diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 6ef8613ad96b8..82e5622b6901e 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -68,7 +68,7 @@ standard-aifc==3.13.0
 standard-telnetlib==3.13.0
 typing-extensions>=4.13.0,<5.0
 ulid-transform==1.4.0
-urllib3>=1.26.5,<2
+urllib3>=2
 uv==0.7.1
 voluptuous-openapi==0.1.0
 voluptuous-serialize==2.6.0
diff --git a/pyproject.toml b/pyproject.toml
index 955b2a707a5c5..81070baa0b087 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -114,9 +114,7 @@ dependencies = [
   "typing-extensions>=4.13.0,<5.0",
   "ulid-transform==1.4.0",
   # Constrain urllib3 to ensure we deal with CVE-2020-26137 and CVE-2021-33503
-  # Temporary setting an upper bound, to prevent compat issues with urllib3>=2
-  # https://github.com/home-assistant/core/issues/97248
-  "urllib3>=1.26.5,<2",
+  "urllib3>=2",
   "uv==0.7.1",
   "voluptuous==0.15.2",
   "voluptuous-serialize==2.6.0",
diff --git a/requirements.txt b/requirements.txt
index 7d15999bb3882..016c535016392 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -53,7 +53,7 @@ standard-aifc==3.13.0
 standard-telnetlib==3.13.0
 typing-extensions>=4.13.0,<5.0
 ulid-transform==1.4.0
-urllib3>=1.26.5,<2
+urllib3>=2
 uv==0.7.1
 voluptuous==0.15.2
 voluptuous-serialize==2.6.0