diff --git a/src/interceptors/ClientRequest/MockHttpSocket.ts b/src/interceptors/ClientRequest/MockHttpSocket.ts
index 35a60d30..be8f674b 100644
--- a/src/interceptors/ClientRequest/MockHttpSocket.ts
+++ b/src/interceptors/ClientRequest/MockHttpSocket.ts
@@ -126,6 +126,10 @@ export class MockHttpSocket extends MockSocket {
    * its data/events through this Socket.
    */
   public passthrough(): void {
+    if (this.destroyed) {
+      return
+    }
+
     const socket = this.createConnection()
     this.address = socket.address.bind(socket)
 
@@ -225,6 +229,12 @@ export class MockHttpSocket extends MockSocket {
    * HTTP message and push it to the socket.
    */
   public async respondWith(response: Response): Promise<void> {
+    // Ignore the mocked response if the socket has been destroyed
+    // (e.g. aborted or timed out),
+    if (this.destroyed) {
+      return
+    }
+
     // Handle "type: error" responses.
     if (isPropertyAccessible(response, 'type') && response.type === 'error') {
       this.errorWith(new TypeError('Network error'))
@@ -326,7 +336,7 @@ export class MockHttpSocket extends MockSocket {
   }
 
   /**
-   * Close this Socket connection with the given error.
+   * Close this socket connection with the given error.
    */
   public errorWith(error: Error): void {
     this.destroy(error)
diff --git a/test/modules/http/compliance/http-timeout.test.ts b/test/modules/http/compliance/http-timeout.test.ts
new file mode 100644
index 00000000..e23397e0
--- /dev/null
+++ b/test/modules/http/compliance/http-timeout.test.ts
@@ -0,0 +1,262 @@
+/**
+ * @vitest-environment node
+ */
+import { vi, it, expect, beforeAll, afterEach, afterAll } from 'vitest'
+import http from 'node:http'
+import { HttpServer } from '@open-draft/test-server/http'
+import { DeferredPromise } from '@open-draft/deferred-promise'
+import { ClientRequestInterceptor } from '../../../../src/interceptors/ClientRequest'
+import { sleep } from '../../../helpers'
+
+const httpServer = new HttpServer((app) => {
+  app.get('/resource', async (req, res) => {
+    await sleep(200)
+    res.status(500).end()
+  })
+})
+
+const interceptor = new ClientRequestInterceptor()
+
+beforeAll(async () => {
+  interceptor.apply()
+  await httpServer.listen()
+})
+
+afterEach(() => {
+  interceptor.removeAllListeners()
+})
+
+afterAll(async () => {
+  interceptor.dispose()
+  await httpServer.close()
+})
+
+it('respects the "timeout" option for a handled request', async () => {
+  interceptor.on('request', async ({ request }) => {
+    await sleep(200)
+    request.respondWith(new Response('hello world'))
+  })
+
+  const errorListener = vi.fn()
+  const timeoutListener = vi.fn()
+  const responseListener = vi.fn()
+  const request = http.get('http://localhost/resource', {
+    timeout: 10,
+  })
+  request.on('error', errorListener)
+  request.on('timeout', () => {
+    timeoutListener()
+    // Request must be destroyed manually on timeout.
+    request.destroy()
+  })
+  request.on('response', responseListener)
+
+  const requestClosePromise = new DeferredPromise<void>()
+  request.on('close', () => requestClosePromise.resolve())
+  await requestClosePromise
+
+  expect(request.destroyed).toBe(true)
+  expect(timeoutListener).toHaveBeenCalledTimes(1)
+  expect(errorListener).toHaveBeenCalledWith(
+    expect.objectContaining({
+      code: 'ECONNRESET',
+    })
+  )
+  expect(responseListener).not.toHaveBeenCalled()
+})
+
+it('respects the "timeout" option for a bypassed request', async () => {
+  const errorListener = vi.fn()
+  const timeoutListener = vi.fn()
+  const responseListener = vi.fn()
+  const request = http.get(httpServer.http.url('/resource'), {
+    timeout: 10,
+  })
+  request.on('error', errorListener)
+  request.on('timeout', () => {
+    timeoutListener()
+    // Request must be destroyed manually on timeout.
+    request.destroy()
+  })
+  request.on('response', responseListener)
+
+  const requestClosePromise = new DeferredPromise<void>()
+  request.on('close', () => requestClosePromise.resolve())
+  await requestClosePromise
+
+  expect(request.destroyed).toBe(true)
+  expect(timeoutListener).toHaveBeenCalledTimes(1)
+  expect(errorListener).toHaveBeenCalledWith(
+    expect.objectContaining({
+      code: 'ECONNRESET',
+    })
+  )
+  expect(responseListener).not.toHaveBeenCalled()
+})
+
+it('respects a "setTimeout()" on a handled request', async () => {
+  interceptor.on('request', async ({ request }) => {
+    const stream = new ReadableStream({
+      async start(controller) {
+        // Emulate a long pending response stream
+        // to trigger the request timeout.
+        await sleep(200)
+        controller.enqueue(new TextEncoder().encode('hello'))
+      },
+    })
+    request.respondWith(new Response(stream))
+  })
+
+  const errorListener = vi.fn()
+  const timeoutListener = vi.fn()
+  const setTimeoutCallback = vi.fn()
+  const responseListener = vi.fn()
+  const request = http.get('http://localhost/resource')
+
+  /**
+   * @note `request.setTimeout(n)` is NOT equivalent to
+   * `{ timeout: n }` in request options.
+   *
+   * - { timeout: n } acts on the http.Agent level and
+   * sets the timeout on every socket once it's CREATED.
+   *
+   * - setTimeout(n) omits the http.Agent, and sets the
+   * timeout once the socket emits "connect".
+   * This timeout takes effect only after the connection,
+   * so in our case, the mock/bypassed response MUST start,
+   * and only if the response itself takes more than this timeout,
+   * the timeout will trigger.
+   */
+  request.setTimeout(10, setTimeoutCallback)
+
+  request.on('error', errorListener)
+  request.on('timeout', () => {
+    timeoutListener()
+    request.destroy()
+  })
+  request.on('response', responseListener)
+
+  const requestClosePromise = new DeferredPromise<void>()
+  request.on('close', () => requestClosePromise.resolve())
+  await requestClosePromise
+
+  expect(request.destroyed).toBe(true)
+  expect(timeoutListener).toHaveBeenCalledTimes(1)
+  expect(setTimeoutCallback).toHaveBeenCalledTimes(1)
+  expect(errorListener).toHaveBeenCalledWith(
+    expect.objectContaining({
+      code: 'ECONNRESET',
+    })
+  )
+  expect(responseListener).not.toHaveBeenCalled()
+})
+
+it('respects a "setTimeout()" on a bypassed request', async () => {
+  const errorListener = vi.fn()
+  const timeoutListener = vi.fn()
+  const responseListener = vi.fn()
+  const request = http.get(httpServer.http.url('/resource'))
+  request.setTimeout(10)
+
+  request.on('error', errorListener)
+  request.on('timeout', () => {
+    timeoutListener()
+    request.destroy()
+  })
+  request.on('response', responseListener)
+
+  const requestClosePromise = new DeferredPromise<void>()
+  request.on('close', () => requestClosePromise.resolve())
+  await requestClosePromise
+
+  expect(request.destroyed).toBe(true)
+  expect(timeoutListener).toHaveBeenCalledTimes(1)
+  expect(errorListener).toHaveBeenCalledWith(
+    expect.objectContaining({
+      code: 'ECONNRESET',
+    })
+  )
+  expect(responseListener).not.toHaveBeenCalled()
+})
+
+it('respects the "socket.setTimeout()" for a handled request', async () => {
+  interceptor.on('request', async ({ request }) => {
+    const stream = new ReadableStream({
+      async start(controller) {
+        // Emulate a long pending response stream
+        // to trigger the request timeout.
+        await sleep(200)
+        controller.enqueue(new TextEncoder().encode('hello'))
+      },
+    })
+    request.respondWith(new Response(stream))
+  })
+
+  const errorListener = vi.fn()
+  const setTimeoutCallback = vi.fn()
+  const responseListener = vi.fn()
+  const request = http.get('http://localhost/resource')
+
+  request.on('socket', (socket) => {
+    /**
+     * @note Setting timeout on the socket directly
+     * will NOT add the "timeout" listener to the request,
+     * unlike "request.setTimeout()".
+     */
+    socket.setTimeout(10, () => {
+      setTimeoutCallback()
+      request.destroy()
+    })
+  })
+
+  request.on('error', errorListener)
+  request.on('response', responseListener)
+
+  const requestClosePromise = new DeferredPromise<void>()
+  request.on('close', () => requestClosePromise.resolve())
+  await requestClosePromise
+
+  expect(request.destroyed).toBe(true)
+  expect(setTimeoutCallback).toHaveBeenCalledTimes(1)
+  expect(errorListener).toHaveBeenCalledWith(
+    expect.objectContaining({
+      code: 'ECONNRESET',
+    })
+  )
+  expect(responseListener).not.toHaveBeenCalled()
+})
+
+it('respects the "socket.setTimeout()" for a bypassed request', async () => {
+  const errorListener = vi.fn()
+  const setTimeoutCallback = vi.fn()
+  const responseListener = vi.fn()
+  const request = http.get(httpServer.http.url('/resource'))
+
+  request.on('socket', (socket) => {
+    /**
+     * @note Setting timeout on the socket directly
+     * will NOT add the "timeout" listener to the request,
+     * unlike "request.setTimeout()".
+     */
+    socket.setTimeout(10, () => {
+      setTimeoutCallback()
+      request.destroy()
+    })
+  })
+
+  request.on('error', errorListener)
+  request.on('response', responseListener)
+
+  const requestClosePromise = new DeferredPromise<void>()
+  request.on('close', () => requestClosePromise.resolve())
+  await requestClosePromise
+
+  expect(request.destroyed).toBe(true)
+  expect(setTimeoutCallback).toHaveBeenCalledTimes(1)
+  expect(errorListener).toHaveBeenCalledWith(
+    expect.objectContaining({
+      code: 'ECONNRESET',
+    })
+  )
+  expect(responseListener).not.toHaveBeenCalled()
+})