diff --git a/ports/x264/portfile.cmake b/ports/x264/portfile.cmake
index 33e6979ac0e776..91264d443d37c1 100644
--- a/ports/x264/portfile.cmake
+++ b/ports/x264/portfile.cmake
@@ -29,7 +29,23 @@ if(VCPKG_TARGET_IS_UWP)
 endif()
 
 if(VCPKG_TARGET_IS_LINUX)
+
     list(APPEND OPTIONS --enable-pic)
+
+    if (VCPKG_TARGET_ARCHITECTURE STREQUAL "arm64")
+
+        vcpkg_cmake_get_vars(cmake_vars_file)
+        include("${cmake_vars_file}")
+
+        if (VCPKG_DETECTED_CMAKE_CROSSCOMPILING)
+            # Attempt to determine the fully qualified prefix from VCPKG_DETECTED_CMAKE_C_COMPILER (using most common naming conventions for linux targets)
+            # and if valid, use it to initialize --cross-prefix build-option of x264 package.
+            if(VCPKG_DETECTED_CMAKE_C_COMPILER MATCHES "^(.*-)gcc\$")
+                list(APPEND OPTIONS "--cross-prefix=${CMAKE_MATCH_1}")
+            endif()
+        endif()
+    endif()
+
 endif()
 
 vcpkg_configure_make(
@@ -45,7 +61,6 @@ vcpkg_configure_make(
         --disable-gpac
         --disable-lsmash
         --enable-debug
-
 )
 
 vcpkg_install_make()
diff --git a/ports/x264/vcpkg.json b/ports/x264/vcpkg.json
index 436cf0b5efd276..f863b23582734b 100644
--- a/ports/x264/vcpkg.json
+++ b/ports/x264/vcpkg.json
@@ -1,14 +1,19 @@
 {
   "name": "x264",
-  "version-string": "164-5db6aa6cab1b146",
-  "port-version": 4,
+  "version": "164-5db6aa6cab1b146",
+  "port-version": 5,
   "description": "x264 is a free software library and application for encoding video streams into the H.264/MPEG-4 AVC compression format",
   "homepage": "https://github.com/mirror/x264",
+  "license": "GPL-2.0-or-later",
   "supports": "!(arm & windows)",
   "dependencies": [
     {
       "name": "pthread",
       "platform": "linux & osx"
+    },
+    {
+      "name": "vcpkg-cmake",
+      "host": true
     }
   ]
 }
diff --git a/versions/baseline.json b/versions/baseline.json
index c6782a4d05506f..63fcaa25e70d91 100644
--- a/versions/baseline.json
+++ b/versions/baseline.json
@@ -7438,7 +7438,7 @@
     },
     "x264": {
       "baseline": "164-5db6aa6cab1b146",
-      "port-version": 4
+      "port-version": 5
     },
     "x265": {
       "baseline": "3.4",
diff --git a/versions/x-/x264.json b/versions/x-/x264.json
index bd8a969ea8dad4..7e0436eaa58f76 100644
--- a/versions/x-/x264.json
+++ b/versions/x-/x264.json
@@ -1,5 +1,10 @@
 {
   "versions": [
+    {
+      "git-tree": "c41df96f5b563f5ca75a965b0efc19f1daf05671",
+      "version": "164-5db6aa6cab1b146",
+      "port-version": 5
+    },
     {
       "git-tree": "7eea109502309e62a578bcc69811ad0659e00f9d",
       "version-string": "164-5db6aa6cab1b146",