diff --git a/.changeset/pink-pots-fold.md b/.changeset/pink-pots-fold.md
new file mode 100644
index 0000000000..5e36d35f24
--- /dev/null
+++ b/.changeset/pink-pots-fold.md
@@ -0,0 +1,15 @@
+---
+"@lynx-js/web-mainthread-apis": patch
+"@lynx-js/web-core": patch
+---
+
+refactor: isolate the globalThis in mts
+
+After this commit, developers' mts code won't be able to access the globalThis
+
+The following usage will NOT work
+
+```
+globalThis.foo = () =>{};
+foo();//crash
+```
diff --git a/packages/web-platform/web-core/src/utils/loadTemplate.ts b/packages/web-platform/web-core/src/utils/loadTemplate.ts
index f10fdce8e7..45cb657886 100644
--- a/packages/web-platform/web-core/src/utils/loadTemplate.ts
+++ b/packages/web-platform/web-core/src/utils/loadTemplate.ts
@@ -37,6 +37,57 @@ return module.exports;}`,
 const mainThreadInjectVars = [
   'lynx',
   'globalThis',
+  '__AddConfig',
+  '__AddDataset',
+  '__GetAttributes',
+  '__GetComponentID',
+  '__GetDataByKey',
+  '__GetDataset',
+  '__GetElementConfig',
+  '__GetElementUniqueID',
+  '__GetID',
+  '__GetTag',
+  '__SetAttribute',
+  '__SetConfig',
+  '__SetDataset',
+  '__SetID',
+  '__UpdateComponentID',
+  '__GetConfig',
+  '__UpdateListCallbacks',
+  '__AppendElement',
+  '__ElementIsEqual',
+  '__FirstElement',
+  '__GetChildren',
+  '__GetParent',
+  '__InsertElementBefore',
+  '__LastElement',
+  '__NextElement',
+  '__RemoveElement',
+  '__ReplaceElement',
+  '__ReplaceElements',
+  '__SwapElement',
+  '__CreateComponent',
+  '__CreateElement',
+  '__CreatePage',
+  '__CreateView',
+  '__CreateText',
+  '__CreateRawText',
+  '__CreateImage',
+  '__CreateScrollView',
+  '__CreateWrapperElement',
+  '__CreateList',
+  '__AddEvent',
+  '__GetEvent',
+  '__GetEvents',
+  '__SetEvents',
+  '__AddClass',
+  '__SetClasses',
+  '__GetClasses',
+  '__AddInlineStyle',
+  '__SetInlineStyles',
+  '__SetCSSId',
+  '__OnLifecycleEvent',
+  '__FlushElementTree',
 ];
 
 const backgroundInjectVars = [
diff --git a/packages/web-platform/web-mainthread-apis/src/MainThreadRuntime.ts b/packages/web-platform/web-mainthread-apis/src/MainThreadRuntime.ts
index 51b9c45f68..59f8fe8432 100644
--- a/packages/web-platform/web-mainthread-apis/src/MainThreadRuntime.ts
+++ b/packages/web-platform/web-mainthread-apis/src/MainThreadRuntime.ts
@@ -104,13 +104,7 @@ export class MainThreadRuntime {
   }
 
   get globalThis() {
-    const global = Object.assign(globalThis, this);
-    Object.defineProperty(
-      global,
-      'renderPage',
-      Object.getOwnPropertyDescriptor(this, 'renderPage')!,
-    );
-    return global;
+    return this;
   }
 
   lynx: MainThreadLynx;
diff --git a/packages/web-platform/web-tests/resources/web-core.main-thread.json b/packages/web-platform/web-tests/resources/web-core.main-thread.json
index ceb6b0d2a9..5eac4dd7e9 100644
--- a/packages/web-platform/web-tests/resources/web-core.main-thread.json
+++ b/packages/web-platform/web-tests/resources/web-core.main-thread.json
@@ -1,7 +1,7 @@
 {
   "styleInfo": {},
   "lepusCode": {
-    "root": "globalThis.runtime = lynx_runtime;globalThis.__lynx_worker_type = 'main'",
+    "root": "self.runtime = lynx_runtime;self.__lynx_worker_type = 'main'",
     "/manifest-chunk.js": "module.exports = 'hello';",
     "/manifest-chunk2.js": "module.exports = 'world';"
   },
diff --git a/packages/web-platform/web-tests/tests/react.spec.ts b/packages/web-platform/web-tests/tests/react.spec.ts
index 7ab02f14f1..249520d078 100644
--- a/packages/web-platform/web-tests/tests/react.spec.ts
+++ b/packages/web-platform/web-tests/tests/react.spec.ts
@@ -1229,6 +1229,7 @@ test.describe('reactlynx3 tests', () => {
         'basic-element-text-set-native-props-with-setData',
         async ({ page }, { title }) => {
           await goto(page, title);
+          await wait(200);
           // --initialtextinitial
           let count = await page.getByText('--').count();
           expect(count).toBe(1);
diff --git a/packages/web-platform/web-tests/tests/web-core.test.ts b/packages/web-platform/web-tests/tests/web-core.test.ts
index bf058a3b86..011164aed5 100644
--- a/packages/web-platform/web-tests/tests/web-core.test.ts
+++ b/packages/web-platform/web-tests/tests/web-core.test.ts
@@ -54,11 +54,11 @@ test.describe('web core tests', () => {
     await goto(page);
     const mainWorker = await getMainThreadWorker(page);
     await mainWorker.evaluate(() => {
-      globalThis.renderPage = () => {
-        const root = __CreatePage('0', '0', {});
-        const element = __CreateElement('view', '0', {});
-        __AppendElement(root, element);
-        const component = __CreateComponent(
+      globalThis.runtime.renderPage = () => {
+        const root = globalThis.runtime.__CreatePage('0', '0', {});
+        const element = globalThis.runtime.__CreateElement('view', '0', {});
+        globalThis.runtime.__AppendElement(root, element);
+        const component = globalThis.runtime.__CreateComponent(
           '1',
           '0-13826000',
           '0',
@@ -68,8 +68,8 @@ test.describe('web core tests', () => {
           {},
           {},
         );
-        __AddClass(component, 'wrapper');
-        __AppendElement(element, component);
+        globalThis.runtime.__AddClass(component, 'wrapper');
+        globalThis.runtime.__AppendElement(element, component);
       };
     });
     const backWorker = await getBackgroundThreadWorker(page);