diff --git a/homeassistant/components/plugwise/__init__.py b/homeassistant/components/plugwise/__init__.py
index efb97f51c414aa..07d59aad8087f6 100644
--- a/homeassistant/components/plugwise/__init__.py
+++ b/homeassistant/components/plugwise/__init__.py
@@ -35,8 +35,17 @@ async def async_setup(hass: HomeAssistant, config: dict):
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     """Set up Plugwise Smiles from a config entry."""
     websession = async_get_clientsession(hass, verify_ssl=False)
+
+    if ":" in entry.data["host"]:
+        port = int(entry.data["host"].split(":")[1])
+    else:
+        port = 80
+
     api = Smile(
-        host=entry.data["host"], password=entry.data["password"], websession=websession
+        host=entry.data["host"].split(":")[0],
+        password=entry.data["password"],
+        port=port,
+        websession=websession,
     )
 
     try:
diff --git a/homeassistant/components/plugwise/config_flow.py b/homeassistant/components/plugwise/config_flow.py
index b02bb3cb92b927..a8148573c4258a 100644
--- a/homeassistant/components/plugwise/config_flow.py
+++ b/homeassistant/components/plugwise/config_flow.py
@@ -39,9 +39,16 @@ async def validate_input(hass: core.HomeAssistant, data):
     Data has the keys from _base_schema() with values provided by the user.
     """
     websession = async_get_clientsession(hass, verify_ssl=False)
+
+    if ":" in data[CONF_HOST]:
+        port = int(data[CONF_HOST].split(":")[1])
+    else:
+        port = 80
+
     api = Smile(
-        host=data[CONF_HOST],
+        host=data[CONF_HOST].split(":")[0],
         password=data[CONF_PASSWORD],
+        port=port,
         timeout=30,
         websession=websession,
     )