diff --git a/autogen/oai/anthropic.py b/autogen/oai/anthropic.py
index 62078d42631d..9936b44cf4e4 100644
--- a/autogen/oai/anthropic.py
+++ b/autogen/oai/anthropic.py
@@ -78,17 +78,30 @@
 
 
 class AnthropicClient:
-    def __init__(self, **kwargs: Any):
+    def __init__(
+        self,
+        api_key: str | None = None,
+        aws_access_key: str | None = None,
+        aws_secret_key: str | None = None,
+        aws_session_token: str | None = None,
+        aws_region: str | None = None,
+        **kwargs: Any,
+    ):
         """
         Initialize the Anthropic API client.
         Args:
             api_key (str): The API key for the Anthropic API or set the `ANTHROPIC_API_KEY` environment variable.
+            aws_access_key (str, optional): AWS Access Key. If not provided, it will try to get it from the `AWS_ACCESS_KEY` environment variable.
+            aws_secret_key (str, optional): AWS Secret Key. If not provided, it will try to get it from the `AWS_SECRET_KEY` environment variable.
+            aws_session_token (str, optional): AWS Session Token. If not provided, it will try to get it from the `AWS_SESSION_TOKEN` environment variable.
+            aws_region (str, optional): AWS Region. If not provided, it will try to get it from the `AWS_REGION` environment variable.
+            **kwargs: Other parameters.
         """
-        self._api_key = kwargs.get("api_key", None)
-        self._aws_access_key = kwargs.get("aws_access_key", None)
-        self._aws_secret_key = kwargs.get("aws_secret_key", None)
-        self._aws_session_token = kwargs.get("aws_session_token", None)
-        self._aws_region = kwargs.get("aws_region", None)
+        self._api_key = api_key
+        self._aws_access_key = aws_access_key
+        self._aws_secret_key = aws_secret_key
+        self._aws_session_token = aws_session_token
+        self._aws_region = aws_region
 
         if not self._api_key:
             self._api_key = os.getenv("ANTHROPIC_API_KEY")
@@ -106,10 +119,7 @@ def __init__(self, **kwargs: Any):
             self._aws_region = os.getenv("AWS_REGION")
 
         if self._api_key is None and (
-            self._aws_access_key is None
-            or self._aws_secret_key is None
-            or self._aws_session_token is None
-            or self._aws_region is None
+            self._aws_access_key is None or self._aws_secret_key is None or self._aws_region is None
         ):
             raise ValueError("API key or AWS credentials are required to use the Anthropic API.")
 
diff --git a/autogen/oai/client.py b/autogen/oai/client.py
index 4e9d794a1f75..e8c6bfe416fd 100644
--- a/autogen/oai/client.py
+++ b/autogen/oai/client.py
@@ -370,7 +370,8 @@ class OpenAIWrapper:
 
     openai_kwargs = set(inspect.getfullargspec(OpenAI.__init__).kwonlyargs)
     aopenai_kwargs = set(inspect.getfullargspec(AzureOpenAI.__init__).kwonlyargs)
-    openai_kwargs = openai_kwargs | aopenai_kwargs
+    anthropic_kwargs = set(inspect.getfullargspec(AnthropicClient.__init__).args)
+    openai_kwargs = openai_kwargs | aopenai_kwargs | anthropic_kwargs
     total_usage_summary: Optional[Dict[str, Any]] = None
     actual_usage_summary: Optional[Dict[str, Any]] = None