diff --git a/CHANGELOG.md b/CHANGELOG.md
index adcd71b5f7..d93d3c6661 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -37,6 +37,7 @@ OpenTelemetry Go Automatic Instrumentation adheres to [Semantic Versioning](http
 - Cache offsets for `go.opentelemetry.io/otel` `v1.40.0`. ([#3268](https://github.com/open-telemetry/opentelemetry-go-instrumentation/pull/3268))
 - Cache offsets for Go `1.24.13`. ([#3280](https://github.com/open-telemetry/opentelemetry-go-instrumentation/pull/3280))
 - Cache offsets for Go `1.25.7`. ([#3280](https://github.com/open-telemetry/opentelemetry-go-instrumentation/pull/3280))
+- Cache offsets for `golang.org/x/net` `0.50.0`. ([#3297](https://github.com/open-telemetry/opentelemetry-go-instrumentation/pull/3297))
 
 ### Removed
 
diff --git a/internal/pkg/inject/offset_results.json b/internal/pkg/inject/offset_results.json
index 6a8cf21e9c..10fa3fc428 100644
--- a/internal/pkg/inject/offset_results.json
+++ b/internal/pkg/inject/offset_results.json
@@ -1689,7 +1689,8 @@
                       "0.46.0",
                       "0.47.0",
                       "0.48.0",
-                      "0.49.0"
+                      "0.49.0",
+                      "0.50.0"
                     ]
                   }
                 ]
@@ -1753,7 +1754,8 @@
                       "0.46.0",
                       "0.47.0",
                       "0.48.0",
-                      "0.49.0"
+                      "0.49.0",
+                      "0.50.0"
                     ]
                   }
                 ]