diff --git a/src/Meziantou.Analyzer/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzer.cs b/src/Meziantou.Analyzer/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzer.cs
index 15ee26ee..d8722abb 100644
--- a/src/Meziantou.Analyzer/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzer.cs
+++ b/src/Meziantou.Analyzer/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzer.cs
@@ -75,7 +75,8 @@ private static void AnalyzeInvocation(OperationAnalysisContext context, IMethodS
         if (interpolatedStringArgument is IInterpolatedStringHandlerCreationOperation handlerCreation)
         {
             var interpolatedStringContent = handlerCreation.Content;
-            if (!cultureSensitiveContext.IsCultureSensitiveOperation(interpolatedStringContent, CultureSensitiveOptions.None))
+            // Use UnwrapNullableOfT to check the underlying type of nullable types
+            if (!cultureSensitiveContext.IsCultureSensitiveOperation(interpolatedStringContent, CultureSensitiveOptions.UnwrapNullableOfT))
             {
                 context.ReportDiagnostic(Rule, operation);
             }
diff --git a/tests/Meziantou.Analyzer.Test/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzerTests.cs b/tests/Meziantou.Analyzer.Test/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzerTests.cs
index 07720b52..4ec86815 100644
--- a/tests/Meziantou.Analyzer.Test/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzerTests.cs
+++ b/tests/Meziantou.Analyzer.Test/Rules/SimplifyStringCreateWhenAllParametersAreCultureInvariantAnalyzerTests.cs
@@ -291,6 +291,52 @@ await CreateProjectBuilder()
               .ValidateAsync();
     }
 
+    [Fact]
+    public async Task StringCreateWithInvariantCulture_WithNullableInteger_NoDiagnostic()
+    {
+        const string SourceCode = """
+using System;
+using System.Globalization;
+
+class TypeName
+{
+    public void Test()
+    {
+        int? n = 42;
+        var s = string.Create(CultureInfo.InvariantCulture, $"/v{n}");
+    }
+}
+""";
+        await CreateProjectBuilder()
+              .WithLanguageVersion(Microsoft.CodeAnalysis.CSharp.LanguageVersion.CSharp10)
+              .WithTargetFramework(TargetFramework.Net6_0)
+              .WithSourceCode(SourceCode)
+              .ValidateAsync();
+    }
+
+    [Fact]
+    public async Task StringCreateWithInvariantCulture_WithNullableDouble_NoDiagnostic()
+    {
+        const string SourceCode = """
+using System;
+using System.Globalization;
+
+class TypeName
+{
+    public void Test()
+    {
+        double? value = 3.14;
+        var s = string.Create(CultureInfo.InvariantCulture, $"Value: {value}");
+    }
+}
+""";
+        await CreateProjectBuilder()
+              .WithLanguageVersion(Microsoft.CodeAnalysis.CSharp.LanguageVersion.CSharp10)
+              .WithTargetFramework(TargetFramework.Net6_0)
+              .WithSourceCode(SourceCode)
+              .ValidateAsync();
+    }
+
     [Fact]
     public async Task StringCreateWithInvariantCulture_EmptyString_ShouldReport()
     {