diff --git a/tools/ci_build/github/azure-pipelines/android-arm64-v8a-QNN-crosscompile-ci-pipeline.yml b/tools/ci_build/github/azure-pipelines/android-arm64-v8a-QNN-crosscompile-ci-pipeline.yml
index 18a14aa0ac075..ba6a33b07e765 100644
--- a/tools/ci_build/github/azure-pipelines/android-arm64-v8a-QNN-crosscompile-ci-pipeline.yml
+++ b/tools/ci_build/github/azure-pipelines/android-arm64-v8a-QNN-crosscompile-ci-pipeline.yml
@@ -32,7 +32,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 jobs:
 - job: Build_QNN_EP
diff --git a/tools/ci_build/github/azure-pipelines/c-api-noopenmp-packaging-pipelines.yml b/tools/ci_build/github/azure-pipelines/c-api-noopenmp-packaging-pipelines.yml
index 8f1189b05858c..5313af8e7e2d5 100644
--- a/tools/ci_build/github/azure-pipelines/c-api-noopenmp-packaging-pipelines.yml
+++ b/tools/ci_build/github/azure-pipelines/c-api-noopenmp-packaging-pipelines.yml
@@ -57,7 +57,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK Version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 resources:
   repositories:
diff --git a/tools/ci_build/github/azure-pipelines/custom-nuget-packaging-pipeline.yml b/tools/ci_build/github/azure-pipelines/custom-nuget-packaging-pipeline.yml
index a6ad823594917..7b214dbdfae3a 100644
--- a/tools/ci_build/github/azure-pipelines/custom-nuget-packaging-pipeline.yml
+++ b/tools/ci_build/github/azure-pipelines/custom-nuget-packaging-pipeline.yml
@@ -6,7 +6,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK Version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 - name: IsReleaseBuild
   displayName: Is a release build? Set it to true if you are doing an Onnx Runtime release.
diff --git a/tools/ci_build/github/azure-pipelines/linux-qnn-ci-pipeline.yml b/tools/ci_build/github/azure-pipelines/linux-qnn-ci-pipeline.yml
index 704860587459a..f08fd70d6d6cf 100644
--- a/tools/ci_build/github/azure-pipelines/linux-qnn-ci-pipeline.yml
+++ b/tools/ci_build/github/azure-pipelines/linux-qnn-ci-pipeline.yml
@@ -33,7 +33,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 jobs:
   - job: Build_QNN_EP
diff --git a/tools/ci_build/github/azure-pipelines/py-packaging-pipeline.yml b/tools/ci_build/github/azure-pipelines/py-packaging-pipeline.yml
index 41549287cd3ab..d19f9bde7ad75 100644
--- a/tools/ci_build/github/azure-pipelines/py-packaging-pipeline.yml
+++ b/tools/ci_build/github/azure-pipelines/py-packaging-pipeline.yml
@@ -59,7 +59,7 @@ parameters:
 - name: qnn_sdk_version
   type: string
   displayName: 'QNN SDK version. Only for QNN packages.'
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 trigger: none
 
diff --git a/tools/ci_build/github/azure-pipelines/qnn-ep-nuget-packaging-pipeline.yml b/tools/ci_build/github/azure-pipelines/qnn-ep-nuget-packaging-pipeline.yml
index fedabba9083e6..34fbe74260ace 100644
--- a/tools/ci_build/github/azure-pipelines/qnn-ep-nuget-packaging-pipeline.yml
+++ b/tools/ci_build/github/azure-pipelines/qnn-ep-nuget-packaging-pipeline.yml
@@ -2,7 +2,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK Version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 - name: build_config
   displayName: Build Configuration
diff --git a/tools/ci_build/github/azure-pipelines/stages/py-cpu-packaging-stage.yml b/tools/ci_build/github/azure-pipelines/stages/py-cpu-packaging-stage.yml
index f5e827e277b40..4c18fb73cd779 100644
--- a/tools/ci_build/github/azure-pipelines/stages/py-cpu-packaging-stage.yml
+++ b/tools/ci_build/github/azure-pipelines/stages/py-cpu-packaging-stage.yml
@@ -59,7 +59,7 @@ parameters:
 - name: qnn_sdk_version
   type: string
   displayName: 'QNN SDK version. Only for QNN packages.'
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 stages:
 - ${{ if eq(parameters.enable_windows_cpu, true) }}:
diff --git a/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar-test.yml b/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar-test.yml
index 1d35c9461768d..da6263cc56975 100644
--- a/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar-test.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar-test.yml
@@ -17,7 +17,7 @@ parameters:
 - name: QnnSDKVersion
   displayName: QNN SDK Version
   type: string
-  default: '2.32.0.250228'
+  default: '2.33.2.250410'
 
 - name: enableWebGpu
   displayName: Enable WebGPU test
diff --git a/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar.yml b/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar.yml
index f930101f34d05..03839f8ac6282 100644
--- a/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/android-java-api-aar.yml
@@ -51,7 +51,7 @@ parameters:
 - name: QnnSDKVersion
   displayName: QNN SDK Version
   type: string
-  default: '2.32.0.250228'
+  default: '2.33.2.250410'
 
 - name: is1ES
   displayName: Is 1ES pipeline
diff --git a/tools/ci_build/github/azure-pipelines/templates/c-api-cpu.yml b/tools/ci_build/github/azure-pipelines/templates/c-api-cpu.yml
index 9b1d7b705e741..dd33777b2c20f 100644
--- a/tools/ci_build/github/azure-pipelines/templates/c-api-cpu.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/c-api-cpu.yml
@@ -45,7 +45,7 @@ parameters:
 - name: QnnSDKVersion
   displayName: QNN SDK Version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 - name: is1ES
   displayName: Is 1ES pipeline
diff --git a/tools/ci_build/github/azure-pipelines/templates/jobs/download_linux_qnn_sdk.yml b/tools/ci_build/github/azure-pipelines/templates/jobs/download_linux_qnn_sdk.yml
index 9ab308c440e21..e00e40b80b723 100644
--- a/tools/ci_build/github/azure-pipelines/templates/jobs/download_linux_qnn_sdk.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/jobs/download_linux_qnn_sdk.yml
@@ -1,7 +1,7 @@
 parameters:
   - name: QnnSDKVersion
     type: string
-    default: '2.32.0.250228'
+    default: '2.33.2.250410'
 
 steps:
   - script: |
diff --git a/tools/ci_build/github/azure-pipelines/templates/jobs/download_win_qnn_sdk.yml b/tools/ci_build/github/azure-pipelines/templates/jobs/download_win_qnn_sdk.yml
index 62399443dfd35..3b27060b3fcec 100644
--- a/tools/ci_build/github/azure-pipelines/templates/jobs/download_win_qnn_sdk.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/jobs/download_win_qnn_sdk.yml
@@ -1,7 +1,7 @@
 parameters:
   - name: QnnSDKVersion
     type: string
-    default: '2.32.0.250228'
+    default: '2.33.2.250410'
 
 steps:
   - powershell: |
diff --git a/tools/ci_build/github/azure-pipelines/templates/py-linux-qnn.yml b/tools/ci_build/github/azure-pipelines/templates/py-linux-qnn.yml
index f9d651c79d604..c361fe678699e 100644
--- a/tools/ci_build/github/azure-pipelines/templates/py-linux-qnn.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/py-linux-qnn.yml
@@ -26,7 +26,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
   
 - name: is1ES
   displayName: 'Whether the pipeline is running in 1ES'
diff --git a/tools/ci_build/github/azure-pipelines/templates/py-win-arm64-qnn.yml b/tools/ci_build/github/azure-pipelines/templates/py-win-arm64-qnn.yml
index f5c597ab50af9..c1f47de63c38c 100644
--- a/tools/ci_build/github/azure-pipelines/templates/py-win-arm64-qnn.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/py-win-arm64-qnn.yml
@@ -7,7 +7,7 @@ parameters:
 - name: QNN_SDK
   displayName: QNN SDK Version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 - name: ENV_SETUP_SCRIPT
   type: string
diff --git a/tools/ci_build/github/azure-pipelines/templates/py-win-arm64ec-qnn.yml b/tools/ci_build/github/azure-pipelines/templates/py-win-arm64ec-qnn.yml
index e8665d9d46d41..6df46bfc8e1b0 100644
--- a/tools/ci_build/github/azure-pipelines/templates/py-win-arm64ec-qnn.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/py-win-arm64ec-qnn.yml
@@ -7,7 +7,7 @@ parameters:
 - name: QNN_SDK
   displayName: QNN SDK Version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 - name: ENV_SETUP_SCRIPT
   type: string
diff --git a/tools/ci_build/github/azure-pipelines/templates/py-win-x64-qnn.yml b/tools/ci_build/github/azure-pipelines/templates/py-win-x64-qnn.yml
index 8f910e8305b76..72c8323d032ed 100644
--- a/tools/ci_build/github/azure-pipelines/templates/py-win-x64-qnn.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/py-win-x64-qnn.yml
@@ -7,7 +7,7 @@ parameters:
 - name: QNN_SDK
   displayName: QNN SDK Version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 - name: ENV_SETUP_SCRIPT
   type: string
diff --git a/tools/ci_build/github/azure-pipelines/templates/qnn-ep-win.yml b/tools/ci_build/github/azure-pipelines/templates/qnn-ep-win.yml
index a799d2eb44a20..11560486dfd6c 100644
--- a/tools/ci_build/github/azure-pipelines/templates/qnn-ep-win.yml
+++ b/tools/ci_build/github/azure-pipelines/templates/qnn-ep-win.yml
@@ -1,5 +1,5 @@
 parameters:
-  QnnSdk: '2.32.0.250228'
+  QnnSdk: '2.33.2.250410'
   build_config: 'RelWithDebInfo'
   IsReleaseBuild: false
   DoEsrp: false
diff --git a/tools/ci_build/github/azure-pipelines/win-qnn-arm64-ci-pipeline.yml b/tools/ci_build/github/azure-pipelines/win-qnn-arm64-ci-pipeline.yml
index 6ea497fab6a8a..bc4e0de149b54 100644
--- a/tools/ci_build/github/azure-pipelines/win-qnn-arm64-ci-pipeline.yml
+++ b/tools/ci_build/github/azure-pipelines/win-qnn-arm64-ci-pipeline.yml
@@ -33,7 +33,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 jobs:
 - job: 'BUILD_QNN_EP'
diff --git a/tools/ci_build/github/azure-pipelines/win-qnn-ci-pipeline.yml b/tools/ci_build/github/azure-pipelines/win-qnn-ci-pipeline.yml
index eea2af585595a..b83621d285f9a 100644
--- a/tools/ci_build/github/azure-pipelines/win-qnn-ci-pipeline.yml
+++ b/tools/ci_build/github/azure-pipelines/win-qnn-ci-pipeline.yml
@@ -33,7 +33,7 @@ parameters:
 - name: QnnSdk
   displayName: QNN SDK version
   type: string
-  default: 2.32.0.250228
+  default: 2.33.2.250410
 
 jobs:
 - job: 'BUILD_QNN_EP'