diff --git a/onnxruntime/core/mlas/lib/mlasi.h b/onnxruntime/core/mlas/lib/mlasi.h
index 7532f8eeb5a9b..4782e479753a2 100644
--- a/onnxruntime/core/mlas/lib/mlasi.h
+++ b/onnxruntime/core/mlas/lib/mlasi.h
@@ -1455,6 +1455,9 @@ MlasConvDepthwiseFloat_CHW(
 #endif
 #elif defined(MLAS_TARGET_WASM_SIMD)
 #define MLAS_WASM_SIMD_INTRINSICS
+#if defined(MLAS_TARGET_WASM_RELAXED_SIMD)
+#define MLAS_WASM_RELAXED_SIMD_INTRINSICS
+#endif
 #elif defined(MLAS_TARGET_LARCH64)
 #define MLAS_LSX_INTRINSICS
 #endif
@@ -2265,6 +2268,8 @@ MlasMaximumFloat32x4(MLAS_FLOAT32X4 Vector1, MLAS_FLOAT32X4 Vector2)
 #elif defined(MLAS_VSX_INTRINSICS)
     // Don't use vec_max to avoid undefined behavior if NAN
     return vec_sel(Vector2, Vector1, vec_cmpgt(Vector1, Vector2));
+#elif defined(MLAS_WASM_RELAXED_SIMD_INTRINSICS)
+    return wasm_f32x4_relaxed_max(Vector1, Vector2);
 #elif defined(MLAS_WASM_SIMD_INTRINSICS)
     return wasm_f32x4_max(Vector1, Vector2);
 #elif defined(MLAS_LSX_INTRINSICS)
@@ -2285,6 +2290,8 @@ MlasMinimumFloat32x4(MLAS_FLOAT32X4 Vector1, MLAS_FLOAT32X4 Vector2)
 #elif defined(MLAS_VSX_INTRINSICS)
     // Don't use vec_min to avoid undefined behavior if NAN
     return vec_sel(Vector2, Vector1, vec_cmpgt(Vector2, Vector1));
+#elif defined(MLAS_WASM_RELAXED_SIMD_INTRINSICS)
+    return wasm_f32x4_relaxed_min(Vector1, Vector2);
 #elif defined(MLAS_WASM_SIMD_INTRINSICS)
     return wasm_f32x4_min(Vector1, Vector2);
 #elif defined(MLAS_LSX_INTRINSICS)