diff --git a/lib/internal/util/comparisons.js b/lib/internal/util/comparisons.js
index 1145bc7d9971ba..679b80470190fc 100644
--- a/lib/internal/util/comparisons.js
+++ b/lib/internal/util/comparisons.js
@@ -80,6 +80,12 @@ function strictDeepEqual(val1, val2, memos) {
   if (Object.getPrototypeOf(val1) !== Object.getPrototypeOf(val2)) {
     return false;
   }
+  if (val1Tag === '[object WeakMap]' || val1Tag === '[object WeakSet]') {
+    // Note: Weak Reference Collection is not designed to check the equivalence.
+    // They are depends on Garbage Collection implementation.
+    // see: https://tc39.github.io/ecma262/#sec-weakmap-objects
+    return false;
+  }
   if (val1Tag === '[object Array]') {
     // Check for sparse arrays and general fast path
     if (val1.length !== val2.length)
diff --git a/test/parallel/test-util-isDeepStrictEqual.js b/test/parallel/test-util-isDeepStrictEqual.js
index 356a9a71324971..354c43b5ae4b59 100644
--- a/test/parallel/test-util-isDeepStrictEqual.js
+++ b/test/parallel/test-util-isDeepStrictEqual.js
@@ -481,3 +481,22 @@ utilIsDeepStrict(-0, -0);
   boxedStringA[symbol1] = true;
   utilIsDeepStrict(a, b);
 }
+
+// Handle WeakMap and WeakSet
+{
+  const wm1 = new WeakMap();
+  const wm2 = new WeakMap();
+  const key = {};
+  wm1.set(key, 1);
+  wm2.set(key, 1);
+  // seems to be equal but WeakMap is always false
+  notUtilIsDeepStrict(wm1, wm2);
+
+  const ws1 = new WeakSet();
+  const ws2 = new WeakSet();
+  const obj = {};
+  ws1.add(obj);
+  ws2.add(obj);
+  // seems to be equal but WeakSet is always false
+  notUtilIsDeepStrict(ws1, ws2);
+}