diff --git a/lib/internal/bootstrap/node.js b/lib/internal/bootstrap/node.js
index 7299e71db52970..9f99d149d9fd71 100644
--- a/lib/internal/bootstrap/node.js
+++ b/lib/internal/bootstrap/node.js
@@ -318,6 +318,24 @@
       for (var i = 0; i < arguments.length; i++)
         this.push(arguments[i]);
     }
+
+    // Deprecated specific process.binding() modules, but not all, allow
+    // selective fallback to internalBinding for the deprecated ones.
+    const processBinding = process.binding;
+    const internalBindingWhitelist = new Set(['uv']);
+    const internalBindingWarned = new Set();
+    process.binding = function binding(name) {
+      if (internalBindingWhitelist.has(name)) {
+        if (!internalBindingWarned.has(name)) {
+          process.emitWarning(
+            `Use of process.binding('${name}') is deprecated.`,
+            'DeprecationWarning', 'DEP0111');
+          internalBindingWarned.add(name);
+        }
+        return internalBinding(name);
+      }
+      return processBinding(name);
+    };
   }
 
   function setupGlobalVariables() {
diff --git a/test/parallel/test-process-binding-deprecation.js b/test/parallel/test-process-binding-deprecation.js
new file mode 100644
index 00000000000000..25a1dfd772ea5d
--- /dev/null
+++ b/test/parallel/test-process-binding-deprecation.js
@@ -0,0 +1,13 @@
+// Flags: --no-warnings
+'use strict';
+
+const common = require('../common');
+const assert = require('assert');
+
+common.expectWarning(
+  'DeprecationWarning',
+  'Use of process.binding(\'uv\') is deprecated.',
+  'DEP0111'
+);
+
+assert(process.binding('uv'));