diff --git a/Terminal.Gui/Views/Markdown/MarkdownView.Mouse.cs b/Terminal.Gui/Views/Markdown/MarkdownView.Mouse.cs
index 62e68ba58f..694a5d3253 100644
--- a/Terminal.Gui/Views/Markdown/MarkdownView.Mouse.cs
+++ b/Terminal.Gui/Views/Markdown/MarkdownView.Mouse.cs
@@ -59,7 +59,10 @@ private void SetupBindingsAndCommands ()
 
         // The base class binds LeftButtonReleased → Activate; remove that so Activate
         // fires only on LeftButtonClicked (not twice per click which would clear selection).
+        // Also remove the base class Ctrl+LeftButtonReleased → Context binding so that
+        // Ctrl+Click can follow links without triggering the context menu popover.
         MouseBindings.Remove (MouseFlags.LeftButtonReleased);
+        MouseBindings.Remove (MouseFlags.LeftButtonReleased | MouseFlags.Ctrl);
         MouseBindings.ReplaceCommands (MouseFlags.LeftButtonClicked, Command.Activate);
 
         // Right-click is handled directly in OnMouseEvent so that the view can be focused
diff --git a/Tests/UnitTestsParallelizable/Views/Markdown/MarkdownViewSelectionTests.cs b/Tests/UnitTestsParallelizable/Views/Markdown/MarkdownViewSelectionTests.cs
index 156bba53c3..5aa297745e 100644
--- a/Tests/UnitTestsParallelizable/Views/Markdown/MarkdownViewSelectionTests.cs
+++ b/Tests/UnitTestsParallelizable/Views/Markdown/MarkdownViewSelectionTests.cs
@@ -250,6 +250,49 @@ public void MouseBindings_LeftButtonPressedPositionReport_IsBoundTo_Activate ()
         mv.Dispose ();
     }
 
+    // Copilot - Regression: #5272 — Ctrl+LeftButtonReleased must NOT be bound to Context
+    // The base View class adds this binding; Markdown must remove it so Ctrl+Click can follow
+    // links without triggering the context menu popover.
+    [Fact]
+    public void MouseBindings_CtrlLeftButtonReleased_IsNotBoundTo_Context ()
+    {
+        Terminal.Gui.Views.Markdown mv = new ();
+
+        bool found = mv.MouseBindings.TryGet (MouseFlags.LeftButtonReleased | MouseFlags.Ctrl, out _);
+
+        Assert.False (found);
+
+        mv.Dispose ();
+    }
+
+    // Copilot - Regression: #5272 — Ctrl+Click on a link opens the link and does NOT show context menu
+    [Fact]
+    public void CtrlClick_On_Link_Opens_Link_And_Does_Not_Show_Context_Menu ()
+    {
+        (IApplication app, Runnable window, Terminal.Gui.Views.Markdown mv) = CreateMv ("[Click](https://example.com)");
+
+        mv.SetFocus ();
+
+        var linkClicked = false;
+
+        mv.LinkClicked += (_, e) =>
+                          {
+                              linkClicked = true;
+                              e.Handled = true;
+                          };
+
+        // Simulate Ctrl+Click: press, Ctrl+release, Ctrl+clicked
+        mv.NewMouseEvent (new Mouse { Position = new Point (0, 0), Flags = MouseFlags.LeftButtonPressed });
+        mv.NewMouseEvent (new Mouse { Position = new Point (0, 0), Flags = MouseFlags.LeftButtonReleased | MouseFlags.Ctrl });
+        mv.NewMouseEvent (new Mouse { Position = new Point (0, 0), Flags = MouseFlags.LeftButtonClicked });
+
+        Assert.True (linkClicked);
+        Assert.True (mv.ContextMenu is null || !mv.ContextMenu.Visible);
+
+        window.Dispose ();
+        app.Dispose ();
+    }
+
     // Copilot - verifies that a drag (press + position-report) activates the selection
     [Fact]
     public void Drag_Mouse_Creates_Selection ()