diff --git a/docs/execution_providers/QNN-ExecutionProvider.md b/docs/execution_providers/QNN-ExecutionProvider.md
index 82f334605c..bf0798e499 100644
--- a/docs/execution_providers/QNN-ExecutionProvider.md
+++ b/docs/execution_providers/QNN-ExecutionProvider.md
@@ -37,7 +37,7 @@ download the Qualcomm AI Runtime SDK (QAIRT SDK) from [https://qpm.qualcomm.com/
 ONNX Runtime QNN EP has been built and tested with the following SDK version combinations on Windows:
 | QNN EP Version | QAIRT SDK Version | ONNX Runtime Version |
 |----------------|-------------------|----------------------|
-| v2.0.0         | v2.42.0           | v1.24.1              |
+| v2.0.0         | v2.45.0           | v1.24.4              |
 
 > **Note**: ONNX Runtime QNN EP is built and tested by using the arm64 ONNX Runtime SDK (ex: onnxruntime-win-arm64-1.24.0.zip).
 
diff --git a/onnxruntime/core/providers/qnn/builder/qnn_backend_manager.cc b/onnxruntime/core/providers/qnn/builder/qnn_backend_manager.cc
index 20471418da..05eb9b7016 100644
--- a/onnxruntime/core/providers/qnn/builder/qnn_backend_manager.cc
+++ b/onnxruntime/core/providers/qnn/builder/qnn_backend_manager.cc
@@ -1760,10 +1760,13 @@ Ort::Status QnnBackendManager::SetupBackend(
   if (share_ep_contexts && !load_from_cached_context) {
 #if (defined(__aarch64__) || defined(_M_ARM64)) && \
     (QNN_API_VERSION_MAJOR < 2 || (QNN_API_VERSION_MAJOR == 2 && QNN_API_VERSION_MINOR < 34))
-    ORT_CXX_LOG_PTR(logger_ptr_, ORT_LOGGING_LEVEL_WARNING, ("FINDME: " + std::to_string(QNN_API_VERSION_MAJOR) + "." + std::to_string(QNN_API_VERSION_MINOR) + "." + std::to_string(QNN_API_VERSION_PATCH)).c_str());
     ORT_CXX_LOG_PTR(logger_ptr_,
                     ORT_LOGGING_LEVEL_WARNING,
                     "Weight sharing on Windows arm64 device requires QNN API version >=2.34. Since Current version is too old, disabling the Weight sharing.");
+#elif defined(__ANDROID__)
+    ORT_CXX_LOG_PTR(logger_ptr_,
+                    ORT_LOGGING_LEVEL_WARNING,
+                    "Weight sharing on Android devices is disabled");
 #else
     enable_htp_weight_sharing = true;
 #endif
diff --git a/onnxruntime/test/providers/qnn/qnn_device_compatibility_test.cc b/onnxruntime/test/providers/qnn/qnn_device_compatibility_test.cc
index 9f73d705c8..2869b95367 100644
--- a/onnxruntime/test/providers/qnn/qnn_device_compatibility_test.cc
+++ b/onnxruntime/test/providers/qnn/qnn_device_compatibility_test.cc
@@ -144,9 +144,16 @@ TEST_F(QnnDeviceCompatibilityTests, GPUDeviceWithQualcommVendorIsCompatible) {
       env_, onnxruntime::kQnnExecutionProvider, &gpu_device, &details));
   ASSERT_NE(details, nullptr);
 
-  // Verify compatible (no incompatibility reasons)
-  uint32_t reasons_bitmask = 0xFFFFFFFF;
+  // Check if GPU device is incompatible for any reason - if so, skip this test
+  uint32_t reasons_bitmask = 0;
   ASSERT_ORTSTATUS_OK(api_->DeviceEpIncompatibilityDetails_GetReasonsBitmask(details, &reasons_bitmask));
+
+  if (reasons_bitmask != 0u) {
+    api_->ReleaseDeviceEpIncompatibilityDetails(details);
+    GTEST_SKIP() << "GPU device is not compatible with QNN EP on this machine, skipping compatibility test";
+  }
+
+  // Verify compatible (no incompatibility reasons)
   EXPECT_EQ(reasons_bitmask, 0u) << "GPU device with Qualcomm vendor should be compatible with QNN EP";
 
   int32_t error_code = -1;
@@ -349,6 +356,13 @@ TEST_F(QnnDeviceCompatibilityTests, GPUDeviceIncompatibilityDetailsWithMissingDe
     GTEST_SKIP() << "GPU device is compatible with QNN EP, skipping incompatibility test";
   }
 
+  if ((reasons_bitmask & OrtDeviceEpIncompatibility_MISSING_DEPENDENCY) == 0) {
+    // The GPU library is present but incompatible for another reason (e.g., driver failure).
+    // This test requires the GPU library itself to be absent; skip if that's not the case.
+    api_->ReleaseDeviceEpIncompatibilityDetails(details);
+    GTEST_SKIP() << "GPU library is present; MISSING_DEPENDENCY scenario cannot be reproduced";
+  }
+
   // Verify incompatibility reason includes MISSING_DEPENDENCY
   EXPECT_TRUE((reasons_bitmask & OrtDeviceEpIncompatibility_MISSING_DEPENDENCY) != 0)
       << "Expected MISSING_DEPENDENCY flag in incompatibility reasons";
diff --git a/onnxruntime/test/providers/qnn/qnn_ep_context_test.cc b/onnxruntime/test/providers/qnn/qnn_ep_context_test.cc
index 38e6d4bbb8..094a589cd5 100644
--- a/onnxruntime/test/providers/qnn/qnn_ep_context_test.cc
+++ b/onnxruntime/test/providers/qnn/qnn_ep_context_test.cc
@@ -2159,6 +2159,8 @@ TEST_F(QnnHTPBackendTests, QnnContextShareAcrossSessions) {
 #if (defined(__aarch64__) || defined(_M_ARM64)) && \
     !(QNN_API_VERSION_MAJOR > 2 || (QNN_API_VERSION_MAJOR == 2 && QNN_API_VERSION_MINOR >= 34))
   GTEST_SKIP() << "HTP weight sharing on ARM64 requires QNN API version >= 2.34.";
+#elif defined(__ANDROID__)
+  GTEST_SKIP() << "Weight sharing on Android devices is disabled";
 #endif
   ProviderOptions provider_options;
   provider_options["backend_type"] = "htp";
@@ -2270,6 +2272,13 @@ TEST_F(QnnHTPBackendTests, QnnContextShareAcrossSessions) {
 }
 
 TEST_F(QnnHTPBackendTests, DISABLED_VTCMBackupBufferSharing) {
+#if (defined(__aarch64__) || defined(_M_ARM64)) && \
+    !(QNN_API_VERSION_MAJOR > 2 || (QNN_API_VERSION_MAJOR == 2 && QNN_API_VERSION_MINOR >= 34))
+  GTEST_SKIP() << "HTP weight sharing on ARM64 requires QNN API version >= 2.34.";
+#elif defined(__ANDROID__)
+  GTEST_SKIP() << "Weight sharing on Android devices is disabled";
+#endif
+
   // Disable the test on test-android job in Qualcomm CI here while we investigate
   // but do not upstream this change.
   ProviderOptions provider_options;
@@ -2381,6 +2390,13 @@ TEST_F(QnnHTPBackendTests, DISABLED_VTCMBackupBufferSharing) {
 }
 
 TEST_F(QnnHTPBackendTests, FileMapping_Off) {
+#if (defined(__aarch64__) || defined(_M_ARM64)) && \
+    !(QNN_API_VERSION_MAJOR > 2 || (QNN_API_VERSION_MAJOR == 2 && QNN_API_VERSION_MINOR >= 34))
+  GTEST_SKIP() << "HTP weight sharing on ARM64 requires QNN API version >= 2.34.";
+#elif defined(__ANDROID__)
+  GTEST_SKIP() << "Weight sharing on Android devices is disabled";
+#endif
+
   ProviderOptions provider_options;
   provider_options["backend_type"] = "htp";
   provider_options["offload_graph_io_quantization"] = "0";
@@ -2502,6 +2518,8 @@ TEST_F(QnnHTPBackendTests, QnnContextGenWeightSharingSessionAPI) {
 #if (defined(__aarch64__) || defined(_M_ARM64)) && \
     !(QNN_API_VERSION_MAJOR > 2 || (QNN_API_VERSION_MAJOR == 2 && QNN_API_VERSION_MINOR >= 34))
   GTEST_SKIP() << "HTP weight sharing on ARM64 requires QNN API version >= 2.34.";
+#elif defined(__ANDROID__)
+  GTEST_SKIP() << "Weight sharing on Android devices is disabled";
 #endif
   ProviderOptions provider_options;
   provider_options["backend_type"] = "htp";
diff --git a/qcom/packages.yml b/qcom/packages.yml
index f8977ba5c7..f7344c3450 100644
--- a/qcom/packages.yml
+++ b/qcom/packages.yml
@@ -94,9 +94,9 @@ java_windows_x86_64:
   content_root: jdk-{version}
   bindir: bin
 model_zoo:
-  version: 2026-01-13
+  version: 2026-04-03
   url: http://ort-ep-win-01.na.qualcomm.com:8000/model-zoo/model-zoo-{version}.zip
-  sha256: 32853861b80c1ba913591a870dad2d1626ddb1683ac4750b65b1f0148ec9c7a7
+  sha256: 3a870c41c7b1aa8e8e2d7f2fd6dcc6c47de73da57ca3dc26b4f37d436c05a29e
   content_root: model-zoo
 ninja_linux_aarch64:
   version: 1.12.1
@@ -177,7 +177,7 @@ python_314_windows_arm64:
   version: 3.14.3
   md5: 1183951d055ef6c0ae1fb686b3342a6f
 qairt:
-  version: 2.44.0.260225
+  version: 2.45.0.260326
   url: https://softwarecenter.qualcomm.com/api/download/software/sdks/Qualcomm_AI_Runtime_Community/All/{version}/v{version}.zip
   content_root: qairt/{version}
   bindir: bin