diff --git a/source/NVDAObjects/__init__.py b/source/NVDAObjects/__init__.py
index 729a68cd353..e2a454380c3 100644
--- a/source/NVDAObjects/__init__.py
+++ b/source/NVDAObjects/__init__.py
@@ -1098,7 +1098,7 @@ def _get_basicText(self):
 		newTime=time.time()
 		oldTime=getattr(self,'_basicTextTime',0)
 		if newTime-oldTime>0.5:
-			self._basicText=u" ".join([x for x in self.name, self.value, self.description if isinstance(x, basestring) and len(x) > 0 and not x.isspace()])
+			self._basicText=u" ".join(x for x in (self.name, self.value, self.description) if isinstance(x, basestring) and len(x) > 0 and not x.isspace())
 			if len(self._basicText)==0:
 				self._basicText=u""
 		else:
diff --git a/source/appModules/soffice.py b/source/appModules/soffice.py
index 4aa10c775ae..478a84c2ddc 100755
--- a/source/appModules/soffice.py
+++ b/source/appModules/soffice.py
@@ -220,7 +220,7 @@ def _get_states(self):
 			# #8988: Cells in Libre Office do not have the selected state when a single cell is selected (i.e. has focus).
 			# Since #8898, the negative selected state is announced for table cells with the selectable state.
 			states.add(controlTypes.STATE_SELECTED)
- 		if self.IA2Attributes.get('Formula'):
+		if self.IA2Attributes.get('Formula'):
 			# #860: Recent versions of Calc expose has formula state via IAccessible 2.
 			states.add(controlTypes.STATE_HASFORMULA)
 		return states
diff --git a/source/baseObject.py b/source/baseObject.py
index 3b338f73742..865ff75cd17 100755
--- a/source/baseObject.py
+++ b/source/baseObject.py
@@ -69,7 +69,7 @@ def __init__(self,name,bases,dict):
 			s=dict.get('_set_%s'%x,None)
 			d=dict.get('_del_%s'%x,None)
 			if x in dict:
-				methodsString=",".join([str(i) for i in g,s,d if i])
+				methodsString=",".join(str(i) for i in (g,s,d) if i)
 				raise TypeError("%s is already a class attribute, cannot create descriptor with methods %s"%(x,methodsString))
 			if not g:
 				# There's a setter or deleter, but no getter.
diff --git a/source/characterProcessing.py b/source/characterProcessing.py
index b10d21d2572..6a55f61dc8d 100644
--- a/source/characterProcessing.py
+++ b/source/characterProcessing.py
@@ -509,7 +509,7 @@ def __init__(self, locale):
 		# Simple symbols.
 		# These are all handled in one named group.
 		# Because the symbols are just text, we know which symbol matched just by looking at the matched text.
-		patterns.append(ur"(?P<simple>{multiChars}|{singleChars})".format(
+		patterns.append(r"(?P<simple>{multiChars}|{singleChars})".format(
 			multiChars="|".join(re.escape(identifier) for identifier in multiChars),
 			singleChars=characters
 		))
diff --git a/source/config/__init__.py b/source/config/__init__.py
index d8431c20db7..2b74e16c28f 100644
--- a/source/config/__init__.py
+++ b/source/config/__init__.py
@@ -76,7 +76,7 @@ def saveOnExit():
 def isInstalledCopy():
 	"""Checks to see if this running copy of NVDA is installed on the system"""
 	try:
-		k=winreg.OpenKey(winreg.HKEY_LOCAL_MACHINE,"SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\NVDA")
+		k=winreg.OpenKey(winreg.HKEY_LOCAL_MACHINE,r"SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\NVDA")
 		instDir=winreg.QueryValueEx(k,"UninstallDirectory")[0]
 	except WindowsError:
 		return False
@@ -166,7 +166,7 @@ def initConfigPath(configPath=None):
 		if not os.path.isdir(subdir):
 			os.makedirs(subdir)
 
-RUN_REGKEY = ur"SOFTWARE\Microsoft\Windows\CurrentVersion\Run"
+RUN_REGKEY = r"SOFTWARE\Microsoft\Windows\CurrentVersion\Run"
 
 def getStartAfterLogon():
 	if (easeOfAccess.isSupported and easeOfAccess.canConfigTerminateOnDesktopSwitch
@@ -234,7 +234,7 @@ def execElevated(path, params=None, wait=False,handleAlreadyElevated=False):
 
 #: The name of the registry key stored under  HKEY_LOCAL_MACHINE where system wide NVDA settings are stored.
 #: Note that NVDA is a 32-bit application, so on X64 systems, this will evaluate to "SOFTWARE\WOW6432Node\nvda"
-NVDA_REGKEY = ur"SOFTWARE\NVDA"
+NVDA_REGKEY = r"SOFTWARE\NVDA"
 
 def getStartOnLogonScreen():
 	if easeOfAccess.isSupported and easeOfAccess.willAutoStart(winreg.HKEY_LOCAL_MACHINE):
diff --git a/source/hwPortUtils.py b/source/hwPortUtils.py
index f2c5e5f1769..6c70c8097f0 100644
--- a/source/hwPortUtils.py
+++ b/source/hwPortUtils.py
@@ -104,7 +104,7 @@ class dummy(ctypes.Structure):
 CR_SUCCESS = 0
 MAX_DEVICE_ID_LEN = 200
 
-GUID_CLASS_COMPORT = GUID(0x86e0d1e0L, 0x8089, 0x11d0,
+GUID_CLASS_COMPORT = GUID(0x86e0d1e0, 0x8089, 0x11d0,
 	(ctypes.c_ubyte*8)(0x9c, 0xe4, 0x08, 0x00, 0x3e, 0x30, 0x1f, 0x73))
 GUID_DEVINTERFACE_USB_DEVICE = GUID(0xA5DCBF10, 0x6530, 0x11D2,
 	(0x90, 0x1F, 0x00, 0xC0, 0x4F, 0xB9, 0x51, 0xED))
diff --git a/source/installer.py b/source/installer.py
index 31741c6959c..cd53ddb85b6 100644
--- a/source/installer.py
+++ b/source/installer.py
@@ -74,7 +74,7 @@ def getStartMenuFolder(noDefault=False):
 
 def getInstallPath(noDefault=False):
 	try:
-		k=winreg.OpenKey(winreg.HKEY_LOCAL_MACHINE,"SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\NVDA")
+		k=winreg.OpenKey(winreg.HKEY_LOCAL_MACHINE,r"SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\NVDA")
 		return winreg.QueryValueEx(k,"UninstallDirectory")[0]
 	except WindowsError:
 		return defaultInstallPath if not noDefault else None
diff --git a/source/locationHelper.py b/source/locationHelper.py
index 92575c50765..7f76bc61f49 100644
--- a/source/locationHelper.py
+++ b/source/locationHelper.py
@@ -6,7 +6,8 @@
 
 """Classes and helper functions for working with rectangles and coordinates."""
 
-from collections import namedtuple, Sequence
+from collections import namedtuple
+from collections.abc import Sequence
 import windowUtils
 import winUser
 from ctypes.wintypes import RECT, POINT, DWORD
diff --git a/source/logHandler.py b/source/logHandler.py
index b9384f1caa0..15f5e15cefe 100755
--- a/source/logHandler.py
+++ b/source/logHandler.py
@@ -93,7 +93,7 @@ def getCodePath(f):
 						className=cls.__name__
 				if className:
 					break
-	return ".".join([x for x in path,className,funcName if x])
+	return ".".join(x for x in (path,className,funcName) if x)
 
 # Function to strip the base path of our code from traceback text to improve readability.
 BASE_PATH = os.path.split(__file__)[0] + os.sep
diff --git a/source/mathPres/mathPlayer.py b/source/mathPres/mathPlayer.py
index e21627a4dd8..7b297f0520a 100644
--- a/source/mathPres/mathPlayer.py
+++ b/source/mathPres/mathPlayer.py
@@ -21,9 +21,9 @@
 	# Break.
 	r"<break time='(?P<break>\d+)ms'/> ?"
 	# Pronunciation of characters.
-	ur"|<say-as interpret-as='characters'>(?P<char>[^<])</say-as> ?"
+	r"|<say-as interpret-as='characters'>(?P<char>[^<])</say-as> ?"
 	# Specific pronunciation.
-	ur"|<phoneme alphabet='ipa' ph='(?P<ipa>[^']+)'> (?P<phonemeText>[^ <]+)</phoneme> ?"
+	r"|<phoneme alphabet='ipa' ph='(?P<ipa>[^']+)'> (?P<phonemeText>[^ <]+)</phoneme> ?"
 	# Prosody.
 	r"|<prosody(?: pitch='(?P<pitch>\d+)%')?(?: volume='(?P<volume>\d+)%')?(?: rate='(?P<rate>\d+)%')?> ?"
 	r"|(?P<prosodyReset></prosody>) ?"
diff --git a/source/nvda.pyw b/source/nvda.pyw
index 6fd8b66c7f2..538bfc5ccbc 100755
--- a/source/nvda.pyw
+++ b/source/nvda.pyw
@@ -179,7 +179,7 @@ isSecureDesktop = desktopName == "Winlogon"
 if isSecureDesktop:
 	import winreg
 	try:
-		k = winreg.OpenKey(winreg.HKEY_LOCAL_MACHINE, ur"SOFTWARE\NVDA")
+		k = winreg.OpenKey(winreg.HKEY_LOCAL_MACHINE, r"SOFTWARE\NVDA")
 		if not winreg.QueryValueEx(k, u"serviceDebug")[0]:
 			globalVars.appArgs.secure = True
 	except WindowsError:
diff --git a/source/setup.py b/source/setup.py
index ed11c4c88b4..a1108d985eb 100755
--- a/source/setup.py
+++ b/source/setup.py
@@ -190,7 +190,19 @@ def getRecursiveDataFiles(dest,source,excludes=()):
 	options = {"py2exe": {
 		"bundle_files": 3,
 		"excludes": ["tkinter",
-			"serial.loopback_connection", "serial.rfc2217", "serial.serialcli", "serial.serialjava", "serial.serialposix", "serial.socket_connection"],
+			"serial.loopback_connection", 
+			"serial.rfc2217", 
+			"serial.serialcli", 
+			"serial.serialjava", 
+			"serial.serialposix", 
+			"serial.socket_connection",
+			# netbios (from pywin32) is optionally used by Python3's uuid module.
+			# This is not needed.
+			"netbios",
+			# winxptheme is optionally used by wx.lib.agw.aui.
+			# We don't need this.
+			"winxptheme",
+			],
 		"packages": ["NVDAObjects","virtualBuffers","appModules","comInterfaces","brailleDisplayDrivers","synthDrivers"],
 		"includes": [
 			"nvdaBuiltin",
diff --git a/source/speech/__init__.py b/source/speech/__init__.py
index 6493809cd68..b3162c54cc1 100755
--- a/source/speech/__init__.py
+++ b/source/speech/__init__.py
@@ -1736,7 +1736,7 @@ def getTableInfoSpeech(tableInfo,oldTableInfo,extraDetail=False):
 		textList.append(_("row %s")%rowNumber)
 	return " ".join(textList)
 
-re_last_pause=re.compile(ur"^(.*(?<=[^\s.!?])[.!?][\"'”’)]?(?:\s+|$))(.*$)",re.DOTALL|re.UNICODE)
+re_last_pause=re.compile(r"^(.*(?<=[^\s.!?])[.!?][\"'”’)]?(?:\s+|$))(.*$)",re.DOTALL|re.UNICODE)
 
 def speakWithoutPauses(speechSequence,detectBreaks=True):
 	"""
diff --git a/source/virtualBuffers/__init__.py b/source/virtualBuffers/__init__.py
index 195110a9eca..2e39ccb6264 100644
--- a/source/virtualBuffers/__init__.py
+++ b/source/virtualBuffers/__init__.py
@@ -50,8 +50,8 @@ class VBufStorage_findMatch_word(unicode):
 
 FINDBYATTRIBS_ESCAPE_TABLE = {
 	# Symbols that are escaped in the attributes string.
-	ord(u":"): ur"\\:",
-	ord(u";"): ur"\\;",
+	ord(u":"): r"\\:",
+	ord(u";"): r"\\;",
 	ord(u"\\"): u"\\\\\\\\",
 }
 # Symbols that must be escaped for a regular expression.
diff --git a/source/watchdog.py b/source/watchdog.py
index 9c80c90b19a..b554799cf8e 100644
--- a/source/watchdog.py
+++ b/source/watchdog.py
@@ -291,7 +291,11 @@ def execute(self, func, args, kwargs, pumpMessages=True):
 
 		exc = self._exc_info
 		if exc:
-			raise exc[0], exc[1], exc[2]
+			# The execution of the function in the other thread caused an exception.
+			# Re-raise it here.
+			# Note that in Python3, the traceback (stack) is now part of the exception,
+			# So the logged traceback will correctly show the stack for both this thread and the other thread. 
+			raise exc
 		return self._result
 
 	def run(self):
@@ -301,8 +305,8 @@ def run(self):
 			self._executeEvent.clear()
 			try:
 				self._result = self._func(*self._args, **self._kwargs)
-			except:
-				self._exc_info = sys.exc_info()
+			except Exception as e:
+				self._exc_info = e
 			ctypes.windll.kernel32.SetEvent(self._executionDoneEvent)
 		ctypes.windll.kernel32.CloseHandle(self._executionDoneEvent)
 
diff --git a/source/winKernel.py b/source/winKernel.py
index 5484fbe5aba..b1e4b95cb4a 100644
--- a/source/winKernel.py
+++ b/source/winKernel.py
@@ -38,10 +38,10 @@
 DATE_LONGDATE=0x00000002 
 TIME_NOSECONDS=0x00000002
 # Wait return types
-WAIT_ABANDONED = 0x00000080L
-WAIT_IO_COMPLETION = 0x000000c0L
-WAIT_OBJECT_0 = 0x00000000L
-WAIT_TIMEOUT = 0x00000102L
+WAIT_ABANDONED = 0x00000080
+WAIT_IO_COMPLETION = 0x000000c0
+WAIT_OBJECT_0 = 0x00000000
+WAIT_TIMEOUT = 0x00000102
 WAIT_FAILED = 0xffffffff
 # Image file machine constants
 IMAGE_FILE_MACHINE_UNKNOWN = 0