POST', urlStr);
   Object.entries(xhrHeaders).forEach(([k, v]) => {
     xhr.setRequestHeader(k, v);
diff --git a/packages/opentelemetry-sdk-trace-web/src/utils.ts b/packages/opentelemetry-sdk-trace-web/src/utils.ts
index 829955feb0..58831f4f21 100644
--- a/packages/opentelemetry-sdk-trace-web/src/utils.ts
+++ b/packages/opentelemetry-sdk-trace-web/src/utils.ts
@@ -30,7 +30,7 @@ import { SemanticAttributes } from '@opentelemetry/semantic-conventions';
 
 // Used to normalize relative URLs
 let urlNormalizingAnchor: HTMLAnchorElement | undefined;
-export function getUrlNormalizingAnchor(): HTMLAnchorElement {
+function getUrlNormalizingAnchor(): HTMLAnchorElement {
   if (!urlNormalizingAnchor) {
     urlNormalizingAnchor = document.createElement('a');
   }
@@ -140,9 +140,8 @@ export function getResource(
   initiatorType?: string
 ): PerformanceResourceTimingInfo {
   // de-relativize the URL before usage (does no harm to absolute URLs)
-  const urlNormalizingAnchor = getUrlNormalizingAnchor();
-  urlNormalizingAnchor.href = spanUrl;
-  spanUrl = urlNormalizingAnchor.href;
+  const parsedSpanUrl = parseUrl(spanUrl);
+  spanUrl = parsedSpanUrl.toString();
 
   const filteredResources = filterResourcesForSpan(
     spanUrl,
@@ -165,7 +164,6 @@ export function getResource(
   }
   const sorted = sortResources(filteredResources);
 
-  const parsedSpanUrl = parseUrl(spanUrl);
   if (parsedSpanUrl.origin !== window.location.origin && sorted.length > 1) {
     let corsPreFlightRequest: PerformanceResourceTiming | undefined = sorted[0];
     let mainRequest: PerformanceResourceTiming = findMainRequest(
@@ -280,15 +278,48 @@ function filterResourcesForSpan(
 }
 
 /**
- * Parses url using anchor element
+ * The URLLike interface represents an URL and HTMLAnchorElement compatible fields.
+ */
+export interface URLLike {
+  hash: string;
+  host: string;
+  hostname: string;
+  href: string;
+  readonly origin: string;
+  password: string;
+  pathname: string;
+  port: string;
+  protocol: string;
+  search: string;
+  username: string;
+}
+
+/**
+ * Parses url using URL constructor or fallback to anchor element.
  * @param url
  */
-export function parseUrl(url: string): HTMLAnchorElement {
-  const element = document.createElement('a');
+export function parseUrl(url: string): URLLike {
+  if (typeof URL === 'function') {
+    return new URL(url);
+  }
+  const element = getUrlNormalizingAnchor();
   element.href = url;
   return element;
 }
 
+/**
+ * Parses url using URL constructor or fallback to anchor element and serialize
+ * it to a string.
+ *
+ * Performs the steps described in https://html.spec.whatwg.org/multipage/urls-and-fetching.html#parse-a-url
+ *
+ * @param url
+ */
+export function normalizeUrl(url: string): string {
+  const urlLike = parseUrl(url);
+  return urlLike.href;
+}
+
 /**
  * Get element XPath
  * @param target - target element
diff --git a/packages/opentelemetry-sdk-trace-web/test/utils.test.ts b/packages/opentelemetry-sdk-trace-web/test/utils.test.ts
index 085c621352..b8217e4f13 100644
--- a/packages/opentelemetry-sdk-trace-web/test/utils.test.ts
+++ b/packages/opentelemetry-sdk-trace-web/test/utils.test.ts
@@ -29,8 +29,11 @@ import {
   addSpanNetworkEvents,
   getElementXPath,
   getResource,
+  normalizeUrl,
+  parseUrl,
   PerformanceEntries,
   shouldPropagateTraceHeaders,
+  URLLike,
 } from '../src';
 import { PerformanceTimingNames as PTN } from '../src/enums/PerformanceTimingNames';
 
@@ -587,6 +590,49 @@ describe('utils', () => {
       assert.strictEqual(result, false);
     });
   });
+
+  describe('parseUrl', () => {
+    const urlFields: Array<keyof URLLike> = [
+      'hash',
+      'host',
+      'hostname',
+      'href',
+      'origin',
+      'password',
+      'pathname',
+      'port',
+      'protocol',
+      'search',
+      'username',
+    ];
+    it('should parse url', () => {
+      const url = parseUrl('https://opentelemetry.io/foo');
+      urlFields.forEach(field => {
+        assert.strictEqual(typeof url[field], 'string');
+      });
+    });
+
+    it('should parse url with fallback', () => {
+      sinon.stub(window, 'URL').value(undefined);
+      const url = parseUrl('https://opentelemetry.io/foo');
+      urlFields.forEach(field => {
+        assert.strictEqual(typeof url[field], 'string');
+      });
+    });
+  });
+
+  describe('normalizeUrl', () => {
+    it('should normalize url', () => {
+      const url = normalizeUrl('https://opentelemetry.io/你好');
+      assert.strictEqual(url, 'https://opentelemetry.io/%E4%BD%A0%E5%A5%BD');
+    });
+
+    it('should parse url with fallback', () => {
+      sinon.stub(window, 'URL').value(undefined);
+      const url = normalizeUrl('https://opentelemetry.io/你好');
+      assert.strictEqual(url, 'https://opentelemetry.io/%E4%BD%A0%E5%A5%BD');
+    });
+  });
 });
 
 function getElementByXpath(path: string) {